Compounds

Type:
Unknown

AlogP:
2.34

Polar Surface Area:
73.34

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.94

DETAILS

ALA4593019

Name:
6-methyl-N-(4-methylthiazol-2-yl)-4-(oxetan-2-ylmethoxy)picolinamide

Mol. Formula:
C15H17N3O3S

M.W.:
319.39

Type:
Unknown

AlogP:
2.57

Polar Surface Area:
73.34

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.92

DETAILS

ALA4592623

Name:
4-cyclobutoxy-N-(5-fluoropyridin-2-yl)-6-methylpicolinamide

Mol. Formula:
C16H16FN3O2

M.W.:
301.32

Type:
Unknown

AlogP:
3.11

Polar Surface Area:
64.11

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.94

DETAILS

ALA4592158

Name:
(4R,5R)-5-(4-Fluorophenyl)-4-(5-(pyridin-2-ylethynyl)pyridin-3-yl)oxazolidiShow More⌵

Mol. Formula:
C21H14FN3O2

M.W.:
359.36

9 activity values

Type:
Unknown

AlogP:
3.54

Polar Surface Area:
64.11

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA4591221

Name:
(2-tert-butyl-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)(naphthalen-2-yl)mShow More⌵

Mol. Formula:
C21H23N3O

M.W.:
333.44

Type:
Unknown

AlogP:
3.99

Polar Surface Area:
38.13

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4588437

Name:
(4R,5R)-5-(4-Chlorophenyl)-4-(5-(phenylethynyl)pyridin-3-yl)oxazolidin-2-onShow More⌵

Mol. Formula:
C22H15ClN2O2

M.W.:
374.83

4 activity values

Type:
Unknown

AlogP:
4.66

Polar Surface Area:
51.22

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4587532

Name:
6-methyl-N-(pyridin-2-yl)-4-(tetrahydro-2H-pyran-4-yloxy)picolinamide

Mol. Formula:
C17H19N3O3

M.W.:
313.36

Type:
Unknown

AlogP:
2.60

Polar Surface Area:
73.34

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.94

DETAILS

ALA4587488

Name:
phenyl{2-(pyridin-3-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl}methanonShow More⌵

Mol. Formula:
C18H16N4O

M.W.:
304.35

Type:
Unknown

AlogP:
2.60

Polar Surface Area:
51.02

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA4584928

Name:
6-methyl-N-(4-methylthiazol-2-yl)-4-(tetrahydrothiophen-3-yloxy)picolinamidShow More⌵

Mol. Formula:
C15H17N3O2S2

M.W.:
335.45

Type:
Unknown

AlogP:
3.29

Polar Surface Area:
64.11

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.93

DETAILS

ALA4580724

Name:
N-(5-fluoropyridin-2-yl)-6-methyl-4-((tetrahydrofuran-3-yl)methoxy)picolinaShow More⌵

Mol. Formula:
C17H18FN3O3

M.W.:
331.35

Type:
Unknown

AlogP:
2.59

Polar Surface Area:
73.34

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA4580610

Name:
(4R,5R)-5-Phenyl-4-(5-(phenylethynyl)pyridin-3-yl)oxazolidin-2-one

Mol. Formula:
C22H16N2O2

M.W.:
340.38

10 activity values

Type:
Unknown

AlogP:
4.00

Polar Surface Area:
51.22

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA4578429

Name:
(4R,5R)-5-(4-Fluorophenyl)-4-(5-(pyridin-4-ylethynyl)pyridin-3-yl)oxazolidiShow More⌵

Mol. Formula:
C21H14FN3O2

M.W.:
359.36

9 activity values

Type:
Unknown

AlogP:
3.54

Polar Surface Area:
64.11

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA4578292

Name:
{2-(5-fluoropyridin-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl}(3-metShow More⌵

Mol. Formula:
C19H17FN4O

M.W.:
336.37

Type:
Unknown

AlogP:
3.05

Polar Surface Area:
51.02

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA4576884

Name:
N-(5-fluoropyridin-2-yl)-6-methyl-4-(tetrahydro-2H-pyran-3-yloxy)picolinamiShow More⌵

Mol. Formula:
C17H18FN3O3

M.W.:
331.35

Type:
Unknown

AlogP:
2.73

Polar Surface Area:
73.34

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.93

DETAILS

ALA4576019

Name:
{2-(5-fluoropyridin-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl}(phenyShow More⌵

Mol. Formula:
C18H15FN4O

M.W.:
322.34

Type:
Unknown

AlogP:
2.74

Polar Surface Area:
51.02

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA4575547

Name:
(4R,5R)-5-(4-Fluorophenyl)-4-(5-((2-fluoropyridin-4-yl)ethynyl)pyridin-3-ylShow More⌵

Mol. Formula:
C21H13F2N3O2

M.W.:
377.35

9 activity values

Type:
Unknown

AlogP:
3.68

Polar Surface Area:
64.11

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA4574977

Name:
(4R,5R)-5-(2,4-Difluorophenyl)-4-(5-(phenylethynyl)pyridin-3-yl)oxazolidin-Show More⌵

Mol. Formula:
C22H14F2N2O2

M.W.:
376.36

5 activity values

Type:
Unknown

AlogP:
4.28

Polar Surface Area:
51.22

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4574683

Name:
N-(4-(fluoromethyl)thiazol-2-yl)-6-methyl-4-((3R,5R)-5-methyltetrahydrofuraShow More⌵

Mol. Formula:
C16H18FN3O3S

M.W.:
351.40

Type:
Unknown

AlogP:
3.12

Polar Surface Area:
73.34

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA4574032

Name:
N-(5-fluoropyridin-2-yl)-6-methyl-4-(oxetan-2-ylmethoxy)picolinamide

Mol. Formula:
C16H16FN3O3

M.W.:
317.32