Compounds

Type:
Unknown

AlogP:
2.74

Polar Surface Area:
78.85

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA4878813

Name:
(R)-3-amino-4-(5-(4-(4-fluorophenoxy)phenyl)-2H-tetrazol-2-yl)butanoic acid

Mol. Formula:
C17H16FN5O3

M.W.:
357.35

Type:
Unknown

AlogP:
2.07

Polar Surface Area:
116.15

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4877514

Name:
3-(5-(4-(4-Chlorophenoxy)phenyl)-2H-tetrazol-2-yl)propanoic acid

Mol. Formula:
C16H13ClN4O3

M.W.:
344.76

Type:
Unknown

AlogP:
3.26

Polar Surface Area:
90.13

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA4875741

Name:
(S)-2-Amino-3-(5-(4-(4-chlorophenoxy)phenyl)-2H-tetrazol-2-yl)propanoic aciShow More⌵

Mol. Formula:
C16H14ClN5O3

M.W.:
359.77

Type:
Unknown

AlogP:
2.20

Polar Surface Area:
116.15

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4875329

Name:
2-(5-(4-Methoxyphenyl)-2H-tetrazol-2-yl)ethan-1-amine

Mol. Formula:
C10H13N5O

M.W.:
219.25

1 unique targets

Type:
Unknown

AlogP:
0.31

Polar Surface Area:
78.85

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA4874348

Name:
(R)-3-Amino-4-(5-(4-((benzyloxy)methyl)phenyl)-2H-tetrazol-2-yl)butanoic acShow More⌵

Mol. Formula:
C19H21N5O3

M.W.:
367.41

Type:
Unknown

AlogP:
1.86

Polar Surface Area:
116.15

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4874303

Name:
(R)-3-Amino-4-(5-(4-((5-methoxypyrimidin-2-yl)oxy)phenyl)-2H-tetrazol-2-yl)Show More⌵

Mol. Formula:
C16H17N7O4

M.W.:
371.36

Type:
Unknown

AlogP:
0.73

Polar Surface Area:
151.16

HBA:
10

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4871711

Name:
(R)-3-Amino-4-(5-(4-((5-chloro-3-fluoropyridin-2-yl)oxy)phenyl)-2H-tetrazolShow More⌵

Mol. Formula:
C16H14ClFN6O3

M.W.:
392.78

Type:
Unknown

AlogP:
2.12

Polar Surface Area:
129.04

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA4871560

Name:
(R)-3-Amino-4-(5-(4-((5-chloropyridin-2-yl)oxy)phenyl)-2H-tetrazol-2-yl)butShow More⌵

Mol. Formula:
C16H15ClN6O3

M.W.:
374.79

Type:
Unknown

AlogP:
1.98

Polar Surface Area:
129.04

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.64

DETAILS

ALA4870397

Name:
4-(5-(4-(4-Chlorophenoxy)phenyl)-2H-tetrazol-2-yl)butanoic acid

Mol. Formula:
C17H15ClN4O3

M.W.:
358.79

Type:
Unknown

AlogP:
3.65

Polar Surface Area:
90.13

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4870263

Name:
(S)-3-amino-4-(5-(4-(((R)-1-phenylpropan-2-yl)oxy)phenyl)-2H-tetrazol-2-yl)Show More⌵

Mol. Formula:
C20H23N5O3

M.W.:
381.44

Type:
Unknown

AlogP:
2.15

Polar Surface Area:
116.15

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4869586

Name:
3-(5-(4-(4-Chlorophenoxy)phenyl)-2H-tetrazol-2-yl)propan-1-amine

Mol. Formula:
C16H16ClN5O

M.W.:
329.79

Type:
Unknown

AlogP:
3.13

Polar Surface Area:
78.85

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA4869350

Name:
(S)-3-Amino-4-(5-(4-((benzyloxy)methyl)phenyl)-2H-tetrazol-2-yl)butanoic acShow More⌵

Mol. Formula:
C19H21N5O3

M.W.:
367.41

Type:
Unknown

AlogP:
1.86

Polar Surface Area:
116.15

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4866709

Name:
(R)-3-Amino-4-(5-(4-phenethoxyphenyl)-2H-tetrazol-2-yl)butanoic acid

Mol. Formula:
C19H21N5O3

M.W.:
367.41

Type:
Unknown

AlogP:
1.76

Polar Surface Area:
116.15

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4861996

Name:
(R)-2-(5-(4-(4-Chlorophenoxy)phenyl)-2H-tetrazol-2-yl)propan-1-amine

Mol. Formula:
C16H16ClN5O

M.W.:
329.79

Type:
Unknown

AlogP:
3.31

Polar Surface Area:
78.85

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA4859847

Name:
(S)-3-Amino-4-(5-(4-(4-chlorophenoxy)phenyl)-2H-tetrazol-2-yl)butanoic acid

Mol. Formula:
C17H16ClN5O3

M.W.:
373.80

10 activity values

9 unique targets

Type:
Unknown

AlogP:
2.59

Polar Surface Area:
116.15

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA4858542

Name:
(R)-3-Amino-4-(5-(4-(4-chlorophenoxy)phenyl)-2H-tetrazol-2-yl)butanoic acid

Mol. Formula:
C17H16ClN5O3

M.W.:
373.80

10 activity values

9 unique targets

Type:
Unknown

AlogP:
2.59

Polar Surface Area:
116.15

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA4857223

Name:
(R)-3-Amino-4-(5-(4-(benzo[d]thiazol-2-yloxy)phenyl)-2H-tetrazol-2-yl)butanShow More⌵

Mol. Formula:
C18H16N6O3S

M.W.:
396.43

Type:
Unknown

AlogP:
2.54

Polar Surface Area:
129.04

HBA:
9

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4855474

Name:
(R)-1-(5-(4-(4-Chlorophenoxy)phenyl)-2H-tetrazol-2-yl)propan-2-amine

Mol. Formula:
C16H16ClN5O

M.W.:
329.79

Type:
Unknown

AlogP:
3.13

Polar Surface Area:
78.85

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA4853421

Name:
(2-(5-(4-(4-Chlorophenoxy)phenyl)-2H-tetrazol-2-yl)ethyl)glycine

Mol. Formula:
C17H16ClN5O3

M.W.:
373.80