Compounds

Type:
Unknown

AlogP:
2.64

Polar Surface Area:
64.35

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.87

DETAILS

ALA4648908

Name:
(2S,5R)-5-(5-(2-fluorobenzyloxy)pyridin-2-yl)pyrrolidine-2-carboxamide

Mol. Formula:
C17H18FN3O2

M.W.:
315.35

Type:
Unknown

AlogP:
2.08

Polar Surface Area:
77.24

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA4648552

Name:
(2S,5R)-5-(4-(3-fluorophenoxy)phenyl)pyrrolidine-2-carboxamide

Mol. Formula:
C17H17FN2O2

M.W.:
300.33

Type:
Unknown

AlogP:
2.90

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA4647983

Name:
(2R,5S)-5-(4-(2-fluorobenzyloxy)phenyl)pyrrolidine-2-carboxamide

Mol. Formula:
C18H19FN2O2

M.W.:
314.36

Type:
Unknown

AlogP:
2.68

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA4647249

Name:
rel-(2R,6S)-6-(4-(3-fluorobenzyloxy)phenyl)piperidine-2-carboxamide

Mol. Formula:
C19H21FN2O2

M.W.:
328.39

Type:
Unknown

AlogP:
3.07

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA4646990

Name:
(2S,5R)-5-(3-phenoxyphenyl)pyrrolidine-2-carboxamide

Mol. Formula:
C17H18N2O2

M.W.:
282.34

Type:
Unknown

AlogP:
2.76

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA4646446

Name:
(2S,5R)-5-(4-(2-fluorobenzyloxy)-3-methoxyphenyl)pyrrolidine-2-carboxamide

Mol. Formula:
C19H21FN2O3

M.W.:
344.39

Type:
Unknown

AlogP:
2.69

Polar Surface Area:
73.58

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.84

DETAILS

ALA4646035

Name:
2-(8-(2-fluorobenzyloxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propanamShow More⌵

Mol. Formula:
C19H21FN2O3

M.W.:
344.39

Type:
Unknown

AlogP:
2.47

Polar Surface Area:
64.79

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA4645734

Name:
(2S,5R)-5-(4-(4-cyanobenzyloxy)phenyl)pyrrolidine-2-carboxamide

Mol. Formula:
C19H19N3O2

M.W.:
321.38

Type:
Unknown

AlogP:
2.42

Polar Surface Area:
88.14

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.88

DETAILS

ALA4645660

Name:
2-(5-(2-fluorobenzyloxy)isoindolin-2-yl)acetamide

Mol. Formula:
C17H17FN2O2

M.W.:
300.33

Type:
Unknown

AlogP:
2.21

Polar Surface Area:
55.56

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.92

DETAILS

ALA4644773

Name:
(2S,5R)-5-(4-(benzyloxy)phenyl)pyrrolidine-2-carboxamide

Mol. Formula:
C18H20N2O2

M.W.:
296.37

Type:
Unknown

AlogP:
2.54

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA4644347

Name:
(2S,5R)-5-(4-(3-fluorobenzyloxy)phenyl)pyrrolidine-2-carboxamide

Mol. Formula:
C18H19FN2O2

M.W.:
314.36

Type:
Unknown

AlogP:
2.68

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA4644276

Name:
(2R,5R)-5-(4-(2-fluorobenzyloxy)phenyl)pyrrolidine-2-carboxamide

Mol. Formula:
C18H19FN2O2

M.W.:
314.36

Type:
Unknown

AlogP:
2.68

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA4644021

Name:
(R)-8-(2-fluorobenzyloxy)-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine-3-carboShow More⌵

Mol. Formula:
C17H17FN2O2S

M.W.:
332.40

Type:
Unknown

AlogP:
2.45

Polar Surface Area:
64.35

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA4643538

Name:
2-(4-(2-fluorobenzyloxy)benzylamino)acetamide

Mol. Formula:
C16H17FN2O2

M.W.:
288.32

3 activity values

2 unique targets

Type:
Unknown

AlogP:
1.98

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA4643518

Name:
2-(5-(2-fluorobenzyloxy)-2,3-dihydro-1H-inden-1-ylamino)acetamide

Mol. Formula:
C18H19FN2O2

M.W.:
314.36

Type:
Unknown

AlogP:
2.47

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.86

DETAILS

ALA4643471

Name:
(2S)-2-(6-(2-fluorobenzyloxy)-1,2,3,4-tetrahydronaphthalen-1-ylamino)propanShow More⌵

Mol. Formula:
C20H23FN2O2

M.W.:
342.41

Type:
Unknown

AlogP:
3.25

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.85

DETAILS

ALA4643129

Name:
3-(4-(2-fluorobenzyloxy)benzylamino)pyrrolidin-2-one

Mol. Formula:
C18H19FN2O2

M.W.:
314.36

3 activity values

2 unique targets

Type:
Unknown

AlogP:
2.38

Polar Surface Area:
50.36

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.86

DETAILS

ALA4642930

Name:
(2S,5R)-5-(4-(4-fluorobenzyloxy)phenyl)pyrrolidine-2-carboxamide

Mol. Formula:
C18H19FN2O2

M.W.:
314.36

9 activity values

Type:
Unknown

AlogP:
2.68

Polar Surface Area:
64.35

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA4642598

Name:
4-(4-(2-fluorobenzyloxy)benzyl)piperazin-2-one

Mol. Formula:
C18H19FN2O2

M.W.:
314.36