Compounds

ALA5270137

Name:
3-(2-(diethylamino)ethyl)-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-Show More⌵

Mol. Formula:
C29H32N4O5

M.W.:
516.60

Type:
---

AlogP:
2.83

Polar Surface Area:
106.32

HBA:
7

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5269625

Name:
1-(3,7-dimethyl-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hydroxy-3-iShow More⌵

Mol. Formula:
C28H29N3O5

M.W.:
487.56

Type:
---

AlogP:
3.52

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5267821

Name:
1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hydroxy-3-(2-methoxyethyShow More⌵

Mol. Formula:
C26H25N3O6

M.W.:
475.50

Type:
---

AlogP:
2.14

Polar Surface Area:
112.31

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5281131

Name:
3-cyclopropyl-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hydroxy-4,Show More⌵

Mol. Formula:
C26H23N3O5

M.W.:
457.49

Type:
---

AlogP:
2.65

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5281104

Name:
methyl 3-(cyclopropylmethyl)-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yShow More⌵

Mol. Formula:
C28H27N3O5

M.W.:
485.54

Type:
---

AlogP:
2.99

Polar Surface Area:
92.08

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5279839

Name:
1-(6,11-dihydrodibenzo[b,e]thiepin-11-yl)-5-hydroxy-3-isopropyl-4,6-dioxo-2Show More⌵

Mol. Formula:
C25H23N3O5S

M.W.:
477.54

Type:
---

AlogP:
3.41

Polar Surface Area:
103.08

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5279053

Name:
1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hydroxy-3-isopropyl-4,6-Show More⌵

Mol. Formula:
C26H25N3O5

M.W.:
459.50

Type:
---

AlogP:
2.90

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA5277835

Name:
1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-3-ethyl-5-hydroxy-4,6-dioxShow More⌵

Mol. Formula:
C25H23N3O5

M.W.:
445.48

Type:
---

AlogP:
2.51

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA5277307

Name:
1-(1,9-dimethyl-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hydroxy-3-iShow More⌵

Mol. Formula:
C28H29N3O5

M.W.:
487.56

Type:
---

AlogP:
3.52

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5276154

Name:
3-(cyclopentylmethyl)-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hyShow More⌵

Mol. Formula:
C29H29N3O5

M.W.:
499.57

Type:
---

AlogP:
3.68

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5276094

Name:
3-(cyclopropylmethyl)-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,5-Show More⌵

Mol. Formula:
C27H26N4O5

M.W.:
486.53

Type:
---

AlogP:
2.32

Polar Surface Area:
115.11

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA5273869

Name:
3-(cyclopropylmethyl)-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hyShow More⌵

Mol. Formula:
C28H26N8O4

M.W.:
538.57

Type:
---

AlogP:
1.97

Polar Surface Area:
149.34

HBA:
9

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.35

DETAILS

ALA5273778

Name:
1-([1,1'-biphenyl]-2-ylmethyl)-5-hydroxy-3-isopropyl-4,6-dioxo-2,3,4,6-tetrShow More⌵

Mol. Formula:
C24H23N3O5

M.W.:
433.46

Type:
---

AlogP:
2.88

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA5285985

Name:
1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hydroxy-3-methyl-4,6-dioShow More⌵

Mol. Formula:
C24H21N3O5

M.W.:
431.45

Type:
---

AlogP:
2.12

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA5285252

Name:
3-(cyclopropylmethyl)-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hyShow More⌵

Mol. Formula:
C27H25N3O5

M.W.:
471.51

Type:
---

AlogP:
2.90

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5290474

Name:
1-benzyl-5-hydroxy-3-isopropyl-4,6-dioxo-2,3,4,6-tetrahydro-1H-pyrido[2,1-fShow More⌵

Mol. Formula:
C18H19N3O5

M.W.:
357.37

Type:
---

AlogP:
1.21

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.85

DETAILS

ALA5290004

Name:
3-(cyclopropylmethyl)-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hyShow More⌵

Mol. Formula:
C27H25N7O3

M.W.:
495.54

Type:
---

AlogP:
2.38

Polar Surface Area:
120.24

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5289371

Name:
3-(cyclopropylmethyl)-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hyShow More⌵

Mol. Formula:
C28H25N5O5

M.W.:
511.54

Type:
---

AlogP:
2.55

Polar Surface Area:
124.67

HBA:
8

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5289170

Name:
1-(2,8-dimethyl-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hydroxy-3-iShow More⌵

Mol. Formula:
C28H29N3O5

M.W.:
487.56

Type:
---

AlogP:
3.52

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5287594

Name:
3-(cyclohexylmethyl)-1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-5-hydShow More⌵

Mol. Formula:
C30H31N3O5

M.W.:
513.59

Type:
---

AlogP:
4.07

Polar Surface Area:
103.08

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.55

DETAILS