Compounds

ALA4798938

Name:
4-(2-fluoro-6-(3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy)-4-methoxy-3-Show More⌵

Mol. Formula:
C23H15F8N3O6

M.W.:
581.37

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.44

Polar Surface Area:
122.00

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA4796719

Name:
2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)-5-(trifluoromethyl)Show More⌵

Mol. Formula:
C18H18F5N5O3S

M.W.:
479.43

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.02

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA4788313

Name:
2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)-6-(trifluoromethyl)Show More⌵

Mol. Formula:
C18H18F5N5O3S

M.W.:
479.43

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.02

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA4787299

Name:
4-(2-fluoro-6-(3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy)-3-methoxy-4-Show More⌵

Mol. Formula:
C23H15F8N3O6

M.W.:
581.37

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.44

Polar Surface Area:
122.00

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA4785523

Name:
4-(2-chloro-6-(2-methoxy-4-(trifluoromethoxy)phenoxy)-3-(trifluoromethyl)beShow More⌵

Mol. Formula:
C22H14ClF6N3O5

M.W.:
549.81

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.80

Polar Surface Area:
112.77

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4782190

Name:
4-(2-fluoro-4-methoxy-6-(2-methoxy-4-(trifluoromethoxy)phenoxy)-3-(trifluorShow More⌵

Mol. Formula:
C23H16F7N3O6

M.W.:
563.38

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.30

Polar Surface Area:
122.00

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4781110

Name:
6-(cyclopropylmethyl)-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yShow More⌵

Mol. Formula:
C21H25F2N5O3S

M.W.:
465.53

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.95

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4778738

Name:
2-(4,4-difluoroazepan-1-yl)-6-methyl-N-(2-sulfamoylpyridin-4-yl)nicotinamidShow More⌵

Mol. Formula:
C18H21F2N5O3S

M.W.:
425.46

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.31

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA4777784

Name:
5-chloro-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-yl)nicotinamidShow More⌵

Mol. Formula:
C17H18ClF2N5O3S

M.W.:
445.88

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.66

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA4777598

Name:
2-(4,4-difluoroazepan-1-yl)-6-methyl-N-(2-sulfamoylpyridin-4-yl)-5-(trifluoShow More⌵

Mol. Formula:
C19H20F5N5O3S

M.W.:
493.46

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.33

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA4764805

Name:
4-(6-(3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy)-2-methyl-3-(trifluoroShow More⌵

Mol. Formula:
C23H16F7N3O5

M.W.:
547.38

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.60

Polar Surface Area:
112.77

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.37

DETAILS

ALA4764433

Name:
2-(4,4-difluoroazepan-1-yl)-5,6-dimethyl-N-(2-sulfamoylpyridin-4-yl)nicotinShow More⌵

Mol. Formula:
C19H23F2N5O3S

M.W.:
439.49

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.62

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA4763419

Name:
4-(3-chloro-2-fluoro-6-(3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy)benzShow More⌵

Mol. Formula:
C21H13ClF5N3O5

M.W.:
517.79

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.06

Polar Surface Area:
112.77

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4763229

Name:
5-(cyclopropylethynyl)-2-(4,4-difluoropiperidin-1-yl)-6-methyl-N-(2-sulfamoShow More⌵

Mol. Formula:
C22H23F2N5O3S

M.W.:
475.52

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.68

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4761578

Name:
4-(2-bromo-6-(2-methoxy-4-(trifluoromethoxy)phenoxy)-3-(trifluoromethyl)benShow More⌵

Mol. Formula:
C22H14BrF6N3O5

M.W.:
594.26

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.91

Polar Surface Area:
112.77

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA4760292

Name:
5-chloro-2-(4,4-difluoroazepan-1-yl)-6-methyl-N-(2-sulfamoylpyridin-4-yl)niShow More⌵

Mol. Formula:
C18H20ClF2N5O3S

M.W.:
459.91

1 activity values

1 unique targets

Type:
Unknown

AlogP:
2.96

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA4759995

Name:
5-chloro-6-cyclopropyl-2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridin-4-Show More⌵

Mol. Formula:
C20H22ClF2N5O3S

M.W.:
485.94

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.53

Polar Surface Area:
118.28

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA4759624

Name:
4-(6-(2-methoxy-4-(trifluoromethoxy)phenoxy)-2-methyl-3-(trifluoromethyl)beShow More⌵

Mol. Formula:
C23H17F6N3O5

M.W.:
529.39

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.46

Polar Surface Area:
112.77

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4756380

Name:
4-(3-chloro-2-fluoro-6-(3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy)-4-mShow More⌵

Mol. Formula:
C22H15ClF5N3O6

M.W.:
547.82

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.07

Polar Surface Area:
122.00

HBA:
7

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA4753280

Name:
4-(2-fluoro-6-(3-fluoro-2-methoxy-4-(trifluoromethoxy)phenoxy)-3-methyl-4-(Show More⌵

Mol. Formula:
C23H15F8N3O5

M.W.:
565.37

1 activity values

1 unique targets

Type:
Unknown

AlogP:
5.74

Polar Surface Area:
112.77

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.35

DETAILS