Compounds

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ALA4582850
Name:
N-(4-(1-(7-(hydroxyamino)-7-oxoheptyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimShow More⌵
Mol. Formula:
C28H39N9O4
M.W.:
565.68
9 activity values
8 unique targets
Type:
Unknown
AlogP:
2.57
Polar Surface Area:
140.98
HBA:
10
HBD:
3
#RO5 Violations:
1
#Rotatable Bonds:
10
Passes Ro3:
N
QED Weighted:
0.19
DETAILS
CLOSE
ALA4535681
Name:
N-(4-(1-(7-(hydroxyamino)-7-oxoheptyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimShow More⌵
Mol. Formula:
C27H36N8O5
M.W.:
552.64
6 activity values
6 unique targets
Type:
Unknown
AlogP:
2.65
Polar Surface Area:
146.97
HBA:
10
HBD:
3
#RO5 Violations:
1
#Rotatable Bonds:
10
Passes Ro3:
N
QED Weighted:
0.20
DETAILS
CLOSE
HDACs/mTOR Inhibitor 1
Name:
(R)-N-(4-(1-(7-(hydroxyamino)-7-oxoheptyl)-4-morpholino-1H-pyrazolo[3,4-d]pShow More⌵
Mol. Formula:
C28H38N8O5
M.W.:
566.66
109 activity values
22 unique targets
Type:
Unknown
AlogP:
3.04
Polar Surface Area:
146.97
HBA:
10
HBD:
3
#RO5 Violations:
1
#Rotatable Bonds:
10
Passes Ro3:
N
QED Weighted:
0.19
DETAILS
CLOSE
ALA4473569
Name:
N-(4-(1-(7-(hydroxyamino)-7-oxoheptyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimShow More⌵
Mol. Formula:
C27H37N9O4
M.W.:
551.65
6 activity values
6 unique targets
Type:
Unknown
AlogP:
2.22
Polar Surface Area:
149.77
HBA:
10
HBD:
4
#RO5 Violations:
1
#Rotatable Bonds:
10
Passes Ro3:
N
QED Weighted:
0.17
DETAILS
CLOSE
ALA4469377
Name:
N-Hydroxy-7-(6-(4-(3-ethylureido)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrShow More⌵
Mol. Formula:
C25H34N8O4
M.W.:
510.60
6 activity values
6 unique targets
Type:
Unknown
AlogP:
2.93
Polar Surface Area:
146.53
HBA:
9
HBD:
4
#RO5 Violations:
1
#Rotatable Bonds:
11
Passes Ro3:
N
QED Weighted:
0.17
DETAILS
CLOSE
ALA4466560
Name:
N-(4-(1-(7-(hydroxyamino)-7-oxoheptyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimShow More⌵
Mol. Formula:
C27H36N8O4S
M.W.:
568.70
6 activity values
6 unique targets
Type:
Unknown
AlogP:
3.37
Polar Surface Area:
137.74
HBA:
10
HBD:
3
#RO5 Violations:
1
#Rotatable Bonds:
10
Passes Ro3:
N
QED Weighted:
0.19
DETAILS
CLOSE
ALA4437811
Name:
N-(4-(1-(7-(Hydroxyamino)-7-oxoheptyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimShow More⌵
Mol. Formula:
C29H41N9O4
M.W.:
579.71
9 activity values
8 unique targets
Type:
Unknown
AlogP:
2.96
Polar Surface Area:
140.98
HBA:
10
HBD:
3
#RO5 Violations:
1
#Rotatable Bonds:
11
Passes Ro3:
N
QED Weighted:
0.18
DETAILS
CLOSE
ALA4437152
Name:
N-Hydroxy-7-(6-(4-(3-butylureido)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrShow More⌵
Mol. Formula:
C27H38N8O4
M.W.:
538.65
6 activity values
6 unique targets
Type:
Unknown
AlogP:
3.71
Polar Surface Area:
146.53
HBA:
9
HBD:
4
#RO5 Violations:
1
#Rotatable Bonds:
13
Passes Ro3:
N
QED Weighted:
0.15
DETAILS
CLOSE