Compounds

ALA5272676

Name:
3-{5-[1-(2-Fluoro-ethyl)-piperidin-4-yl]-[1,3,4]oxadiazol-2-yl}-1-isopropylShow More⌵

Mol. Formula:
C19H24FN5O

M.W.:
357.43

Type:
---

AlogP:
3.82

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5272596

Name:
1-Isopropyl-3-{5-[1-(2-methoxy-ethyl)-piperidin-4-yl]-[1,3,4]oxadiazol-2-ylShow More⌵

Mol. Formula:
C22H29N5O6

M.W.:
459.50

Type:
---

AlogP:
3.49

Polar Surface Area:
69.21

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA5271303

Name:
1-Isopropyl-1H-indazole-3-carboxylic acid [1-(tetrahydro-pyran-4-ylmethyl)-Show More⌵

Mol. Formula:
C23H34N4O2

M.W.:
398.55

Type:
---

AlogP:
3.49

Polar Surface Area:
59.39

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5271080

Name:
1-Isopropyl-1H-indazole-3-carboxylic acid [3-(tetrahydro-pyran-4-yl)-3-azabShow More⌵

Mol. Formula:
C24H32N4O6

M.W.:
472.54

Type:
---

AlogP:
2.70

Polar Surface Area:
59.39

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.86

DETAILS

ALA5270858

Name:
3-[5-(1-Cyclobutyl-piperidin-4-yl)-[1,3,4]oxadiazol-2-yl]-1-isopropyl-1H-inShow More⌵

Mol. Formula:
C23H29N5O5

M.W.:
455.52

Type:
---

AlogP:
4.40

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5270492

Name:
1-Isopropyl-1H-indazole-3-carboxylic acid[1-(2-hydroxy-ethyl)-piperidin-4-yShow More⌵

Mol. Formula:
C20H28N4O6

M.W.:
420.47

Type:
---

AlogP:
1.80

Polar Surface Area:
70.39

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.88

DETAILS

ALA5270411

Name:
1-Isopropyl-1H-indazole-3-carboxylic acid [3-(2-fluoro-ethyl)-3-azabicyclo[Show More⌵

Mol. Formula:
C18H23FN4O

M.W.:
330.41

Type:
---

AlogP:
2.25

Polar Surface Area:
50.16

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA5270036

Name:
1-Isopropyl-3-(5-piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-1H-indazole oxalate

Mol. Formula:
C19H23N5O5

M.W.:
401.42

Type:
---

AlogP:
3.13

Polar Surface Area:
68.77

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA5269243

Name:
1-Isopropyl-3-{5-[1-(3-methylsulfanyl-propyl)-piperidin-4-yl]-[1,3,4]oxadiaShow More⌵

Mol. Formula:
C23H31N5O5S

M.W.:
489.60

Type:
---

AlogP:
4.60

Polar Surface Area:
59.98

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5268956

Name:
4-{4-[5-(1-Isopropyl-1H-indazol-3-yl)-[1,3,4]oxadiazol-2-yl]-piperidin-1-ylShow More⌵

Mol. Formula:
C24H33N5O6

M.W.:
487.56

Type:
---

AlogP:
4.01

Polar Surface Area:
80.21

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA5268064

Name:
3-{4-[5-(1-Isopropyl-1H-indazol-3-yl)-[1,3,4]oxadiazol-2-yl]-piperidin-1-ylShow More⌵

Mol. Formula:
C22H29N5O6

M.W.:
459.50

Type:
---

AlogP:
3.23

Polar Surface Area:
80.21

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA5267721

Name:
1-Isopropyl-3-{5-[8-(3-methoxy-propyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-[1,3,4Show More⌵

Mol. Formula:
C25H33N5O6

M.W.:
499.57

Type:
---

AlogP:
4.41

Polar Surface Area:
69.21

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5282158

Name:
2-(7-(4-((1-(phenylsulfonyl)-1H-indol-4-yl)methyl)piperazin-1-yl)heptyl)-4,Show More⌵

Mol. Formula:
C36H43N5O3S2

M.W.:
657.91

Type:
---

AlogP:
6.21

Polar Surface Area:
78.22

HBA:
8

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.17

DETAILS

ALA5282103

Name:
3-[5-(1-Cyclopropyl-piperidin-4-ylmethyl)-[1,3,4]oxadiazol-2-yl]-1-isopropyShow More⌵

Mol. Formula:
C23H29N5O5

M.W.:
455.52

Type:
---

AlogP:
4.08

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA5281997

Name:
1-Isopropyl-3-[3-(1-isopropyl-piperidin-4-yl)-[1,2,4]oxadiazol-5-yl]-1H-indShow More⌵

Mol. Formula:
C20H27N5O

M.W.:
353.47

Type:
---

AlogP:
4.26

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5281673

Name:
2-(7-(4-((1-(phenylsulfonyl)-1H-indol-4-yl)methyl)piperazin-1-yl)heptyl)-2,Show More⌵

Mol. Formula:
C35H41N5O3S2

M.W.:
643.88

Type:
---

AlogP:
5.82

Polar Surface Area:
78.22

HBA:
8

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.18

DETAILS

ALA5281474

Name:
4-(6-{[(1-Isopropyl-1H-indazole-3-carbonyl)-amino]-methyl}-3-azabicyclo[3.1Show More⌵

Mol. Formula:
C26H35N5O7

M.W.:
529.59

Type:
---

AlogP:
2.76

Polar Surface Area:
79.70

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5281078

Name:
1-Isopropyl-1H-indazole-3-carboxylic acid [8-(tetrahydro-pyran-4-ylmethyl)-Show More⌵

Mol. Formula:
C28H40N4O8

M.W.:
560.65

Type:
---

AlogP:
3.77

Polar Surface Area:
59.39

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5281000

Name:
1-Isopropyl-1H-indazole-3-carboxylic acid [1-(3-methoxy-2,2-dimethyl-propylShow More⌵

Mol. Formula:
C26H40N4O8

M.W.:
536.63

Type:
---

AlogP:
3.48

Polar Surface Area:
59.39

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5280851

Name:
1-isopropyl-1H-indazole-3-carboxylic Acid[1-(3-hydroxy-propyl)-piperidin-4-Show More⌵

Mol. Formula:
C23H34N4O8

M.W.:
494.55

Type:
---

AlogP:
2.19

Polar Surface Area:
70.39

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.84

DETAILS