Compounds

ALA4879080

Name:
7-((3,5-Dimethoxyphenyl)amino)-5-((3-methacrylamidobenzyl)amino)imidazo[1,2Show More⌵

Mol. Formula:
C26H27N7O4

M.W.:
501.55

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.72

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA4878313

Name:
5-((3-(2-Chloroacetamido)benzyl)amino)-7-((4-morpholinophenyl)amino)imidazoShow More⌵

Mol. Formula:
C26H27ClN8O3

M.W.:
535.01

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.20

Polar Surface Area:
138.91

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA4877887

Name:
5-((3-(but-2-Ynamido)benzyl)amino)-7-((3,5-dimethoxyphenyl)amino)imidazo[1,Show More⌵

Mol. Formula:
C26H25N7O4

M.W.:
499.53

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.16

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA4874902

Name:
5-((4-Acrylamidobenzyl)amino)-7-((3,5-dimethoxyphenyl)amino)imidazo[1,2-c]pShow More⌵

Mol. Formula:
C25H25N7O4

M.W.:
487.52

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.33

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA4873050

Name:
5-((4-(2-Chloroacetamido)benzyl)amino)-7-((3,5-dimethoxyphenyl)amino)imidazShow More⌵

Mol. Formula:
C24H24ClN7O4

M.W.:
509.95

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.38

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA4870058

Name:
5-((3-(Acrylamidomethyl)benzyl)amino)-7-((3,5-dimethoxyphenyl)amino)imidazoShow More⌵

Mol. Formula:
C26H27N7O4

M.W.:
501.55

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.00

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA4865278

Name:
5-(((1-Acryloylpyrrolidin-3-yl)methyl)amino)-7-((3,5-dimethoxyphenyl)amino)Show More⌵

Mol. Formula:
C23H27N7O4

M.W.:
465.51

2 activity values

2 unique targets

Type:
Unknown

AlogP:
2.04

Polar Surface Area:
136.11

HBA:
9

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA4865134

Name:
5-((4-Acrylamidophenethyl)amino)-7-((3,5-dimethoxyphenyl)amino)imidazo[1,2-Show More⌵

Mol. Formula:
C26H27N7O4

M.W.:
501.55

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.37

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA4864268

Name:
5-((3-Actylamidopropyl)amino)-7-((3,5-dimethoxyphenyl)amino)imidazo[1,2-c]pShow More⌵

Mol. Formula:
C21H25N7O4

M.W.:
439.48

2 activity values

2 unique targets

Type:
Unknown

AlogP:
1.69

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA4858740

Name:
(E)-7-((3,5-Dimethoxyphenyl)amino)-5-((3-(4-(dimethylamino)but-2-enamido)beShow More⌵

Mol. Formula:
C28H32N8O4

M.W.:
544.62

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.26

Polar Surface Area:
148.14

HBA:
10

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA4858416

Name:
5-(((1-Acryloylpiperidin-4-yl)methyl)amino)-7-((3,5-dimethoxyphenyl)amino)iShow More⌵

Mol. Formula:
C24H29N7O4

M.W.:
479.54

2 activity values

2 unique targets

Type:
Unknown

AlogP:
2.43

Polar Surface Area:
136.11

HBA:
9

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4855263

Name:
5-((3-Acrylamidobenzyl)amino)-7-((3,5-dimethoxyphenyl)amino)imidazo[1,2-c]pShow More⌵

Mol. Formula:
C25H25N7O4

M.W.:
487.52

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.33

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA4853489

Name:
5-((3-(2-Chloroacetamido)benzyl)amino)-7-((4-(dimethylamino)phenyl)amino)imShow More⌵

Mol. Formula:
C24H25ClN8O2

M.W.:
492.97

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.43

Polar Surface Area:
129.68

HBA:
8

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA4851056

Name:
5-((3-Acrylamidophenethyl)amino)-7-((3,5-dimethoxyphenyl)amino)imidazo[1,2-Show More⌵

Mol. Formula:
C26H27N7O4

M.W.:
501.55

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.37

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA4850367

Name:
7-((3,5-Dimethoxyphenyl)amino)-5-((3-propiolamidobenzyl)amino)imidazo[1,2-cShow More⌵

Mol. Formula:
C25H23N7O4

M.W.:
485.50

2 activity values

2 unique targets

Type:
Unknown

AlogP:
2.77

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA4849832

Name:
7-((3,5-Dimethoxyphenyl)amino)-5-((3-propionamidobenzyl)amino)imidazo[1,2-cShow More⌵

Mol. Formula:
C25H27N7O4

M.W.:
489.54

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.55

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA4849602

Name:
5-((4-(Acrylaminomethyl)benzyl)amino)-7-((3,5-dimethoxyphenyl)amino)imidazoShow More⌵

Mol. Formula:
C26H27N7O4

M.W.:
501.55

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.00

Polar Surface Area:
144.90

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA4848732

Name:
5-((3-(2-Chloroacetamido)benzyl)amino)-7-((4-(4-methylpiperazin-1-yl)phenylShow More⌵

Mol. Formula:
C27H30ClN9O2

M.W.:
548.05

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.11

Polar Surface Area:
132.92

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA4847791

Name:
5-(((1-Acryloylpiperidin-3-yl)methyl)amino)-7-((3,5-dimethoxyphenyl)amino)iShow More⌵

Mol. Formula:
C24H29N7O4

M.W.:
479.54

2 activity values

2 unique targets

Type:
Unknown

AlogP:
2.43

Polar Surface Area:
136.11

HBA:
9

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4845881

Name:
5-((3-(2-Chloroacetamido)benzyl)amino)-7-((4-(4-methyl-1,4-diazepan-1-yl)phShow More⌵

Mol. Formula:
C28H32ClN9O2

M.W.:
562.08

2 activity values

2 unique targets

Type:
Unknown

AlogP:
3.50

Polar Surface Area:
132.92

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.23

DETAILS