Compounds

ALA5272355

Name:
5-chloro-N-(cyclopropylsulfonyl)-4-(2-(1-(3,5-dichlorobenzyl)-4-fluoropiperShow More⌵

Mol. Formula:
C24H25Cl3F2N2O4S

M.W.:
581.90

Type:
---

AlogP:
5.78

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5272252

Name:
4-(2-(8-benzyl-8-azaspiro[4.5]decan-2-yl)ethoxy)-5-chloro-N-(cyclopropylsulShow More⌵

Mol. Formula:
C28H34ClFN2O4S

M.W.:
549.11

Type:
---

AlogP:
5.55

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5272143

Name:
5-Cyclopropyl-N-(cyclopropylsulfonyl)-4-((1-ethyl-4,4-difluorocyclohexyl)meShow More⌵

Mol. Formula:
C22H28F3NO4S

M.W.:
459.53

Type:
---

AlogP:
4.91

Polar Surface Area:
72.47

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5272127

Name:
4-(2-(8-benzyl-8-axaspiro[4.5]decan-2-yl)ethoxy)-N-(cyclo-propylsulfonyl)-2Show More⌵

Mol. Formula:
C29H37FN2O4S

M.W.:
528.69

Type:
---

AlogP:
5.21

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5271473

Name:
4-((8-benzyl-8-azaspiro[4.5]decan-2-yl)methoxy)-N-(cyclopropylsulfonyl)benzShow More⌵

Mol. Formula:
C27H34N2O4S

M.W.:
482.65

Type:
---

AlogP:
4.37

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5271438

Name:
4-(2-(8-benzyl-8-azaspiro[4.5]decan-2-yl)ethoxy)-N-(cyclopropylsulfonyl)-2,Show More⌵

Mol. Formula:
C28H34F2N2O4S

M.W.:
532.65

Type:
---

AlogP:
5.04

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA5270997

Name:
5-Chloro-2-fluoro-N-(methylsulfonyl)-4-((tetrahydro-2H-pyran-4-yl)methoxy)bShow More⌵

Mol. Formula:
C14H17ClFNO5S

M.W.:
365.81

Type:
---

AlogP:
1.97

Polar Surface Area:
81.70

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.86

DETAILS

ALA5270410

Name:
4-((8-azaspiro[4.5]decan-2-yl)methoxy)-N-(cyclopropylsulfonyl)benzamide

Mol. Formula:
C20H28N2O4S

M.W.:
392.52

Type:
---

AlogP:
2.46

Polar Surface Area:
84.50

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5268960

Name:
5-chloro-N-(cyclopropylsulfonyl)-4-(2-(8-ethyl-8-azaspiro[4.5]decan-2-yl)etShow More⌵

Mol. Formula:
C23H32ClFN2O4S

M.W.:
487.04

Type:
---

AlogP:
4.37

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5281672

Name:
5-chloro-N-(cyclopropylsulfonyl)-2-fluoro-4-(2-(8-(furan-2-ylmethyl)8-azaspShow More⌵

Mol. Formula:
C26H32ClFN2O5S

M.W.:
539.07

Type:
---

AlogP:
5.15

Polar Surface Area:
88.85

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA5280392

Name:
4-((3-azaspiro[5.5]undecan-9-yl)oxy)-N-(cyclopropylsulfonyl)benzamide

Mol. Formula:
C20H28N2O4S

M.W.:
392.52

Type:
---

AlogP:
2.60

Polar Surface Area:
84.50

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA5279943

Name:
4-(Adamantan-1-ylmethoxy)-2-fluoro-5-isopropyl-N-(methylsulfonyl)benzamide

Mol. Formula:
C22H30FNO4S

M.W.:
423.55

Type:
---

AlogP:
4.23

Polar Surface Area:
72.47

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5278784

Name:
5-chloro-N-(cyclopropylsulfonyl)-2-fluoro-4-(2-(8-(4-methoxybenzyl)8-azaspiShow More⌵

Mol. Formula:
C29H36ClFN2O5S

M.W.:
579.13

Type:
---

AlogP:
5.56

Polar Surface Area:
84.94

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5278479

Name:
4-((7-benzyl-7-azaspiro[3.5]nonan-2-yl)oxy)-N-(cyclopropylsulfonyl)benzamidShow More⌵

Mol. Formula:
C25H30N2O4S

M.W.:
454.59

Type:
---

AlogP:
3.73

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5278144

Name:
5-chloro-N-(cyclopropylsulfonyl)-4-(2-(8-(4-ethylbenzyl)-8-azaspiro[4.5]decShow More⌵

Mol. Formula:
C30H38ClFN2O4S

M.W.:
577.16

Type:
---

AlogP:
6.11

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.37

DETAILS

ALA5274914

Name:
5-chloro-4-(2-(8-(4-chlorobenzyl)-8-azaspiro[4.5]decan-2-yl)ethoxy)N-(cycloShow More⌵

Mol. Formula:
C28H33Cl2FN2O4S

M.W.:
583.55

Type:
---

AlogP:
6.21

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA5274422

Name:
N-(cyclopropylsulfonyl)-4-((3-ethyl-3-azaspiro[5.5]undecan-9-yl)oxy)benzamiShow More⌵

Mol. Formula:
C22H32N2O4S

M.W.:
420.58

Type:
---

AlogP:
3.33

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5274048

Name:
N-cyclopropylsulfonyl-4-[(8-ethyl-8-azaspiro[4.5]decan-3-yl)oxy]benzamide

Mol. Formula:
C21H30N2O4S

M.W.:
406.55

Type:
---

AlogP:
2.94

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5273963

Name:
5-chloro-N-(cyclopropylsulfonyl)-2-fluoro-4-(2-(8-(naphthalen-1-ylmethyl)-8Show More⌵

Mol. Formula:
C32H36ClFN2O4S

M.W.:
599.17

Type:
---

AlogP:
6.71

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA5287117

Name:
4-(2-(8-azaspiro[4.5]decan-2-yl)ethoxy)-N-(cyclopropylsulfonyl)benzamide

Mol. Formula:
C21H30N2O4S

M.W.:
406.55

Type:
---

AlogP:
2.85

Polar Surface Area:
84.50

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.73

DETAILS