Compounds

ALA4648299

Name:
(2S)-2-[[(2S)-2-[[(2S,4R)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]-4-hydrShow More⌵

Mol. Formula:
C33H43N7O7S

M.W.:
681.82

1 activity values

1 unique targets

Type:
Unknown

AlogP:
0.98

Polar Surface Area:
218.25

HBA:
8

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.07

DETAILS

ALA4648143

Name:
(2S)-2-[[(3S)-2-[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidine-Show More⌵

Mol. Formula:
C34H43N7O6S

M.W.:
677.83

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.24

Polar Surface Area:
189.23

HBA:
7

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.12

DETAILS

ALA4645417

Name:
(2S)-2-[[(2S)-2-[[(2S,4S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]-4-fluoShow More⌵

Mol. Formula:
C33H42FN7O6S

M.W.:
683.81

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.96

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4644649

Name:
(2S)-2-[[(2S)-2-[[(2S,4R)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]-4-fluoShow More⌵

Mol. Formula:
C33H42FN7O6S

M.W.:
683.81

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.96

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4644027

Name:
(2S)-2-[[(2S)-2-[[(2R)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]pyrrolidinShow More⌵

Mol. Formula:
C33H43N7O6S

M.W.:
665.82

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.01

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4643473

Name:
(2S)-2-[[(2S)-1-[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidine-Show More⌵

Mol. Formula:
C30H43N7O6S

M.W.:
629.78

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.66

Polar Surface Area:
189.23

HBA:
7

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.14

DETAILS

ALA4643281

Name:
(2S)-2-[[(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidineShow More⌵

Mol. Formula:
C32H42N8O6S

M.W.:
666.81

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.40

Polar Surface Area:
210.91

HBA:
8

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
14

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4642811

Name:
(2S)-2-[[(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidineShow More⌵

Mol. Formula:
C33H43N7O6S

M.W.:
665.82

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.01

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
14

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4642151

Name:
(2S)-2-[[(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidineShow More⌵

Mol. Formula:
C35H44N8O6S

M.W.:
704.85

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.49

Polar Surface Area:
213.81

HBA:
7

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
14

Passes Ro3:
N

QED Weighted:
0.06

DETAILS

ALA4640735

Name:
(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidine-2-carbonShow More⌵

Mol. Formula:
C30H34F3N3O7S

M.W.:
637.68

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.65

Polar Surface Area:
107.02

HBA:
5

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4640707

Name:
(2S)-2-[[1-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidine-2-caShow More⌵

Mol. Formula:
C30H43N7O6S

M.W.:
629.78

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.71

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.11

DETAILS

ALA4639825

Name:
(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]pyrrolidine-2-carboxamide 2,Show More⌵

Mol. Formula:
C19H22F3N3O5S

M.W.:
461.46

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.54

Polar Surface Area:
83.71

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA4638438

Name:
(2S)-2-[[(2S)-2-[[(3S)-2-[[5-(dimethylamino)-1-naphthyl]sulfonyl]-3,4-dihydShow More⌵

Mol. Formula:
C38H45N7O6S

M.W.:
727.89

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.97

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.06

DETAILS

ALA4637863

Name:
(2S)-2-[[(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidineShow More⌵

Mol. Formula:
C30H45N7O6S

M.W.:
631.80

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.81

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.11

DETAILS

ALA4636775

Name:
(2S)-2-[[(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidineShow More⌵

Mol. Formula:
C34H45N7O6S

M.W.:
679.84

9 activity values

1 unique targets

Type:
Unknown

AlogP:
2.40

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4636527

Name:
(2S)-2-[[(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidineShow More⌵

Mol. Formula:
C32H42N8O6S

M.W.:
666.81

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.40

Polar Surface Area:
210.91

HBA:
8

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
14

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4636401

Name:
(2S)-2-[[(2S)-2-[[2-[butyl-[[5-(dimethylamino)-1-naphthyl]sulfonyl]amino]acShow More⌵

Mol. Formula:
C34H47N7O6S

M.W.:
681.86

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.65

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
19

Passes Ro3:
N

QED Weighted:
0.06

DETAILS

ALA4635848

Name:
(2S)-2-[[(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]pyrrolidinShow More⌵

Mol. Formula:
C33H43N7O6S

M.W.:
665.82

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.01

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4635323

Name:
(2S)-2-[[(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]-5,5-dimetShow More⌵

Mol. Formula:
C35H47N7O6S

M.W.:
693.87

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.79

Polar Surface Area:
198.02

HBA:
7

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4632451

Name:
(2S)-2-[[(2S)-2-[[(2S)-1-[[5-(dimethylamino)-1-naphthyl]sulfonyl]piperidineShow More⌵

Mol. Formula:
C32H42N8O6S

M.W.:
666.81

1 activity values

1 unique targets

Type:
Unknown

AlogP:
1.40

Polar Surface Area:
210.91

HBA:
8

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
14

Passes Ro3:
N

QED Weighted:
0.08

DETAILS