Compounds

ALA5267509

Name:
2-Amino-8-ethyl-6-(3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)-4-(2-methyl-1HShow More⌵

Mol. Formula:
C31H27N5O2

M.W.:
501.59

Type:
---

AlogP:
5.65

Polar Surface Area:
109.72

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA5266678

Name:
2-Amino-8-isopropyl-4-(5-methoxy-2-methyl-1H-indol-3-yl)-6-(3-methyl-4-oxo-Show More⌵

Mol. Formula:
C32H29N5O3

M.W.:
531.62

Type:
---

AlogP:
5.74

Polar Surface Area:
118.95

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA5281368

Name:
2-Amino-8-(tert-butyl)-4-(5-chloro-2-methyl-1H-indol-3-yl)-6-(3-methyl-4-oxShow More⌵

Mol. Formula:
C32H28ClN5O2

M.W.:
550.06

Type:
---

AlogP:
6.56

Polar Surface Area:
109.72

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA5280861

Name:
2-Amino-8-(tert-butyl)-4-(5-methoxy-2-methyl-1H-indol-3-yl)-6-(3-methyl-4-oShow More⌵

Mol. Formula:
C33H31N5O3

M.W.:
545.64

Type:
---

AlogP:
5.91

Polar Surface Area:
118.95

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA5280166

Name:
2-Amino-4-(5-methoxy-2-methyl-1H-indol-3-yl)-8-methyl-6-(3-methyl-4-oxo-3,4Show More⌵

Mol. Formula:
C30H25N5O3

M.W.:
503.56

Type:
---

AlogP:
4.93

Polar Surface Area:
118.95

HBA:
7

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5279547

Name:
2-amino-6-(3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)-8-methyl-4H-chromene-3Show More⌵

Mol. Formula:
C21H18N4O2

M.W.:
358.40

Type:
---

AlogP:
3.02

Polar Surface Area:
93.93

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5279507

Name:
2-amino-4H-chromene-3-carbonitrile

Mol. Formula:
C10H8N2O

M.W.:
172.19

Type:
---

AlogP:
1.27

Polar Surface Area:
59.04

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
---

Passes Ro3:
Y

QED Weighted:
0.64

DETAILS

ALA5279224

Name:
2-Amino-8-ethyl-4-(2-methyl-1H-indol-3-yl)-6-(3-methyl-4-oxo-3,4-dihydroquiShow More⌵

Mol. Formula:
C30H25N5O2

M.W.:
487.56

Type:
---

AlogP:
5.17

Polar Surface Area:
109.72

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5278983

Name:
2-Amino-8-ethyl-4-(2-methyl-1H-indol-3-yl)-6-(4-oxo-3,4-dihydroquinazolin-2Show More⌵

Mol. Formula:
C29H23N5O2

M.W.:
473.54

Type:
---

AlogP:
5.16

Polar Surface Area:
120.58

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA5278352

Name:
2-Amino-4-(5-methoxy-2-methyl-1H-indol-3-yl-6-(3-methyl-4-oxo-3,4-dihydroquShow More⌵

Mol. Formula:
C32H29N5O3

M.W.:
531.62

Type:
---

AlogP:
5.57

Polar Surface Area:
118.95

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA5277123

Name:
2-Amino-4-(1,2-dimethyl-1H-indol-3-yl)-6-(3-ethyl-4-oxo-3,4-dihydroquinazolShow More⌵

Mol. Formula:
C31H27N5O2

M.W.:
501.59

Type:
---

AlogP:
5.41

Polar Surface Area:
98.86

HBA:
7

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5276451

Name:
2-Amino-4-(2-methyl-1H-indol-3-yl)-4H-chromene-3-carbonitrile

Mol. Formula:
C19H15N3O

M.W.:
301.35

Type:
---

AlogP:
3.69

Polar Surface Area:
74.83

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA5275193

Name:
2-Amino-4-(5-chloro-2-methyl-1H-indol-3-yl)-8-ethyl-6-(3-methyl-4-oxo-3,4-dShow More⌵

Mol. Formula:
C30H24ClN5O2

M.W.:
522.01

Type:
---

AlogP:
5.82

Polar Surface Area:
109.72

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA5273193

Name:
2-Amino-8-(tert-butyl)-6-(3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)-4-(5-meShow More⌵

Mol. Formula:
C34H33N5O3

M.W.:
559.67

Type:
---

AlogP:
6.40

Polar Surface Area:
118.95

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA5291244

Name:
2-Amino-4-(5-chloro-2-methyl-1H-indol-3-yl)-8-methyl-6-(3-methyl-4-oxo-3,4-Show More⌵

Mol. Formula:
C29H22ClN5O2

M.W.:
507.98

Type:
---

AlogP:
5.57

Polar Surface Area:
109.72

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.32

DETAILS

ALA5288900

Name:
2-Amino-4-(5-chloro-2-methyl-1H-indol-3-yl)-8-isopropyl-6-(3-methyl-4-oxo-3Show More⌵

Mol. Formula:
C31H26ClN5O2

M.W.:
536.04

Type:
---

AlogP:
6.39

Polar Surface Area:
109.72

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA5287420

Name:
2-Amino-8-ethyl-4-(5-methoxy-2-methyl-1H-indol-3-yl)-6-(3-methyl-4-oxo-3,4-Show More⌵

Mol. Formula:
C31H27N5O3

M.W.:
517.59

Type:
---

AlogP:
5.18

Polar Surface Area:
118.95

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA5286911

Name:
2-Amino-6-(3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)-8-isopropyl-4-(2-methyShow More⌵

Mol. Formula:
C32H29N5O2

M.W.:
515.62

Type:
---

AlogP:
6.21

Polar Surface Area:
109.72

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA5286541

Name:
3-ethyl-2-methyl-3,4-dihydroquinazolin-4-one

Mol. Formula:
C11H12N2O

M.W.:
188.23

Type:
---

AlogP:
1.72

Polar Surface Area:
34.89

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
Y

QED Weighted:
0.68

DETAILS

ALA5285667

Name:
2-Amino-8-(tert-butyl)-4-(2-methyl-1H-indol-3-yl)-6-(4-oxo-3,4-dihydroquinaShow More⌵

Mol. Formula:
C31H27N5O2

M.W.:
501.59

Type:
---

AlogP:
5.90

Polar Surface Area:
120.58

HBA:
5

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.28

DETAILS