Compounds

Type:
Unknown

AlogP:
4.13

Polar Surface Area:
145.51

HBA:
4

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4872604

Name:
(S)-2-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-4-methylpenShow More⌵

Mol. Formula:
C35H43N4O6P

M.W.:
646.73

8 activity values

Type:
Unknown

AlogP:
5.50

Polar Surface Area:
163.61

HBA:
5

HBD:
5

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.10

DETAILS

ALA4863168

Name:
(R)-2-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-4-methylpenShow More⌵

Mol. Formula:
C27H37N4O4P

M.W.:
512.59

7 activity values

Type:
Unknown

AlogP:
3.53

Polar Surface Area:
151.30

HBA:
4

HBD:
5

#RO5 Violations:
1

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4854733

Name:
(S)-2-((S)-3-(1H-indol-3-yl)-1-methoxy-1-oxopropan-2-ylcarbamoyl)-4-methylpShow More⌵

Mol. Formula:
C28H38N3O5P

M.W.:
527.60

7 activity values

Type:
Unknown

AlogP:
4.22

Polar Surface Area:
134.51

HBA:
5

HBD:
4

#RO5 Violations:
1

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA4853049

Name:
(S)-2-(2-(1H-indol-3-yl)ethylcarbamoyl)-4-methylpentyl((R)-1-amino-3-phenylShow More⌵

Mol. Formula:
C26H36N3O3P

M.W.:
469.57

8 activity values

Type:
Unknown

AlogP:
4.68

Polar Surface Area:
108.21

HBA:
3

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4593147

Name:
N-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethyl)Show More⌵

Mol. Formula:
C23H16F3N3O4

M.W.:
455.39

Type:
Unknown

AlogP:
3.24

Polar Surface Area:
107.53

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA4590563

Name:
N-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethyl)Show More⌵

Mol. Formula:
C22H17F3N4O4

M.W.:
458.40

Type:
Unknown

AlogP:
2.84

Polar Surface Area:
137.04

HBA:
5

HBD:
5

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.10

DETAILS

ALA4589359

Name:
N-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethyl)Show More⌵

Mol. Formula:
C22H17F3N4O4

M.W.:
458.40

Type:
Unknown

AlogP:
2.84

Polar Surface Area:
137.04

HBA:
5

HBD:
5

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.10

DETAILS

ALA4586845

Name:
N-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethyl)Show More⌵

Mol. Formula:
C22H16F3N3O4

M.W.:
443.38

Type:
Unknown

AlogP:
2.85

Polar Surface Area:
121.52

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.27

DETAILS

ALA4586126

Name:
N1-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethylShow More⌵

Mol. Formula:
C25H22F3N3O4

M.W.:
485.46

Type:
Unknown

AlogP:
3.89

Polar Surface Area:
107.53

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.23

DETAILS

ALA4579696

Name:
N-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethyl)Show More⌵

Mol. Formula:
C23H19F3N2O5

M.W.:
460.41

Type:
Unknown

AlogP:
3.76

Polar Surface Area:
96.89

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.28

DETAILS

ALA4578880

Name:
4-Fluoro-3-hydroxy-N-(2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biShow More⌵

Mol. Formula:
C21H14F4N2O4

M.W.:
434.35

Type:
Unknown

AlogP:
3.59

Polar Surface Area:
98.66

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA4572202

Name:
2-(2-(3,4-Dimethoxyphenyl)acetamido)-N-hydroxy-2-(3',4',5'-trifluoro-[1,1'-Show More⌵

Mol. Formula:
C24H21F3N2O5

M.W.:
474.44

Type:
Unknown

AlogP:
3.69

Polar Surface Area:
96.89

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.26

DETAILS

ALA4571223

Name:
3-Fluoro-N-(2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-Show More⌵

Mol. Formula:
C21H14F4N2O3

M.W.:
418.35

Type:
Unknown

AlogP:
3.89

Polar Surface Area:
78.43

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA4566082

Name:
N1-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethylShow More⌵

Mol. Formula:
C24H20F3N3O4

M.W.:
471.44

Type:
Unknown

AlogP:
3.45

Polar Surface Area:
98.74

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4566015

Name:
N-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethyl)Show More⌵

Mol. Formula:
C21H14F3N5O3

M.W.:
441.37

Type:
Unknown

AlogP:
3.02

Polar Surface Area:
120.00

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4564908

Name:
N-Hydroxy-2-(2-phenylacetamido)-2-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)Show More⌵

Mol. Formula:
C22H17F3N2O3

M.W.:
414.38

Type:
Unknown

AlogP:
3.68

Polar Surface Area:
78.43

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA4564549

Name:
N-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethyl)Show More⌵

Mol. Formula:
C22H15F3N4O3

M.W.:
440.38

Type:
Unknown

AlogP:
3.62

Polar Surface Area:
107.11

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.22

DETAILS

ALA4562848

Name:
3-Hydroxy-N-(2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4Show More⌵

Mol. Formula:
C21H15F3N2O4

M.W.:
416.36

Type:
Unknown

AlogP:
3.45

Polar Surface Area:
98.66

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.29

DETAILS

ALA4540925

Name:
N-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethyl)Show More⌵

Mol. Formula:
C21H15F3N2O3

M.W.:
400.36