Compounds

ALA5272486

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-hydroxyphenyl)piperidin-1-yl)-2Show More⌵

Mol. Formula:
C22H27FN2O3

M.W.:
386.47

Type:
---

AlogP:
2.37

Polar Surface Area:
64.01

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.83

DETAILS

ALA5272258

Name:
2-(4-chlorophenyl)-1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-hydroxyphenyShow More⌵

Mol. Formula:
C22H27ClN2O3

M.W.:
402.92

Type:
---

AlogP:
2.89

Polar Surface Area:
64.01

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5272171

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-hydroxyphenyl)piperidin-1-yl)-2Show More⌵

Mol. Formula:
C23H27F3N2O4

M.W.:
452.47

Type:
---

AlogP:
3.13

Polar Surface Area:
73.24

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5271628

Name:
(3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)(1-pShow More⌵

Mol. Formula:
C28H38N2O3

M.W.:
450.62

Type:
---

AlogP:
4.20

Polar Surface Area:
53.01

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA5271351

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2Show More⌵

Mol. Formula:
C21H28N2O3S

M.W.:
388.53

Type:
---

AlogP:
2.60

Polar Surface Area:
53.01

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.83

DETAILS

ALA5270915

Name:
2-(3-chlorophenyl)-1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-hydroxyphenyShow More⌵

Mol. Formula:
C22H27ClN2O3

M.W.:
402.92

Type:
---

AlogP:
2.89

Polar Surface Area:
64.01

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5270488

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-phenylpiperidin-1-yl)-2-phenylethaShow More⌵

Mol. Formula:
C22H28N2O2

M.W.:
352.48

Type:
---

AlogP:
2.53

Polar Surface Area:
43.78

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA5269806

Name:
2-(3-bromophenyl)-1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenylShow More⌵

Mol. Formula:
C23H29BrN2O3

M.W.:
461.40

Type:
---

AlogP:
3.30

Polar Surface Area:
53.01

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA5269558

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-hydroxyphenyl)piperidin-1-yl)-2Show More⌵

Mol. Formula:
C23H27F3N2O4

M.W.:
452.47

Type:
---

AlogP:
3.13

Polar Surface Area:
73.24

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5268998

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2Show More⌵

Mol. Formula:
C25H34N2O3

M.W.:
410.56

Type:
---

AlogP:
3.27

Polar Surface Area:
53.01

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5268021

Name:
1-((3S,4R)-3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidinShow More⌵

Mol. Formula:
C23H27F3N2O3

M.W.:
436.47

Type:
---

AlogP:
2.95

Polar Surface Area:
53.01

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5282507

Name:
(3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)(1-pShow More⌵

Mol. Formula:
C27H36N2O3

M.W.:
436.60

Type:
---

AlogP:
3.80

Polar Surface Area:
53.01

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA5281864

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-hydroxyphenyl)piperidin-1-yl)-2Show More⌵

Mol. Formula:
C23H30N2O3

M.W.:
382.50

Type:
---

AlogP:
2.54

Polar Surface Area:
64.01

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.83

DETAILS

ALA5281561

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-hydroxyphenyl)piperidin-1-yl)-2Show More⌵

Mol. Formula:
C22H27FN2O3

M.W.:
386.47

Type:
---

AlogP:
2.37

Polar Surface Area:
64.01

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.83

DETAILS

ALA5281114

Name:
2-(3-chlorophenyl)-1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyShow More⌵

Mol. Formula:
C23H29ClN2O3

M.W.:
416.95

Type:
---

AlogP:
3.19

Polar Surface Area:
53.01

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5281054

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-hydroxyphenyl)piperidin-1-yl)-3Show More⌵

Mol. Formula:
C24H29F3N2O3

M.W.:
450.50

Type:
---

AlogP:
3.64

Polar Surface Area:
64.01

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5278225

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2Show More⌵

Mol. Formula:
C23H29FN2O3

M.W.:
400.49

Type:
---

AlogP:
2.67

Polar Surface Area:
53.01

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5277743

Name:
3-((dimethylamino)methyl)-4-(3-methoxyphenyl)-1-(3-(trifluoromethyl)phenethShow More⌵

Mol. Formula:
C24H31F3N2O2

M.W.:
436.52

Type:
---

AlogP:
4.03

Polar Surface Area:
35.94

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5277326

Name:
3-((dimethylamino)methyl)-4-(3-hydroxyphenyl)-1-(3-(trifluoromethyl)phenethShow More⌵

Mol. Formula:
C23H29F3N2O2

M.W.:
422.49

Type:
---

AlogP:
3.72

Polar Surface Area:
46.94

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5277164

Name:
1-(3-((dimethylamino)methyl)-4-hydroxy-4-(3-hydroxyphenyl)piperidin-1-yl)-2Show More⌵

Mol. Formula:
C23H27F3N2O4

M.W.:
452.47

Type:
---

AlogP:
3.13

Polar Surface Area:
73.24

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.70

DETAILS