Compounds

ALA5265753

Name:
N-{6-[4-(2,2-difluoroethyl)piperazin-1-yl]-2-[1-({1-[2-(2,6-dioxopiperidin-Show More⌵

Mol. Formula:
C44H49F3N12O4

M.W.:
866.95

Type:
---

AlogP:
4.17

Polar Surface Area:
156.55

HBA:
13

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5282453

Name:
N-{6-[4-(azetidin-1-yl)piperidin-1-yl]-2-[1-({1-[2-(2,6-dioxopiperidin-3-ylShow More⌵

Mol. Formula:
C47H55N11O5

M.W.:
854.03

Type:
---

AlogP:
3.75

Polar Surface Area:
159.04

HBA:
12

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5281247

Name:
N-{6-[4-(2,2-difluoroethyl)piperazin-1-yl]-2-[1-({1-[2-(2,6-dioxopiperidin-Show More⌵

Mol. Formula:
C45H49F2N11O6

M.W.:
877.95

Type:
---

AlogP:
3.11

Polar Surface Area:
176.11

HBA:
13

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA5279427

Name:
N-(6-(2,2-difluoroethoxy)-2-(1-((1-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindShow More⌵

Mol. Formula:
C40H42F2N10O5

M.W.:
780.84

Type:
---

AlogP:
4.29

Polar Surface Area:
159.30

HBA:
12

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA5291371

Name:
N-(6-(4-(azetidin-1-yl)piperidin-1-yl)-2-(1-((1-(2-(2,6-dioxopiperidin-3-ylShow More⌵

Mol. Formula:
C45H50FN11O5

M.W.:
843.96

Type:
---

AlogP:
3.07

Polar Surface Area:
159.04

HBA:
12

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5290896

Name:
N-[6-(cyclopropylmethoxy)-2-[1-({1-[2-(2,6-dioxopiperidin-3-yl)-3-oxo-2,3-dShow More⌵

Mol. Formula:
C42H46N10O5

M.W.:
770.89

Type:
---

AlogP:
4.43

Polar Surface Area:
159.30

HBA:
12

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5287889

Name:
N-{6-[4-(azetidin-1-yl)piperidin-1-yl]-2-[1-({1-[2-(2,6-dioxopiperidin-3-ylShow More⌵

Mol. Formula:
C47H55N11O5

M.W.:
854.03

Type:
---

AlogP:
3.75

Polar Surface Area:
159.04

HBA:
12

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5286107

Name:
N-{2-[1-({1-[2-(2,6-dioxopiperidin-3-yl)-4-fluoro-1-oxo-2,3-dihydro-1H-isoiShow More⌵

Mol. Formula:
C40H41F2N9O6

M.W.:
781.82

Type:
---

AlogP:
3.32

Polar Surface Area:
161.79

HBA:
11

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5285240

Name:
N-(2-(1-(2-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)azetidiShow More⌵

Mol. Formula:
C42H45N9O7

M.W.:
787.88

Type:
---

AlogP:
3.51

Polar Surface Area:
178.86

HBA:
12

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5272423

Name:
N-{2-[1-({1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-Show More⌵

Mol. Formula:
C42H45N9O7

M.W.:
787.88

Type:
---

AlogP:
3.51

Polar Surface Area:
178.86

HBA:
12

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA4799493

Name:
N-(2-(4-((3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)prShow More⌵

Mol. Formula:
C39H41F3N8O7

M.W.:
790.80

2 activity values

1 unique targets

Type:
Unknown

AlogP:
4.62

Polar Surface Area:
193.72

HBA:
11

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
14

Passes Ro3:
N

QED Weighted:
0.10

DETAILS

ALA4779516

Name:
N-(2-(4-((5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)peShow More⌵

Mol. Formula:
C41H45F3N8O7

M.W.:
818.85

2 activity values

1 unique targets

Type:
Unknown

AlogP:
5.40

Polar Surface Area:
193.72

HBA:
11

HBD:
4

#RO5 Violations:
3

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.08

DETAILS

ALA4779291

Name:
N-(2-(4-((2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)etShow More⌵

Mol. Formula:
C38H39F3N8O7

M.W.:
776.77

2 activity values

1 unique targets

Type:
Unknown

AlogP:
4.23

Polar Surface Area:
193.72

HBA:
11

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.11

DETAILS

ALA4760963

Name:
N-(2-(4-((6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)heShow More⌵

Mol. Formula:
C42H47F3N8O7

M.W.:
832.88

2 activity values

1 unique targets

Type:
Unknown

AlogP:
5.79

Polar Surface Area:
193.72

HBA:
11

HBD:
4

#RO5 Violations:
3

#Rotatable Bonds:
17

Passes Ro3:
N

QED Weighted:
0.07

DETAILS

ALA4755242

Name:
N-(2-(4-((2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)aminoShow More⌵

Mol. Formula:
C40H43F3N8O8

M.W.:
820.83

2 activity values

1 unique targets

Type:
Unknown

AlogP:
4.24

Polar Surface Area:
202.95

HBA:
12

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.09

DETAILS

ALA4751158

Name:
N-(2-(4-((7-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)heShow More⌵

Mol. Formula:
C43H49F3N8O7

M.W.:
846.91

2 activity values

1 unique targets

Type:
Unknown

AlogP:
6.18

Polar Surface Area:
193.72

HBA:
11

HBD:
4

#RO5 Violations:
3

#Rotatable Bonds:
18

Passes Ro3:
N

QED Weighted:
0.07

DETAILS

ALA4745625

Name:
N-(2-(4-((4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)buShow More⌵

Mol. Formula:
C40H43F3N8O7

M.W.:
804.83

2 activity values

1 unique targets

Type:
Unknown

AlogP:
5.01

Polar Surface Area:
193.72

HBA:
11

HBD:
4

#RO5 Violations:
3

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.09

DETAILS

ALA4462890

Name:
4-(3-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)etShow More⌵

Mol. Formula:
C38H39N5O12

M.W.:
757.75

5 activity values

5 unique targets

Type:
Unknown

AlogP:
0.88

Polar Surface Area:
224.01

HBA:
13

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
17

Passes Ro3:
N

QED Weighted:
0.10

DETAILS

ALA4445579

Name:
4-(12-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)dodec-1-ynShow More⌵

Mol. Formula:
C41H45N5O9

M.W.:
751.84

5 activity values

5 unique targets

Type:
Unknown

AlogP:
4.34

Polar Surface Area:
196.32

HBA:
10

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
17

Passes Ro3:
N

QED Weighted:
0.10

DETAILS