Compounds

ALA5269382

Name:
1-(3-chloro-2-pyridyl)-4-(4-methyl-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C17H12ClN5

M.W.:
321.77

Type:
---

AlogP:
3.84

Polar Surface Area:
56.49

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5269068

Name:
5-[1-(4-fluorophenyl)pyrazolo[3,4-b]pyridin-4-yl]-N-(2,2,2-trifluoroethyl)pShow More⌵

Mol. Formula:
C18H12F4N6

M.W.:
388.33

Type:
---

AlogP:
3.99

Polar Surface Area:
68.52

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5267919

Name:
4-(4-methyl-3-pyridyl)-1-(2,2,2-trifluoroethyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C14H11F3N4

M.W.:
292.26

Type:
---

AlogP:
3.36

Polar Surface Area:
43.60

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5282733

Name:
1-methyl-4-(4-methyl-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C13H12N4

M.W.:
224.27

Type:
---

AlogP:
2.34

Polar Surface Area:
43.60

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA5282485

Name:
5-[1-(2,4-difluorophenyl)pyrazolo[3,4-b]pyridin-4-yl]pyrimidin-4-amine

Mol. Formula:
C16H10F2N6

M.W.:
324.29

Type:
---

AlogP:
2.74

Polar Surface Area:
82.51

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5280658

Name:
4-(4-methyl-3-pyridyl)-7-phenyl-pyrrolo[1,2-b]pyridazine

Mol. Formula:
C19H15N3

M.W.:
285.35

Type:
---

AlogP:
4.37

Polar Surface Area:
30.19

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5278719

Name:
1-[(4-fluorophenyl)methyl]-4-(4-methyl-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C19H15FN4

M.W.:
318.36

Type:
---

AlogP:
3.99

Polar Surface Area:
43.60

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5278006

Name:
1-(4-fluorophenyl)-4-(4-methylpyrimidin-5-yl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C17H12FN5

M.W.:
305.32

Type:
---

AlogP:
3.33

Polar Surface Area:
56.49

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5277196

Name:
1-(2-methoxyphenyl)-4-(4-methyl-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C19H16N4O

M.W.:
316.36

Type:
---

AlogP:
3.80

Polar Surface Area:
52.83

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5276695

Name:
3-[4-(4-aminopyrimidin-5-yl)pyrazolo[3,4-b]pyridin-1-yl]benzenesulfonamide

Mol. Formula:
C16H13N7O2S

M.W.:
367.39

Type:
---

AlogP:
1.11

Polar Surface Area:
142.67

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5276101

Name:
1-tert-butyl-4-(4-methyl-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C16H18N4

M.W.:
266.35

Type:
---

AlogP:
3.56

Polar Surface Area:
43.60

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA5275896

Name:
N-cyclopropyl-5-[1-(4-fluorophenyl)pyrazolo[3,4-b]pyridin-4-yl]pyrimidin-4-Show More⌵

Mol. Formula:
C19H15FN6

M.W.:
346.37

Type:
---

AlogP:
3.59

Polar Surface Area:
68.52

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5275088

Name:
1-(3-fluoro-2-methoxy-phenyl)-4-(4-methyl-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C19H15FN4O

M.W.:
334.35

Type:
---

AlogP:
3.94

Polar Surface Area:
52.83

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5274940

Name:
1-(2,4-difluorophenyl)-4-(4-methyl-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C18H12F2N4

M.W.:
322.32

Type:
---

AlogP:
4.07

Polar Surface Area:
43.60

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5286511

Name:
1-(4-fluorophenyl)-4-(4-methyl-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C18H13FN4

M.W.:
304.33

Type:
---

AlogP:
3.93

Polar Surface Area:
43.60

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5286288

Name:
1-(4-fluorophenyl)-4-(4-methoxy-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C18H13FN4O

M.W.:
320.33

Type:
---

AlogP:
3.63

Polar Surface Area:
52.83

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5286147

Name:
5-[1-(2,4,6-trifluorophenyl)pyrazolo[3,4-b]pyridin-4-yl]pyrimidin-4-amine

Mol. Formula:
C16H9F3N6

M.W.:
342.28

Type:
---

AlogP:
2.88

Polar Surface Area:
82.51

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5286021

Name:
4-methyl-3-(3-phenylbenzothiophen-7-yl)pyridine

Mol. Formula:
C20H15NS

M.W.:
301.41

Type:
---

AlogP:
5.94

Polar Surface Area:
12.89

HBA:
2

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5285321

Name:
7-(4-methyl-3-pyridyl)-3-phenyl-thieno[3,2-b]pyridine

Mol. Formula:
C19H14N2S

M.W.:
302.40

Type:
---

AlogP:
5.33

Polar Surface Area:
25.78

HBA:
3

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5284859

Name:
1-(2-chloro-4-fluoro-phenyl)-4-(4-methyl-3-pyridyl)pyrazolo[3,4-b]pyridine

Mol. Formula:
C18H12ClFN4

M.W.:
338.77

Type:
---

AlogP:
4.58

Polar Surface Area:
43.60

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.54

DETAILS