Compounds

Type:
Unknown

AlogP:
4.77

Polar Surface Area:
65.16

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4647083

Name:
(R)-8-(4-(bis(4-chlorophenyl)methyl)-3-methylpiperazin-1-yl)-5-methyl-6-oxoShow More⌵

Mol. Formula:
C29H24Cl2N6O

M.W.:
543.46

Type:
Unknown

AlogP:
5.28

Polar Surface Area:
88.95

HBA:
7

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.35

DETAILS

ALA4646998

Name:
(R)-8-(4-(bis(4-fluorophenyl)methyl)-2-ethylpiperazin-1-yl)-5-methyl-6-oxo-Show More⌵

Mol. Formula:
C29H27F2N5O

M.W.:
499.57

Type:
Unknown

AlogP:
4.77

Polar Surface Area:
65.16

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4646970

Name:
8-((2S,5R)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)-2,5-dimethylpipShow More⌵

Mol. Formula:
C24H23F2N5O3

M.W.:
467.48

Type:
Unknown

AlogP:
3.23

Polar Surface Area:
83.62

HBA:
8

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4645744

Name:
8-((2S,5R)-4-(bis(4-fluorophenyl)methyl)-2,5-dimethylpiperazin-1-yl)-5-methShow More⌵

Mol. Formula:
C29H27F2N5O

M.W.:
499.57

Type:
Unknown

AlogP:
4.77

Polar Surface Area:
65.16

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4637336

Name:
(S)-8-(4-(bis(4-fluorophenyl)methyl)-3-methylpiperazin-1-yl)-7-chloro-5-metShow More⌵

Mol. Formula:
C28H24ClF2N5O

M.W.:
519.98

Type:
Unknown

AlogP:
5.04

Polar Surface Area:
65.16

HBA:
6

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA4633304

Name:
8-((3R)-4-((4-chlorophenyl)(phenyl)methyl)-3-methylpiperazin-1-yl)-5-methylShow More⌵

Mol. Formula:
C29H25ClN6O

M.W.:
509.01

Type:
Unknown

AlogP:
4.63

Polar Surface Area:
88.95

HBA:
7

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4585800

Name:
3-(2-(4-benzhydrylpiperazin-1-yl)-2-oxoethyl)thieno[2,3-d]pyrimidin-4(3H)-oShow More⌵

Mol. Formula:
C25H24N4O2S

M.W.:
444.56

Type:
Unknown

AlogP:
3.39

Polar Surface Area:
58.44

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA4585494

Name:
1-((4-benzylpiperidin-1-yl)methyl)-3-cyclopentylimidazolidine-2,4,5-trione

Mol. Formula:
C21H27N3O3

M.W.:
369.47

Type:
Unknown

AlogP:
2.63

Polar Surface Area:
60.93

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4546623

Name:
1-(4-benzhydrylpiperazin-1-yl)-2-(imidazo[2,1-b]thiazol-6-yl)ethanone

Mol. Formula:
C24H24N4OS

M.W.:
416.55

Type:
Unknown

AlogP:
3.87

Polar Surface Area:
40.85

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4544664

Name:
N-(2-(4-benzhydrylpiperazin-1-yl)-2-oxoethyl)furan-2-carboxamide

Mol. Formula:
C24H25N3O3

M.W.:
403.48

Type:
Unknown

AlogP:
2.94

Polar Surface Area:
65.79

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4539536

Name:
2-((4-benzhydrylpiperazin-1-yl)methyl)-2-azaspiro[4.4]nonane-1,3-dione

Mol. Formula:
C26H31N3O2

M.W.:
417.55

Type:
Unknown

AlogP:
3.67

Polar Surface Area:
43.86

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4458059

Name:
4-(3-chlorophenyl)-1-(3-(4-oxo-2-thioxo-1,2-dihydroquinazolin-3(4H)-yl)propShow More⌵

Mol. Formula:
C21H23ClN4OS

M.W.:
414.96

Type:
Unknown

AlogP:
3.92

Polar Surface Area:
44.27

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA4452357

Name:
1-(2-methoxyphenethyl)-4-((N-methylcyclohex-1-enecarboxamido)methyl)piperidShow More⌵

Mol. Formula:
C23H34N2O2

M.W.:
370.54

Type:
Unknown

AlogP:
3.91

Polar Surface Area:
32.78

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA4434660

Name:
6-(4-(3-(2-methoxyphenoxy)propyl)piperazine-1-carbonyl)pyridazin-3(2H)-one

Mol. Formula:
C19H24N4O4

M.W.:
372.43