Compounds

ALA5272638

Name:
N-(5-(1-Methyl-1H-benzo[d]imidazol-7-yl)-1H-pyrazol-3-yl)-4-((1-methylpiperShow More⌵

Mol. Formula:
C24H27N7O

M.W.:
429.53

Type:
---

AlogP:
3.72

Polar Surface Area:
90.87

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5272321

Name:
N-(5-(1-(2-Fluorobenzyl)-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-3-yl)-4-((1-mShow More⌵

Mol. Formula:
C30H30FN7O

M.W.:
523.62

Type:
---

AlogP:
5.37

Polar Surface Area:
90.87

HBA:
6

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA5272203

Name:
4-[2-(3H-benzimidazol-5-ylamino)quinazolin-5-yl]oxycyclohexanol

Mol. Formula:
C21H21N5O2

M.W.:
375.43

Type:
---

AlogP:
3.93

Polar Surface Area:
95.95

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5271605

Name:
1-(4-aminophenyl)-7-((5-(4-isopropylpiperazin-1-yl)-4-methylpyridin-2-yl)amShow More⌵

Mol. Formula:
C26H30N8O

M.W.:
470.58

Type:
---

AlogP:
3.34

Polar Surface Area:
105.20

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5271010

Name:
1-(4-(aminomethyl)phenyl)-7-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)Show More⌵

Mol. Formula:
C24H26N8O

M.W.:
442.53

Type:
---

AlogP:
2.13

Polar Surface Area:
105.20

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5270966

Name:
4-((1-Methylpiperidin-4-yl)amino)-N-(5-(1-(tetrahydro-2H-pyran-4-yl)-1H-benShow More⌵

Mol. Formula:
C28H33N7O2

M.W.:
499.62

Type:
---

AlogP:
4.54

Polar Surface Area:
100.10

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA5270690

Name:
N-(5-(1-Benzyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-3-yl)-3-fluoro-4-((1-meShow More⌵

Mol. Formula:
C30H30FN7O

M.W.:
523.62

Type:
---

AlogP:
5.37

Polar Surface Area:
90.87

HBA:
6

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA5270580

Name:
N-(5-(1-(4-Chlorobenzyl)-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-3-yl)-4-((1-mShow More⌵

Mol. Formula:
C30H30ClN7O

M.W.:
540.07

Type:
---

AlogP:
5.89

Polar Surface Area:
90.87

HBA:
6

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5270170

Name:
1-(4-aminophenyl)-7-((4-methyl-5-((1-methylpiperidin-4-yl)amino)pyridin-2-yShow More⌵

Mol. Formula:
C25H28N8O

M.W.:
456.55

Type:
---

AlogP:
3.32

Polar Surface Area:
113.99

HBA:
9

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA5268304

Name:
1-(4-aminophenyl)-7-((5-(4-ethylpiperazin-1-yl)-4-methylpyridin-2-yl)amino)Show More⌵

Mol. Formula:
C25H28N8O

M.W.:
456.55

Type:
---

AlogP:
2.95

Polar Surface Area:
105.20

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5267748

Name:
N-(5-(1-(3-Chlorobenzyl)-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-3-yl)-4-((1-mShow More⌵

Mol. Formula:
C30H30ClN7O

M.W.:
540.07

Type:
---

AlogP:
5.89

Polar Surface Area:
90.87

HBA:
6

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5282636

Name:
1-(4-aminophenyl)-7-((5-(4-aminopiperidin-1-yl)-4-methylpyridin-2-yl)amino)Show More⌵

Mol. Formula:
C24H26N8O

M.W.:
442.53

Type:
---

AlogP:
2.74

Polar Surface Area:
127.98

HBA:
9

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5282407

Name:
N-(4-(7-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-2-oxopyrido[3,4-b]pShow More⌵

Mol. Formula:
C24H26N8O3S

M.W.:
506.59

Type:
---

AlogP:
2.04

Polar Surface Area:
125.35

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5281795

Name:
N-(5-(1-Benzyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-3-yl)-benzamide

Mol. Formula:
C24H19N5O

M.W.:
393.45

Type:
---

AlogP:
4.73

Polar Surface Area:
75.60

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5280904

Name:
1-(3-aminophenyl)-7-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[3Show More⌵

Mol. Formula:
C23H24N8O

M.W.:
428.50

Type:
---

AlogP:
2.25

Polar Surface Area:
105.20

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5280468

Name:
N-(5-(1-Benzyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-3-yl)-2-methyl-4-((1-meShow More⌵

Mol. Formula:
C31H33N7O

M.W.:
519.65

Type:
---

AlogP:
5.54

Polar Surface Area:
90.87

HBA:
6

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA5280424

Name:
N-(5-(1-(2-Chlorobenzyl)-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-3-yl)-4-((1-mShow More⌵

Mol. Formula:
C30H30ClN7O

M.W.:
540.07

Type:
---

AlogP:
5.89

Polar Surface Area:
90.87

HBA:
6

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5280266

Name:
N-(5-(1-Benzyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-3-yl)-1-methylpiperidinShow More⌵

Mol. Formula:
C24H26N6O

M.W.:
414.51

Type:
---

AlogP:
3.76

Polar Surface Area:
78.84

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5279939

Name:
1-(4-(dimethylamino)phenyl)-7-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)aminShow More⌵

Mol. Formula:
C25H28N8O

M.W.:
456.55

Type:
---

AlogP:
2.74

Polar Surface Area:
82.42

HBA:
9

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA5279911

Name:
N-(5-(1-Cyclopropyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-3-yl)-4-((1-methylShow More⌵

Mol. Formula:
C26H29N7O

M.W.:
455.57

Type:
---

AlogP:
4.52

Polar Surface Area:
90.87

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.40

DETAILS