Compounds

ALA5272324

Name:
4-chloro-N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-3-(trifluShow More⌵

Mol. Formula:
C21H16ClF3N2O4S

M.W.:
484.88

Type:
---

AlogP:
5.35

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5272312

Name:
5-chloro-2-methoxy-N-(1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinolin-6Show More⌵

Mol. Formula:
C26H27ClN2O6S

M.W.:
531.03

Type:
---

AlogP:
5.07

Polar Surface Area:
94.17

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5272204

Name:
N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-N-((5,6,7,8-tetrahShow More⌵

Mol. Formula:
C34H34N2O6S2

M.W.:
630.79

Type:
---

AlogP:
6.21

Polar Surface Area:
104.97

HBA:
6

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5271610

Name:
5-chloro-2-methoxy-4-methyl-N-(1-(thiophene-2-carbonyl)-1,2,3,4-tetrahydroqShow More⌵

Mol. Formula:
C22H21ClN2O4S2

M.W.:
477.01

Type:
---

AlogP:
5.11

Polar Surface Area:
75.71

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5270525

Name:
N-(ethylsulfonyl)-N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)eShow More⌵

Mol. Formula:
C18H22N2O6S2

M.W.:
426.52

Type:
---

AlogP:
2.38

Polar Surface Area:
104.97

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5269834

Name:
N-(1-acetyl-1,2,3,4-tetrahydroquinolin-6-yl)-5-chloro-2-methoxy-4-methylbenShow More⌵

Mol. Formula:
C19H21ClN2O4S

M.W.:
408.91

Type:
---

AlogP:
3.76

Polar Surface Area:
75.71

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.84

DETAILS

ALA5269740

Name:
N-(1-(cyclopropanecarbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-2-methoxy-4,5-Show More⌵

Mol. Formula:
C22H26N2O4S

M.W.:
414.53

Type:
---

AlogP:
3.80

Polar Surface Area:
75.71

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.81

DETAILS

ALA5269614

Name:
N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-4-nitro-N-((4-nitrShow More⌵

Mol. Formula:
C26H20N4O10S2

M.W.:
612.60

Type:
---

AlogP:
4.27

Polar Surface Area:
191.25

HBA:
10

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.20

DETAILS

ALA5269021

Name:
5-chloro-2-methoxy-4-methyl-N-(1-(4-(trifluoromethyl)benzoyl)-1,2,3,4-tetraShow More⌵

Mol. Formula:
C25H22ClF3N2O4S

M.W.:
538.98

Type:
---

AlogP:
6.07

Polar Surface Area:
75.71

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5268681

Name:
2-chloro-N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-6-methoxyShow More⌵

Mol. Formula:
C21H19ClN2O5S

M.W.:
446.91

Type:
---

AlogP:
4.34

Polar Surface Area:
88.85

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5282626

Name:
5-chloro-N-(1-(cyclopropanecarbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-2-metShow More⌵

Mol. Formula:
C21H23ClN2O4S

M.W.:
434.95

Type:
---

AlogP:
4.15

Polar Surface Area:
75.71

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5282323

Name:
5-chloro-N-(1-(4-fluorobenzoyl)-1,2,3,4-tetrahydroquinolin-6-yl)-2-methoxy-Show More⌵

Mol. Formula:
C24H22ClFN2O4S

M.W.:
488.97

Type:
---

AlogP:
5.19

Polar Surface Area:
75.71

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5282262

Name:
N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-4-propylbenzenesulShow More⌵

Mol. Formula:
C24H26N2O4S

M.W.:
438.55

Type:
---

AlogP:
5.02

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA5282207

Name:
4-chloro-N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-3-nitrobeShow More⌵

Mol. Formula:
C20H16ClN3O6S

M.W.:
461.88

Type:
---

AlogP:
4.24

Polar Surface Area:
122.76

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5282196

Name:
N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-4-methyl-N-tosylbeShow More⌵

Mol. Formula:
C28H26N2O6S2

M.W.:
550.66

Type:
---

AlogP:
5.07

Polar Surface Area:
104.97

HBA:
6

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA5282144

Name:
N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-4-methoxy-N-((4-meShow More⌵

Mol. Formula:
C28H26N2O8S2

M.W.:
582.66

Type:
---

AlogP:
4.47

Polar Surface Area:
123.43

HBA:
8

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA5281564

Name:
N-(1-(2-naphthoyl)-1,2,3,4-tetrahydroquinolin-6-yl)-5-chloro-2-methoxy-4-meShow More⌵

Mol. Formula:
C28H25ClN2O4S

M.W.:
521.04

Type:
---

AlogP:
6.20

Polar Surface Area:
75.71

HBA:
4

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA5281555

Name:
N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroShow More⌵

Mol. Formula:
C24H24N2O4S

M.W.:
436.53

Type:
---

AlogP:
4.55

Polar Surface Area:
79.62

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5280766

Name:
5-(dimethylamino)-N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)nShow More⌵

Mol. Formula:
C26H25N3O4S

M.W.:
475.57

Type:
---

AlogP:
4.89

Polar Surface Area:
82.86

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5280434

Name:
N-(1-(furan-2-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)-N-(thiophen-2-ylsuShow More⌵

Mol. Formula:
C22H18N2O6S4

M.W.:
534.66

Type:
---

AlogP:
4.58

Polar Surface Area:
104.97

HBA:
8

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.36

DETAILS