Compounds

ALA5271103

Name:
N-(5-(pyridin-3-yl)-1H-indazol-3-yl)benzamide

Mol. Formula:
C19H14N4O

M.W.:
314.35

Type:
---

AlogP:
3.88

Polar Surface Area:
70.67

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5270227

Name:
(R)-N-(5-(5-(2-amino-3-phenylpropanamido)pyridin-3-yl)-1H-indazol-3-yl)benzShow More⌵

Mol. Formula:
C28H24N6O2

M.W.:
476.54

Type:
---

AlogP:
4.39

Polar Surface Area:
125.79

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA5270192

Name:
N-(5-(5-((2-hydroxyethyl)amino)pyridin-3-yl)-1H-indazol-3-yl)benzamide

Mol. Formula:
C21H19N5O2

M.W.:
373.42

Type:
---

AlogP:
3.28

Polar Surface Area:
102.93

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5270145

Name:
(R)-N-(5-(5-(2-amino-2-phenylacetamido)pyridin-3-yl)-1H-indazol-3-yl)benzamShow More⌵

Mol. Formula:
C27H22N6O2

M.W.:
462.51

Type:
---

AlogP:
4.52

Polar Surface Area:
125.79

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA5269885

Name:
(S)-4-acrylamido-N-(5-(5-((1-hydroxy-3-phenylpropan-2-yl)amino)pyridin-3-ylShow More⌵

Mol. Formula:
C31H28N6O3

M.W.:
532.60

Type:
---

AlogP:
5.02

Polar Surface Area:
132.03

HBA:
6

HBD:
5

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.16

DETAILS

ALA5268968

Name:
(S)-N-(5-(5-((3-hydroxy-2-phenylpropyl)amino)pyridin-3-yl)-1H-indazol-3-yl)Show More⌵

Mol. Formula:
C28H25N5O2

M.W.:
463.54

Type:
---

AlogP:
5.07

Polar Surface Area:
102.93

HBA:
5

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA5281785

Name:
(R)-N-(5-(5-((2-hydroxy-2-phenylethyl)amino)pyridin-3-yl)-1H-indazol-3-yl)bShow More⌵

Mol. Formula:
C27H23N5O2

M.W.:
449.51

Type:
---

AlogP:
5.02

Polar Surface Area:
102.93

HBA:
5

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA5280467

Name:
(R)-N-(5-(5-((3-hydroxy-2-phenylpropyl)amino)pyridin-3-yl)-1H-indazol-3-yl)Show More⌵

Mol. Formula:
C28H25N5O2

M.W.:
463.54

Type:
---

AlogP:
5.07

Polar Surface Area:
102.93

HBA:
5

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA5278281

Name:
5-(3-benzamido-1H-indazol-5-yl)-N-methylnicotinamide

Mol. Formula:
C21H17N5O2

M.W.:
371.40

Type:
---

AlogP:
3.24

Polar Surface Area:
99.77

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5277284

Name:
(S)-4-acrylamido-N-(5-(5-(2-amino-2-phenylacetamido)pyridin-3-yl)-1H-indazoShow More⌵

Mol. Formula:
C30H25N7O3

M.W.:
531.58

Type:
---

AlogP:
4.64

Polar Surface Area:
154.89

HBA:
6

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.18

DETAILS

ALA5277013

Name:
(S)-N-(5-(5-(2-amino-3-phenylpropanamido)pyridin-3-yl)-1H-indazol-3-yl)benzShow More⌵

Mol. Formula:
C28H24N6O2

M.W.:
476.54

Type:
---

AlogP:
4.39

Polar Surface Area:
125.79

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA5276424

Name:
(S)-N-(5-(5-((2-hydroxy-2-phenylethyl)amino)pyridin-3-yl)-1H-indazol-3-yl)bShow More⌵

Mol. Formula:
C27H23N5O2

M.W.:
449.51

Type:
---

AlogP:
5.02

Polar Surface Area:
102.93

HBA:
5

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA5274920

Name:
(S)-4-acrylamido-N-(5-(5-(2-amino-3-phenylpropanamido)pyridin-3-yl)-1H-indaShow More⌵

Mol. Formula:
C31H27N7O3

M.W.:
545.60

Type:
---

AlogP:
4.51

Polar Surface Area:
154.89

HBA:
6

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.17

DETAILS

ALA5274271

Name:
N-(5-(5-(2-aminoethoxy)pyridin-3-yl)-1H-indazol-3-yl)benzamide

Mol. Formula:
C21H19N5O2

M.W.:
373.42

Type:
---

AlogP:
3.21

Polar Surface Area:
105.92

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5273413

Name:
(S)-4-acrylamido-N-(5-(5-((2-hydroxy-1-phenylethyl)amino)pyridin-3-yl)-1H-iShow More⌵

Mol. Formula:
C30H26N6O3

M.W.:
518.58

Type:
---

AlogP:
5.15

Polar Surface Area:
132.03

HBA:
6

HBD:
5

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.17

DETAILS

ALA5287087

Name:
N-(5-(5-((2-aminoethyl)amino)pyridin-3-yl)-1H-indazol-3-yl)benzamide

Mol. Formula:
C21H20N6O

M.W.:
372.43

Type:
---

AlogP:
3.25

Polar Surface Area:
108.72

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5287079

Name:
(S)-N-(5-(5-(2-amino-2-phenylethoxy)pyridin-3-yl)-1H-indazol-3-yl)benzamide

Mol. Formula:
C27H23N5O2

M.W.:
449.51

Type:
---

AlogP:
4.96

Polar Surface Area:
105.92

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA5286971

Name:
N-(5-(5-methoxypyridin-3-yl)-1H-indazol-3-yl)benzamide

Mol. Formula:
C20H16N4O2

M.W.:
344.37

Type:
---

AlogP:
3.89

Polar Surface Area:
79.90

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5286683

Name:
(R)-4-acrylamido-N-(5-(5-((2-hydroxy-2-phenylethyl)amino)pyridin-3-yl)-1H-iShow More⌵

Mol. Formula:
C30H26N6O3

M.W.:
518.58

Type:
---

AlogP:
5.15

Polar Surface Area:
132.03

HBA:
6

HBD:
5

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.17

DETAILS

ALA5285145

Name:
(R)-N-(5-(5-(2-amino-3-phenylpropoxy)pyridin-3-yl)-1H-indazol-3-yl)benzamidShow More⌵

Mol. Formula:
C28H25N5O2

M.W.:
463.54

Type:
---

AlogP:
4.83

Polar Surface Area:
105.92

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.31

DETAILS