Compounds

ALA5272495

Name:
4-(2-((3-chlorophenyl)amino)-2-oxoethyl)thiazole-2-carboxylic acid

Mol. Formula:
C12H9ClN2O3S

M.W.:
296.74

Type:
---

AlogP:
2.68

Polar Surface Area:
79.29

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA5271211

Name:
2-(2-acetamidothiazol-4-yl)-N-(3-chlorophenyl)acetamide

Mol. Formula:
C13H12ClN3O2S

M.W.:
309.78

Type:
---

AlogP:
2.94

Polar Surface Area:
71.09

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA5270880

Name:
N-(4-chlorophenyl)-2-(2-(cyclopropanesulfonamido)thiazol-4-yl)acetamide

Mol. Formula:
C14H14ClN3O3S2

M.W.:
371.87

Type:
---

AlogP:
2.88

Polar Surface Area:
88.16

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5270761

Name:
N-(3-chlorophenyl)-2-(2-(propylsulfonamido)thiazol-4-yl)acetamide

Mol. Formula:
C14H16ClN3O3S2

M.W.:
373.89

Type:
---

AlogP:
3.13

Polar Surface Area:
88.16

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5270312

Name:
N-(3-chlorophenyl)-2-(3-(methylsulfonamido)-1H-pyrazol-1-yl)acetamide

Mol. Formula:
C12H13ClN4O3S

M.W.:
328.78

Type:
---

AlogP:
1.55

Polar Surface Area:
93.09

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.87

DETAILS

ALA5270292

Name:
N-(3-chlorophenyl)-2-(2-((1-methylethyl)sulfonamido)thiazol-4-yl)acetamide

Mol. Formula:
C14H16ClN3O3S2

M.W.:
373.89

Type:
---

AlogP:
3.13

Polar Surface Area:
88.16

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5270156

Name:
N-([1,1'-biphenyl]-3-yl)-2-(2-(cyclopropanesulfonamido)thiazol-4-yl)acetamiShow More⌵

Mol. Formula:
C20H19N3O3S2

M.W.:
413.52

Type:
---

AlogP:
3.90

Polar Surface Area:
88.16

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5269282

Name:
N-(3-chlorophenyl)-2-(2-((2-methoxyethyl)sulfonamido)thiazol-4-yl)acetamide

Mol. Formula:
C14H16ClN3O4S2

M.W.:
389.89

Type:
---

AlogP:
2.37

Polar Surface Area:
97.39

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA5267968

Name:
2-(2-(cyclopropanesulfonamido)thiazol-4-yl)-N-(2-fluoro-4-(6-(trifluoromethShow More⌵

Mol. Formula:
C21H19F4N5O3S2

M.W.:
529.54

Type:
---

AlogP:
4.58

Polar Surface Area:
113.94

HBA:
7

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5280120

Name:
2-(2-(cyclopropanesulfonamido)thiazol-4-yl)-N-(4-(pyridin-4-yl)phenyl)acetaShow More⌵

Mol. Formula:
C19H18N4O3S2

M.W.:
414.51

Type:
---

AlogP:
3.29

Polar Surface Area:
101.05

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA5280009

Name:
2-(2-(cyclopropanesulfonamido)thiazol-4-yl)-N-(2-fluoro-4-(pyridin-3-yl)pheShow More⌵

Mol. Formula:
C21H21FN4O3S2

M.W.:
460.56

Type:
---

AlogP:
4.16

Polar Surface Area:
101.05

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5279838

Name:
N-(3-chlorophenyl)-2-(2-((1,1-dimethylethyl)sulfonamido)thiazol-4-yl)acetamShow More⌵

Mol. Formula:
C15H18ClN3O3S2

M.W.:
387.91

Type:
---

AlogP:
3.52

Polar Surface Area:
88.16

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5279706

Name:
2-(2-(cyclopropanesulfonamido)thiazol-4-yl)-N-(4-(pyridin-2-yl)phenyl)acetaShow More⌵

Mol. Formula:
C19H18N4O3S2

M.W.:
414.51

Type:
---

AlogP:
3.29

Polar Surface Area:
101.05

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA5279558

Name:
methyl 4-(((2,4,5-trichlorophenyl)sulfonyl)methanamido)thiophene-2-carboxylShow More⌵

Mol. Formula:
C13H8Cl3NO5S2

M.W.:
428.70

Type:
---

AlogP:
4.50

Polar Surface Area:
89.54

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5279495

Name:
N-(3-chlorophenyl)-2-(2-((trifluoromethyl)sulfonamido)thiazol-4-yl)acetamidShow More⌵

Mol. Formula:
C12H9ClF3N3O3S2

M.W.:
399.80

Type:
---

AlogP:
3.24

Polar Surface Area:
88.16

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5278356

Name:
2-(2-(cyclopropanesulfonamido)thiazol-4-yl)-N-(3-propoxyphenyl)acetamide

Mol. Formula:
C17H21N3O4S2

M.W.:
395.51

Type:
---

AlogP:
3.02

Polar Surface Area:
97.39

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA5275093

Name:
2-(2-(cyclopropanesulfonamido)thiazol-4-yl)-N-(4-propoxyphenyl)acetamide

Mol. Formula:
C17H21N3O4S2

M.W.:
395.51

Type:
---

AlogP:
3.02

Polar Surface Area:
97.39

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA5286545

Name:
N-(3-chlorophenyl)-2-(2-(N-methylmethylsulfonamido)thiazol-4-yl)acetamide

Mol. Formula:
C13H14ClN3O3S2

M.W.:
359.86

Type:
---

AlogP:
2.37

Polar Surface Area:
79.37

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA5285830

Name:
N-(3-chlorophenyl)-2-(4-(methylsulfonamido)-1H-imidazol-1-yl)acetamide

Mol. Formula:
C12H13ClN4O3S

M.W.:
328.78

Type:
---

AlogP:
1.55

Polar Surface Area:
93.09

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.87

DETAILS

ALA5284514

Name:
N-(3-chlorophenyl)-2-(2-(cyclopropanesulfonamido)thiazol-4-yl)-N-methylacetShow More⌵

Mol. Formula:
C15H16ClN3O3S2

M.W.:
385.90

Type:
---

AlogP:
2.91

Polar Surface Area:
79.37

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.83

DETAILS