Compounds

Type:
---

AlogP:
6.76

Polar Surface Area:
123.27

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA5202270

Name:
(3R,5S)-1-[(2S)-2-{[(tert-butoxy)carbonyl]amino)-3,3-dimethylbutanoyl]-5-{[Show More⌵

Mol. Formula:
C35H51N4O9P

M.W.:
702.79

6 activity values

Type:
---

AlogP:
5.24

Polar Surface Area:
175.59

HBA:
10

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5197878

Name:
tert-Butyl N-[(2S)-1-[(2S,4S)-4-(4,5-dihydroxy-1H-1,2,3-triazol-1-yl)-2-{[1Show More⌵

Mol. Formula:
C34H47N6O9P

M.W.:
714.76

5 activity values

Type:
---

AlogP:
5.22

Polar Surface Area:
194.44

HBA:
12

HBD:
4

#RO5 Violations:
3

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5195588

Name:
tert-Butyl N-[(2S)-1-[(2S,4S)-2-{[1-(diphenoxyphosphoryl)-2-methylpropyl]caShow More⌵

Mol. Formula:
C32H46N3O8P

M.W.:
631.71

4 activity values

2 unique targets

Type:
---

AlogP:
5.34

Polar Surface Area:
143.50

HBA:
8

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA5195583

Name:
tert-Butyl N-[(2S)-1-[(2S,4R)-2-{[1-(diphenoxyphosphoryl)-2-methylpropyl]caShow More⌵

Mol. Formula:
C34H48N3O9P

M.W.:
673.74

8 activity values

Type:
---

AlogP:
5.91

Polar Surface Area:
149.57

HBA:
9

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA5193418

Name:
tert-Butyl N-[(2S)-1-[(2S,4R)-2-{[1-(diphenoxyphosphoryl)-2-methylpropyl]caShow More⌵

Mol. Formula:
C32H46N3O8P

M.W.:
631.71

6 activity values

Type:
---

AlogP:
5.34

Polar Surface Area:
143.50

HBA:
8

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA5190705

Name:
tert-Butyl N-[(2S)-2-[(2S,4R)-2-{[1-(diphenoyphosphotyl)2-methylpropyl]carbShow More⌵

Mol. Formula:
C37H53N6O8P

M.W.:
740.84

5 activity values

Type:
---

AlogP:
6.04

Polar Surface Area:
174.21

HBA:
11

HBD:
3

#RO5 Violations:
3

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5188060

Name:
tert-Butyl N-[(2S)-1-[(2S,4S)-2-{[1-(diphenoxyphosphoryl)-2-methylpropyl]caShow More⌵

Mol. Formula:
C37H53N6O8P

M.W.:
740.84

11 activity values

Type:
---

AlogP:
6.04

Polar Surface Area:
174.21

HBA:
11

HBD:
3

#RO5 Violations:
3

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5180728

Name:
tert-Butyl N-[(2S)-1-[(2S,4R)-2-{[1-(diphenoxyphosphoryl)-2-methylpropyl]caShow More⌵

Mol. Formula:
C37H53N6O8P

M.W.:
740.84

Type:
---

AlogP:
6.04

Polar Surface Area:
174.21

HBA:
11

HBD:
3

#RO5 Violations:
3

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5179147

Name:
tert-Butyl N-[(2S)-1-[(2S,4R)-2-{[1-(diphenoxyphosphoryl)-2-methylpropyl]caShow More⌵

Mol. Formula:
C35H49N6O8P

M.W.:
712.78

Type:
---

AlogP:
5.30

Polar Surface Area:
174.21

HBA:
11

HBD:
3

#RO5 Violations:
3

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA5176808

Name:
(3R,5S)-1-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3,3-dimethylbutanoyl]-5-{[Show More⌵

Mol. Formula:
C34H49N4O9P

M.W.:
688.76

6 activity values

Type:
---

AlogP:
4.85

Polar Surface Area:
175.59

HBA:
10

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA5169753

Name:
tert-Butyl N-[(2S)-1-[(2S,4S)-2-{[1-(diphenoxyphosphoryl)-2-methylpropyl]caShow More⌵

Mol. Formula:
C38H50N3O7P

M.W.:
691.81

8 activity values

Type:
---

AlogP:
7.76

Polar Surface Area:
123.27

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA4879313

Name:
benzyl (2S)-1-((2S)-2-(1-(diphenoxyphosphoryl)-2-methylpropylcarbamoyl)pyrrShow More⌵

Mol. Formula:
C35H44N3O7P

M.W.:
649.73

Type:
Unknown

AlogP:
6.77

Polar Surface Area:
123.27

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4878469

Name:
phenyl 1-(2-(1-(diphenoxyphosphoryl)-2-methylbutylamino)-2-oxoethyl)-2-oxo-Show More⌵

Mol. Formula:
C31H32N3O7P

M.W.:
589.59

Type:
Unknown

AlogP:
6.30

Polar Surface Area:
124.96

HBA:
8

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA4877732

Name:
tert-butyl 1-(1-(1-(diphenoxyphosphoryl)-2-methylpropylamino)-1-oxopropan-2Show More⌵

Mol. Formula:
C29H36N3O7P

M.W.:
569.60

Type:
Unknown

AlogP:
6.21

Polar Surface Area:
124.96

HBA:
8

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA4874616

Name:
diphenyl 1-((S)-1-((S)-2-(3-tert-butylureido)-3,3-dimethylbutanoyl)pyrrolidShow More⌵

Mol. Formula:
C33H49N4O6P

M.W.:
628.75

Type:
Unknown

AlogP:
6.33

Polar Surface Area:
126.07

HBA:
6

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA4874099

Name:
phenyl 1-(2-(1-(diphenoxyphosphoryl)-2-methylpropylamino)-2-oxoethyl)-2-oxoShow More⌵

Mol. Formula:
C30H30N3O7P

M.W.:
575.56

Type:
Unknown

AlogP:
5.91

Polar Surface Area:
124.96

HBA:
8

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4872003

Name:
diphenyl 1-((S)-1-((S)-3,3-dimethyl-2-pivalamidobutanoyl)pyrrolidine-2-carbShow More⌵

Mol. Formula:
C33H48N3O6P

M.W.:
613.74

Type:
Unknown

AlogP:
6.39

Polar Surface Area:
114.04

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA4864962

Name:
phenyl 1-(1-(1-(diphenoxyphosphoryl)-2-methylpropylamino)-1-oxopropan-2-yl)Show More⌵

Mol. Formula:
C31H32N3O7P

M.W.:
589.59

Type:
Unknown

AlogP:
6.47

Polar Surface Area:
124.96

HBA:
8

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA4856083

Name:
phenyl 1-(1-(1-(diphenoxyphosphoryl)-2-methylbutylamino)-1-oxopropan-2-yl)-Show More⌵

Mol. Formula:
C32H34N3O7P

M.W.:
603.61