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  1. ALA5197945

    Name:
    2-((5-chloro-2-((3-(2-(4-hydroxypiperidin-1-yl)acetamido)-1H-indazol-6-yl)aShow More

    Mol. Formula:
    C26H28ClN9O3

    M.W.:
    550.02

    Type:
    ---

    AlogP:
    3.25

    Polar Surface Area:
    160.19

    HBA:
    9

    HBD:
    6

    #RO5 Violations:
    2

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.19

    DETAILS
  2. ALA5196326

    Name:
    N-(6-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)Show More

    Mol. Formula:
    C27H32ClN9O3S

    M.W.:
    598.13

    Type:
    ---

    AlogP:
    3.86

    Polar Surface Area:
    148.24

    HBA:
    10

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.22

    DETAILS
  3. ALA5204689

    Name:
    2-((5-chloro-2-((3-(2-(pyrrolidin-1-yl)acetamido)-1H-indazol-6-yl)amino)pyrShow More

    Mol. Formula:
    C25H26ClN9O2

    M.W.:
    520.00

    Type:
    ---

    AlogP:
    3.89

    Polar Surface Area:
    139.96

    HBA:
    8

    HBD:
    5

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS
  4. ALA5202228

    Name:
    2-((5-chloro-2-((3-(2-thiomorpholinoacetamido)-1H-indazol-6-yl)amino)pyrimiShow More

    Mol. Formula:
    C25H26ClN9O2S

    M.W.:
    552.06

    Type:
    ---

    AlogP:
    3.84

    Polar Surface Area:
    139.96

    HBA:
    9

    HBD:
    5

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.22

    DETAILS
  5. ALA5200834

    Name:
    2-((5-chloro-2-((3-(2-morpholinoacetamido)-1H-indazol-6-yl)amino)pyrimidin-Show More

    Mol. Formula:
    C25H26ClN9O3

    M.W.:
    536.00

    Type:
    ---

    AlogP:
    3.12

    Polar Surface Area:
    149.19

    HBA:
    9

    HBD:
    5

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.23

    DETAILS
  6. ALA5199214

    Name:
    N-(6-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)Show More

    Mol. Formula:
    C28H34ClN9O3S

    M.W.:
    612.16

    Type:
    ---

    AlogP:
    4.25

    Polar Surface Area:
    148.24

    HBA:
    10

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.20

    DETAILS
  7. ALA5208430

    Name:
    2-((5-chloro-2-((3-(2-(4-methylpiperidin-1-yl)acetamido)-1H-indazol-6-yl)amShow More

    Mol. Formula:
    C27H30ClN9O2

    M.W.:
    548.05

    Type:
    ---

    AlogP:
    4.52

    Polar Surface Area:
    139.96

    HBA:
    8

    HBD:
    5

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.22

    DETAILS
  8. ALA5208148

    Name:
    N-(6-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)Show More

    Mol. Formula:
    C26H29ClN8O3S

    M.W.:
    569.09

    Type:
    ---

    AlogP:
    4.71

    Polar Surface Area:
    145.00

    HBA:
    9

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.23

    DETAILS
  9. ALA5208102

    Name:
    N-(2-((5-chloro-2-((3-(2-(dimethylamino)acetamido)-1H-indazol-6-yl)amino)pyShow More

    Mol. Formula:
    C24H24ClN9O2

    M.W.:
    505.97

    Type:
    ---

    AlogP:
    4.12

    Polar Surface Area:
    139.96

    HBA:
    8

    HBD:
    5

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.21

    DETAILS
  10. ALA5207601

    Name:
    2-(4-(3-cyano-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-Show More

    Mol. Formula:
    C44H46N8O6

    M.W.:
    782.90

    Type:
    ---

    AlogP:
    4.00

    Polar Surface Area:
    187.81

    HBA:
    10

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    11

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
  11. ALA5207288

    Name:
    N-(6-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)Show More

    Mol. Formula:
    C28H33ClN8O3S

    M.W.:
    597.15

    Type:
    ---

    AlogP:
    5.35

    Polar Surface Area:
    145.00

    HBA:
    9

    HBD:
    4

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.20

    DETAILS
  12. ALA5206944

    Name:
    N-(6-((5-chloro-4-((2-(methylsulfonamido)phenyl)amino)pyrimidin-2-yl)amino)Show More

    Mol. Formula:
    C22H24ClN9O3S

    M.W.:
    530.01

    Type:
    ---

    AlogP:
    3.37

    Polar Surface Area:
    157.03

    HBA:
    9

    HBD:
    5

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.22

    DETAILS
  13. ALA5206580

    Name:
    N-(6-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)Show More

    Mol. Formula:
    C27H31ClN8O4S

    M.W.:
    599.12

    Type:
    ---

    AlogP:
    4.07

    Polar Surface Area:
    165.23

    HBA:
    10

    HBD:
    5

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.19

    DETAILS
  14. ALA5195185

    Name:
    2,2,2-trichloro-N-(2-((5-chloro-2-((3-(2-(dimethylamino)acetamido)-1H-indazShow More

    Mol. Formula:
    C23H21Cl4N9O2

    M.W.:
    597.29

    Type:
    ---

    AlogP:
    5.30

    Polar Surface Area:
    139.96

    HBA:
    8

    HBD:
    5

    #RO5 Violations:
    2

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.17

    DETAILS
  15. ALA5194035

    Name:
    2-((5-chloro-2-((3-(2-(diethylamino)acetamido)-1H-indazol-6-yl)amino)pyrimiShow More

    Mol. Formula:
    C25H28ClN9O2

    M.W.:
    522.01

    Type:
    ---

    AlogP:
    4.13

    Polar Surface Area:
    139.96

    HBA:
    8

    HBD:
    5

    #RO5 Violations:
    1

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.21

    DETAILS
  16. ALA5193765

    Name:
    N-(2-((5-chloro-2-((3-(2-(dimethylamino)acetamido)-1H-indazol-6-yl)amino)pyShow More

    Mol. Formula:
    C25H26ClN9O2

    M.W.:
    520.00

    Type:
    ---

    AlogP:
    4.34

    Polar Surface Area:
    139.96

    HBA:
    8

    HBD:
    5

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.22

    DETAILS
  17. ALA5193329

    Name:
    8-(4-(4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)piperazin-1-yShow More

    Mol. Formula:
    C43H43N7O5

    M.W.:
    737.86

    Type:
    ---

    AlogP:
    4.66

    Polar Surface Area:
    149.92

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.28

    DETAILS
  18. ALA5192545

    Name:
    N-(6-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)Show More

    Mol. Formula:
    C24H27ClN8O3S

    M.W.:
    543.05

    Type:
    ---

    AlogP:
    4.18

    Polar Surface Area:
    145.00

    HBA:
    9

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS
  19. ALA5189754

    Name:
    2-(4-(1-(3-cyano-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazShow More

    Mol. Formula:
    C47H51N9O6

    M.W.:
    837.98

    Type:
    ---

    AlogP:
    3.69

    Polar Surface Area:
    191.05

    HBA:
    11

    HBD:
    4

    #RO5 Violations:
    2

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
  20. ALA5189734

    Name:
    N-(6-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)Show More

    Mol. Formula:
    C27H31ClN8O3S

    M.W.:
    583.12

    Type:
    ---

    AlogP:
    5.10

    Polar Surface Area:
    145.00

    HBA:
    9

    HBD:
    4

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.21

    DETAILS
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