Compounds

ALA5267449

Name:
6-(cyclopropanecarbonylamino)-4-[3-[[4-(1,1-dioxothiazinan-2-yl)phenyl]carbShow More⌵

Mol. Formula:
C28H31N7O6S

M.W.:
596.68

Type:
---

AlogP:
3.12

Polar Surface Area:
171.72

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA5266772

Name:
6-(cyclopropanecarbonylamino)-4-[3-[[4-(5-fluoro-6-oxo-1H-pyridin-2-yl)phenShow More⌵

Mol. Formula:
C29H26FN7O5

M.W.:
574.59

Type:
---

AlogP:
3.68

Polar Surface Area:
167.20

HBA:
8

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA5266102

Name:
6-(5-(10-((S)-1-((2S,4R)-4-hydroxy-2-(4-(4-methylthiazol-5-yl)benzylcarbamoShow More⌵

Mol. Formula:
C54H69N11O8S

M.W.:
1032.28

Type:
---

AlogP:
---

Polar Surface Area:
---

HBA:
---

HBD:
---

#RO5 Violations:
na

#Rotatable Bonds:
---

Passes Ro3:
---

QED Weighted:
---

DETAILS

ALA5282623

Name:
6-[(5-fluoro-2-pyridyl)amino]-4-[2-methoxy-3-[[4-(2-oxo-1-piperidyl)phenyl]Show More⌵

Mol. Formula:
C30H29FN8O4

M.W.:
587.63

Type:
---

AlogP:
4.64

Polar Surface Area:
150.47

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA5282377

Name:
6-(cyclopropanecarbonylamino)-4-[3-[[4-(1-ethyl-1,2,4-triazol-3-yl)phenyl]cShow More⌵

Mol. Formula:
C28H29N9O4

M.W.:
558.62

Type:
---

AlogP:
3.47

Polar Surface Area:
165.05

HBA:
10

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA5281991

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[4-(2-oxoazepan-1-yl)phenyl]cShow More⌵

Mol. Formula:
C30H33N7O5

M.W.:
574.66

Type:
---

AlogP:
4.10

Polar Surface Area:
154.65

HBA:
8

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA5280466

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[4-(2-oxopyrrolidin-1-yl)phenShow More⌵

Mol. Formula:
C28H29N7O5

M.W.:
546.60

Type:
---

AlogP:
3.32

Polar Surface Area:
154.65

HBA:
8

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.32

DETAILS

ALA5278999

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[(4-pyrazol-1-ylphenyl)carbamoShow More⌵

Mol. Formula:
C27H26N8O4

M.W.:
529.58

Type:
---

AlogP:
3.37

Polar Surface Area:
152.16

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA5278635

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[3-(2-oxo-1-pyridyl)phenyl]caShow More⌵

Mol. Formula:
C29H27N7O5

M.W.:
556.60

Type:
---

AlogP:
3.34

Polar Surface Area:
156.34

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5273814

Name:
4-[2-methoxy-3-[[4-(2-oxo-1-piperidyl)phenyl]carbamoyl]anilino]-6-(2-pyridyShow More⌵

Mol. Formula:
C30H30N8O4

M.W.:
569.64

Type:
---

AlogP:
4.50

Polar Surface Area:
150.47

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA5273136

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[4-(1-piperidyl)phenyl]carbamShow More⌵

Mol. Formula:
C29H33N7O4

M.W.:
546.65

Type:
---

AlogP:
4.18

Polar Surface Area:
137.58

HBA:
8

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.32

DETAILS

ALA5291007

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[4-(3-pyridyl)phenyl]carbamoyShow More⌵

Mol. Formula:
C29H27N7O4

M.W.:
540.60

Type:
---

AlogP:
4.25

Polar Surface Area:
147.23

HBA:
8

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5289104

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[4-(6-oxo-1H-pyridin-2-yl)pheShow More⌵

Mol. Formula:
C29H27N7O5

M.W.:
556.60

Type:
---

AlogP:
3.54

Polar Surface Area:
167.20

HBA:
8

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA5286565

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[4-(2-oxo-3-piperidyl)phenyl]Show More⌵

Mol. Formula:
C29H31N7O5

M.W.:
560.63

Type:
---

AlogP:
3.18

Polar Surface Area:
163.44

HBA:
8

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA5285091

Name:
4-[3-[[4-(cyclopentanecarbonylamino)phenyl]carbamoyl]-2-methoxy-anilino]-6-Show More⌵

Mol. Formula:
C30H33N7O5

M.W.:
574.66

Type:
---

AlogP:
4.32

Polar Surface Area:
163.44

HBA:
8

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.24

DETAILS

ALA5284638

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[4-(2-oxo-1-pyridyl)phenyl]caShow More⌵

Mol. Formula:
C29H27N7O5

M.W.:
556.60

Type:
---

AlogP:
3.34

Polar Surface Area:
156.34

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5284232

Name:
6-(cyclopropanecarbonylamino)-4-[3-[(4-imidazol-1-ylphenyl)carbamoyl]-2-metShow More⌵

Mol. Formula:
C27H26N8O4

M.W.:
529.58

Type:
---

AlogP:
3.37

Polar Surface Area:
152.16

HBA:
9

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA5270823

Name:
6-(cyclopropanecarbonylamino)-4-[3-[[2-fluoro-4-(2-oxo-1-piperidyl)phenyl]cShow More⌵

Mol. Formula:
C29H30FN7O5

M.W.:
578.62

Type:
---

AlogP:
3.85

Polar Surface Area:
154.65

HBA:
8

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA5269164

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[4-(1-methyl-1,2,4-triazol-3-Show More⌵

Mol. Formula:
C27H27N9O4

M.W.:
544.59

Type:
---

AlogP:
2.98

Polar Surface Area:
165.05

HBA:
10

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5268371

Name:
6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-[[4-(2-oxo-1-piperidyl)phenyl]Show More⌵

Mol. Formula:
C29H31N7O5

M.W.:
560.63

Type:
---

AlogP:
3.71

Polar Surface Area:
154.65

HBA:
8

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.31

DETAILS