Compounds

ALA5269179

Name:
3-(5-fluoro-3-methylbenzo[b]thiophen-2-yl)-2,6-dimethyl-8-(pentan-3-yl)imidShow More⌵

Mol. Formula:
C22H24FN3S

M.W.:
381.52

Type:
---

AlogP:
6.58

Polar Surface Area:
30.19

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5280146

Name:
N,N-diethyl-3-(5-fluoro-3-methylbenzo[b]thiophen-2-yl)-2,6-dimethylimidazo[Show More⌵

Mol. Formula:
C21H23FN4S

M.W.:
382.51

Type:
---

AlogP:
5.52

Polar Surface Area:
33.43

HBA:
5

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA4593848

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-N7-(4-methoxyphenyl)-1-methyl-N7-(1-Show More⌵

Mol. Formula:
C26H29ClN4O2

M.W.:
465.00

6 activity values

3 unique targets

Type:
Unknown

AlogP:
6.84

Polar Surface Area:
51.55

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.32

DETAILS

ALA4592625

Name:
N-[2-[(4-Chloro-2-methoxy-6-methylphenyl)amino]-1-methyl-1H-benzimidazol-7-Show More⌵

Mol. Formula:
C24H23Cl3N4O2

M.W.:
505.83

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.63

Polar Surface Area:
59.39

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4591720

Name:
3-[[2-[(4-Bromo-2-methoxy-6-methylphenyl)amino]-1-methyl-1H-benzimidazol-7-Show More⌵

Mol. Formula:
C26H28BrN5O2

M.W.:
522.45

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.04

Polar Surface Area:
85.41

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA4591335

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-N7-(4-chlorophenyl)-1-methyl-N7-(1-mShow More⌵

Mol. Formula:
C25H26Cl2N4O

M.W.:
469.42

1 activity values

1 unique targets

Type:
Unknown

AlogP:
7.49

Polar Surface Area:
42.32

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.32

DETAILS

ALA4588387

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-1-methyl-N7-(1-methylethyl)-N7-[4-(1Show More⌵

Mol. Formula:
C28H33ClN4O2

M.W.:
493.05

1 activity values

1 unique targets

Type:
Unknown

AlogP:
7.62

Polar Surface Area:
51.55

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA4581950

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-1-methyl-N7-(1-methylethyl)-N7-phenyShow More⌵

Mol. Formula:
C25H27ClN4O

M.W.:
434.97

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.83

Polar Surface Area:
42.32

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4580457

Name:
3-[[2-[(4-Bromo-2-methoxy-6-methylphenyl)amino]-1-methyl-1H-benzimidazol-7-Show More⌵

Mol. Formula:
C27H30BrN5O2

M.W.:
536.47

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.30

Polar Surface Area:
71.42

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4569860

Name:
N2-(4-Bromo-2-methoxy-6-methylphenyl)-1-methyl-N7-(1-methylethyl)-N7-[4-(meShow More⌵

Mol. Formula:
C26H29BrN4O3S

M.W.:
557.51

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.35

Polar Surface Area:
76.46

HBA:
7

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4566348

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-N7-(4-chlorophenyl)-N7-(2,2-dimethylShow More⌵

Mol. Formula:
C27H31Cl3N4O

M.W.:
533.93

1 activity values

1 unique targets

Type:
Unknown

AlogP:
8.12

Polar Surface Area:
42.32

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4556873

Name:
4-[[2-[(4-Bromo-2-methoxy-6-methylphenyl)amino]-1-methyl-1H-benzimidazol-7-Show More⌵

Mol. Formula:
C26H26BrN5O

M.W.:
504.43

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.81

Polar Surface Area:
66.11

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA4547748

Name:
N2-(4-Bromo-2-methoxy-6-methylphenyl)-N7-(3-methoxyphenyl)-1-methyl-N7-(1-mShow More⌵

Mol. Formula:
C26H29BrN4O2

M.W.:
509.45

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.95

Polar Surface Area:
51.55

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4544244

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-N7-(6-methoxypyridin-3-yl)-1-methyl-Show More⌵

Mol. Formula:
C25H28ClN5O2

M.W.:
465.99

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.24

Polar Surface Area:
64.44

HBA:
7

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.35

DETAILS

ALA4540030

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-N7-(4-chlorophenyl)-N7-(2-methoxyethShow More⌵

Mol. Formula:
C25H27Cl3N4O2

M.W.:
521.88

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.73

Polar Surface Area:
51.55

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA4538409

Name:
3-[[2-[(4-Bromo-2-methoxy-6-methylphenyl)amino]-1-methyl-1H-benzimidazol-7-Show More⌵

Mol. Formula:
C26H26BrN5O

M.W.:
504.43

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.81

Polar Surface Area:
66.11

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA4527586

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-1-methyl-N7-(1-methylethyl)-N7-(5-meShow More⌵

Mol. Formula:
C25H28ClN5O

M.W.:
449.99

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.54

Polar Surface Area:
55.21

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4526475

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-N7-(4-chlorophenyl)-1-methyl-N7-(tetShow More⌵

Mol. Formula:
C27H28Cl2N4O2

M.W.:
511.45

1 activity values

1 unique targets

Type:
Unknown

AlogP:
7.12

Polar Surface Area:
51.55

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4526083

Name:
2-[3-[[2-[(4-Bromo-2-methoxy-6-methylphenyl)amino]-1-methyl-1H-benzimidazolShow More⌵

Mol. Formula:
C29H34BrN5O2

M.W.:
564.53

1 activity values

1 unique targets

Type:
Unknown

AlogP:
6.71

Polar Surface Area:
85.41

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA4524490

Name:
N2-(4-Chloro-2-methoxy-6-methylphenyl)-1-methyl-N7-(1-methylethyl)-N7-[3-(1Show More⌵

Mol. Formula:
C28H33ClN4O2

M.W.:
493.05

1 activity values

1 unique targets

Type:
Unknown

AlogP:
7.62

Polar Surface Area:
51.55

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.27

DETAILS