Compounds

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ALA3927587
Name:
6-{4-[5-(4-Fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-piperidin-1-yShow More⌵
Mol. Formula:
C20H18ClF4N7
M.W.:
467.86
2 activity values
2 unique targets
Type:
Small molecule
AlogP:
4.28
Polar Surface Area:
86.38
HBA:
5
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.47
DETAILS
CLOSE
ALA3924878
Name:
4-{4-[4-(4-Fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-piperidin-1-yShow More⌵
Mol. Formula:
C21H19ClF4N6
M.W.:
466.87
2 activity values
2 unique targets
Type:
Small molecule
AlogP:
4.89
Polar Surface Area:
73.49
HBA:
4
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.45
DETAILS
CLOSE
LY2584702 Tosylate
Name:
4-{4-[4-(4-Fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-pipeShow More⌵
Mol. Formula:
C28H27F4N7O3S
M.W.:
617.63
22 activity values
8 unique targets
Type:
Small molecule
AlogP:
4.30
Polar Surface Area:
75.52
HBA:
6
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.48
DETAILS
CLOSE
ALA3909070
Name:
4-{4-[4-(4-Fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-pipeShow More⌵
Mol. Formula:
C21H20ClF4N7
M.W.:
481.89
3 activity values
3 unique targets
Type:
Small molecule
AlogP:
4.30
Polar Surface Area:
75.52
HBA:
6
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.48
DETAILS
CLOSE
ALA3889534
Name:
4-{4-[4-(3-(Trifluoromethyl)-phenyl)-1H-imidazol-2-yl]-piperidin-1-yl}-1H-pShow More⌵
Mol. Formula:
C20H19ClF3N7
M.W.:
449.87
23 activity values
3 unique targets
Type:
Small molecule
AlogP:
4.15
Polar Surface Area:
86.38
HBA:
5
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.53
DETAILS
CLOSE
ALA3727630
Name:
(Z)-N-(2-hydroxyethyl)-2,4-dimethyl-5-((2-oxo-5-(2-phenylthiazol-4-yl)indolShow More⌵
Mol. Formula:
C27H24N4O3S
M.W.:
484.58
1 activity values
1 unique targets
Type:
Small molecule
AlogP:
4.64
Polar Surface Area:
107.11
HBA:
5
HBD:
4
#RO5 Violations:
---
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.30
DETAILS
CLOSE