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  1. ALA5209108

    Name:
    tert-butyl 4-(3-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazShow More

    Mol. Formula:
    C31H38N6O5

    M.W.:
    574.68

    Type:
    ---

    AlogP:
    4.72

    Polar Surface Area:
    119.72

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.34

    DETAILS
  2. ALA5209089

    Name:
    3-(dimethylamino)-N-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imShow More

    Mol. Formula:
    C26H30N6O3

    M.W.:
    474.57

    Type:
    ---

    AlogP:
    2.98

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS
  3. ALA5207887

    Name:
    1-(1-(dimethylamino)propan-2-yl)-3-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,Show More

    Mol. Formula:
    C26H32N6O3

    M.W.:
    476.58

    Type:
    ---

    AlogP:
    3.27

    Polar Surface Area:
    93.42

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  4. ALA5207735

    Name:
    N-(2,3-difluoro-4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazoShow More

    Mol. Formula:
    C26H28F2N6O3

    M.W.:
    510.55

    Type:
    ---

    AlogP:
    3.26

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  5. ALA5206686

    Name:
    N-(3-fluoro-4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5Show More

    Mol. Formula:
    C27H31FN6O3

    M.W.:
    506.58

    Type:
    ---

    AlogP:
    3.43

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  6. ALA5206081

    Name:
    4-ethyl-N-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-Show More

    Mol. Formula:
    C27H32N6O3

    M.W.:
    488.59

    Type:
    ---

    AlogP:
    3.37

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  7. ALA5204408

    Name:
    1-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolShow More

    Mol. Formula:
    C26H30N6O3

    M.W.:
    474.57

    Type:
    ---

    AlogP:
    3.03

    Polar Surface Area:
    93.42

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  8. ALA5204162

    Name:
    1-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolShow More

    Mol. Formula:
    C27H32N6O3

    M.W.:
    488.59

    Type:
    ---

    AlogP:
    3.42

    Polar Surface Area:
    93.42

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  9. ALA5203201

    Name:
    1-(2-(dimethylamino)ethyl)-3-(5-(3-methyl-2-oxo-1-(tetrahydro-2H-pyran-4-ylShow More

    Mol. Formula:
    C26H31N7O3

    M.W.:
    489.58

    Type:
    ---

    AlogP:
    2.98

    Polar Surface Area:
    106.31

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  10. ALA5201821

    Name:
    4-methyl-N-(5-(3-methyl-2-oxo-1-(tetrahydro-2H-pyran-4-yl)-2,3-dihydro-1H-iShow More

    Mol. Formula:
    C27H31N7O3

    M.W.:
    501.59

    Type:
    ---

    AlogP:
    3.08

    Polar Surface Area:
    97.52

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS
  11. ALA5200256

    Name:
    N-(2-fluoro-4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5Show More

    Mol. Formula:
    C26H29FN6O3

    M.W.:
    492.56

    Type:
    ---

    AlogP:
    3.12

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS
  12. ALA5200163

    Name:
    N-(3-fluoro-4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5Show More

    Mol. Formula:
    C26H29FN6O3

    M.W.:
    492.56

    Type:
    ---

    AlogP:
    3.12

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS
  13. ALA5200053

    Name:
    N-(3-chloro-2-fluoro-4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imShow More

    Mol. Formula:
    C26H28ClFN6O3

    M.W.:
    527.00

    Type:
    ---

    AlogP:
    3.77

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  14. ALA5199423

    Name:
    1-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolShow More

    Mol. Formula:
    C26H30N6O3

    M.W.:
    474.57

    Type:
    ---

    AlogP:
    3.08

    Polar Surface Area:
    102.21

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.40

    DETAILS
  15. ALA5198342

    Name:
    1-(2-(3,3-difluoroazetidin-1-yl)ethyl)-3-(4-(1-(2-methoxyethyl)-3-methyl-2-Show More

    Mol. Formula:
    C26H28F2N6O3

    M.W.:
    510.55

    Type:
    ---

    AlogP:
    3.27

    Polar Surface Area:
    93.42

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.38

    DETAILS
  16. ALA5195925

    Name:
    (1S,4S)-N-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-Show More

    Mol. Formula:
    C27H30N6O3

    M.W.:
    486.58

    Type:
    ---

    AlogP:
    3.12

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.47

    DETAILS
  17. ALA5195854

    Name:
    tert-butyl 1-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4Show More

    Mol. Formula:
    C31H38N6O5

    M.W.:
    574.68

    Type:
    ---

    AlogP:
    4.72

    Polar Surface Area:
    119.72

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.34

    DETAILS
  18. ALA5193567

    Name:
    N-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolShow More

    Mol. Formula:
    C26H30N6O3

    M.W.:
    474.57

    Type:
    ---

    AlogP:
    2.98

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.48

    DETAILS
  19. ALA5191923

    Name:
    1-(2-(3-Fluoroazetidin-1-yl)ethyl)-3-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-Show More

    Mol. Formula:
    C26H29FN6O3

    M.W.:
    492.56

    Type:
    ---

    AlogP:
    2.98

    Polar Surface Area:
    93.42

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.39

    DETAILS
  20. ALA5191914

    Name:
    1-(2-(dimethylamino)ethyl)-3-(4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihyShow More

    Mol. Formula:
    C26H32N6O3

    M.W.:
    476.58

    Type:
    ---

    AlogP:
    3.23

    Polar Surface Area:
    84.63

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
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