Compounds

Type:
Unknown

AlogP:
4.24

Polar Surface Area:
210.52

HBA:
17

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.09

DETAILS

ALA4580648

Name:
4-(2-(2-(2-(4-((4-(6-(6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyriShow More⌵

Mol. Formula:
C48H57N13O8

M.W.:
944.07

9 activity values

8 unique targets

Type:
Unknown

AlogP:
3.75

Polar Surface Area:
232.21

HBA:
19

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
19

Passes Ro3:
N

QED Weighted:
0.07

DETAILS

ALA4574965

Name:
7-cyclopentyl-2-[[5-[4-[[1-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxShow More⌵

Mol. Formula:
C47H58N14O8

M.W.:
947.07

Type:
Unknown

AlogP:
2.86

Polar Surface Area:
236.40

HBA:
19

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
21

Passes Ro3:
N

QED Weighted:
0.07

DETAILS

ALA4561339

Name:
4-(5-(4-((4-(6-(6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3Show More⌵

Mol. Formula:
C45H51N13O6

M.W.:
869.99

Type:
Unknown

AlogP:
4.15

Polar Surface Area:
222.54

HBA:
17

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4557637

Name:
2-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrShow More⌵

Mol. Formula:
C49H61N11O11

M.W.:
980.09

5 activity values

Type:
Unknown

AlogP:
2.37

Polar Surface Area:
257.85

HBA:
19

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
24

Passes Ro3:
N

QED Weighted:
0.04

DETAILS

ALA4555276

Name:
4-(7-(4-((4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,Show More⌵

Mol. Formula:
C47H50N12O6

M.W.:
878.99

Type:
Unknown

AlogP:
4.48

Polar Surface Area:
210.51

HBA:
16

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.07

DETAILS

ALA4553587

Name:
4-((14-(4-((4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[Show More⌵

Mol. Formula:
C50H61N13O10

M.W.:
1004.12

3 activity values

Type:
Unknown

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

CP-10

Name:
4-((2-(2-(4-((4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyridShow More⌵

Mol. Formula:
C44H49N13O7

M.W.:
871.96

78 activity values

19 unique targets

Type:
Unknown

AlogP:
3.00

Polar Surface Area:
231.77

HBA:
18

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4548417

Name:
2-(4-(6-(6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyriShow More⌵

Mol. Formula:
C47H57N11O10

M.W.:
936.04

22 activity values

10 unique targets

Type:
Unknown

AlogP:
2.36

Polar Surface Area:
248.62

HBA:
18

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
21

Passes Ro3:
N

QED Weighted:
0.05

DETAILS

ALA4539231

Name:
4-((2-(2-(2-(2-(4-((4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydrShow More⌵

Mol. Formula:
C48H57N13O9

M.W.:
960.07

3 activity values

Type:
Unknown

AlogP:
3.03

Polar Surface Area:
250.23

HBA:
20

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
21

Passes Ro3:
N

QED Weighted:
0.05

DETAILS

ALA4520866

Name:
2-(2,6-dioxopiperidin-3-yl)-4-(2-(2-(2-(2-(4-((4-((6-(5-fluoro-4-(4-fluoro-Show More⌵

Mol. Formula:
C49H56F2N14O7

M.W.:
991.07

Type:
Unknown

AlogP:
4.27

Polar Surface Area:
228.98

HBA:
19

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
22

Passes Ro3:
N

QED Weighted:
0.06

DETAILS

ALA4469472

Name:
7-cyclopentyl-2-[[5-[4-[[1-[2-[2-[2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-iShow More⌵

Mol. Formula:
C45H54N14O7

M.W.:
903.02

Type:
Unknown

AlogP:
2.85

Polar Surface Area:
227.17

HBA:
18

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
18

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4465255

Name:
2-(4-(6-(6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyriShow More⌵

Mol. Formula:
C45H53N11O9

M.W.:
891.99

5 activity values

Type:
Unknown

AlogP:
2.34

Polar Surface Area:
239.39

HBA:
17

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
18

Passes Ro3:
N

QED Weighted:
0.06

DETAILS

ALA4456787

Name:
2-(2,6-dioxopiperidin-3-yl)-4-(2-(2-(2-(4-((4-((6-(5-fluoro-4-(4-fluoro-1-iShow More⌵

Mol. Formula:
C47H52F2N14O6

M.W.:
947.02

Type:
Unknown

AlogP:
4.26

Polar Surface Area:
219.75

HBA:
18

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
19

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4448981

Name:
7-cyclopentyl-2-[[5-[4-[[1-[2-[2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoiShow More⌵

Mol. Formula:
C43H50N14O6

M.W.:
858.96

Type:
Unknown

AlogP:
2.83

Polar Surface Area:
217.94

HBA:
17

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.10

DETAILS

ALA4448920

Name:
2-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrShow More⌵

Mol. Formula:
C47H57N11O7

M.W.:
888.04

Type:
Unknown

AlogP:
4.65

Polar Surface Area:
220.93

HBA:
15

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
18

Passes Ro3:
N

QED Weighted:
0.06

DETAILS

ALA4446318

Name:
2-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrShow More⌵

Mol. Formula:
C43H49N11O8

M.W.:
847.93

5 activity values

Type:
Unknown

AlogP:
2.32

Polar Surface Area:
230.16

HBA:
16

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4441327

Name:
4-(6-(4-((4-(6-(6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3Show More⌵

Mol. Formula:
C46H52N12O6

M.W.:
869.00

Type:
Unknown

AlogP:
4.67

Polar Surface Area:
210.51

HBA:
16

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4440866

Name:
4-(2-(2-(4-((4-(6-(6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[Show More⌵

Mol. Formula:
C46H53N13O7

M.W.:
900.01

8 activity values

8 unique targets

Type:
Unknown

AlogP:
3.73

Polar Surface Area:
222.98

HBA:
18

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4440838

Name:
4-(2-(2-(2-(4-(6-(6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2Show More⌵

Mol. Formula:
C43H50N10O8

M.W.:
834.93