Compounds

ALA4873385

Name:
2-(3-fluorophenyl)-N-((1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl)imidazo[1,Show More⌵

Mol. Formula:
C23H26FN3O2

M.W.:
395.48

7 activity values

4 unique targets

Type:
Unknown

AlogP:
4.20

Polar Surface Area:
66.63

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4872589

Name:
2-(3-fluorophenyl)-N-((3R,6S)-6-(2-hydroxypropan-2-yl)tetrahydro-2H-pyran-3Show More⌵

Mol. Formula:
C22H24FN3O3

M.W.:
397.45

3 activity values

3 unique targets

Type:
Unknown

AlogP:
3.19

Polar Surface Area:
75.86

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA4870703

Name:
2-(2-fluorophenyl)-N-((1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl)imidazo[1,Show More⌵

Mol. Formula:
C23H26FN3O2

M.W.:
395.48

3 activity values

3 unique targets

Type:
Unknown

AlogP:
4.20

Polar Surface Area:
66.63

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4868975

Name:
N-(1-ethylpiperidin-4-yl)-2-phenylimidazo[1,2-a]pyridine-6-carboxamide

Mol. Formula:
C21H24N4O

M.W.:
348.45

3 activity values

3 unique targets

Type:
Unknown

AlogP:
3.22

Polar Surface Area:
49.64

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA4868541

Name:
2-phenyl-N-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)imidazo[1,2-a]pyridine-6Show More⌵

Mol. Formula:
C21H21F3N4O

M.W.:
402.42

4 activity values

4 unique targets

Type:
Unknown

AlogP:
3.76

Polar Surface Area:
49.64

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA4868339

Name:
1-(3-fluorophenyl)-N-((1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl)-1H-indoleShow More⌵

Mol. Formula:
C24H27FN2O2

M.W.:
394.49

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.83

Polar Surface Area:
54.26

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA4866146

Name:
1-(3-fluorophenyl)-N-((1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl)-1H-indazoShow More⌵

Mol. Formula:
C23H26FN3O2

M.W.:
395.48

4 activity values

4 unique targets

Type:
Unknown

AlogP:
4.22

Polar Surface Area:
67.15

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4864805

Name:
N-((1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl)-2-phenylimidazo[1,2-a]pyridiShow More⌵

Mol. Formula:
C23H27N3O2

M.W.:
377.49

8 activity values

4 unique targets

Type:
Unknown

AlogP:
4.06

Polar Surface Area:
66.63

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA4859922

Name:
2-(2-fluorophenyl)-N-((3R,6S)-6-(2-hydroxypropan-2-yl)tetrahydro-2H-pyran-3Show More⌵

Mol. Formula:
C22H24FN3O3

M.W.:
397.45

7 activity values

4 unique targets

Type:
Unknown

AlogP:
3.19

Polar Surface Area:
75.86

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA4852189

Name:
1-(3-fluorophenyl)-N-((1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl)-6,7-dihydShow More⌵

Mol. Formula:
C22H29FN4O2

M.W.:
400.50

8 activity values

4 unique targets

Type:
Unknown

AlogP:
3.41

Polar Surface Area:
70.39

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.83

DETAILS

ALA4849005

Name:
2-(4-fluorophenyl)-N-((1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl)imidazo[1,Show More⌵

Mol. Formula:
C23H26FN3O2

M.W.:
395.48

2 activity values

2 unique targets

Type:
Unknown

AlogP:
4.20

Polar Surface Area:
66.63

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4847268

Name:
N-((3R,6S)-6-(2-hydroxypropan-2-yl)tetrahydro-2H-pyran-3-yl)-2-phenylimidazShow More⌵

Mol. Formula:
C22H25N3O3

M.W.:
379.46

7 activity values

4 unique targets

Type:
Unknown

AlogP:
3.05

Polar Surface Area:
75.86

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.73

DETAILS