Compounds

Type:
---

AlogP:
2.45

Polar Surface Area:
143.84

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA5196592

Name:
2-amino-1-(5-hydroxy-2-methylphenyl)-1H-pyrrolo[3,2-b]quinoline-3-carboxamiShow More⌵

Mol. Formula:
C19H16N4O2

M.W.:
332.36

Type:
---

AlogP:
2.87

Polar Surface Area:
107.16

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5196095

Name:
2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5-(2-methylpyrazol-3-yl)pyrrolo[2,Show More⌵

Mol. Formula:
C23H21N7O2

M.W.:
427.47

Type:
---

AlogP:
2.98

Polar Surface Area:
137.87

HBA:
8

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA5204618

Name:
2-amino-N-ethyl-1-(5-hydroxy-2-methylphenyl)-1H-pyrrolo[2,3-b]quinoxaline-3Show More⌵

Mol. Formula:
C20H19N5O2

M.W.:
361.41

Type:
---

AlogP:
2.92

Polar Surface Area:
106.06

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5203261

Name:
2-amino-1-(5-hydroxy-2-methylphenyl)-1H-pyrrolo[2,3-b]quinoline-3-carboxamiShow More⌵

Mol. Formula:
C19H16N4O2

M.W.:
332.36

3 activity values

Type:
---

AlogP:
2.87

Polar Surface Area:
107.16

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5202826

Name:
2-amino-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxaShow More⌵

Mol. Formula:
C19H17N5O2

M.W.:
347.38

4 activity values

3 unique targets

Type:
---

AlogP:
2.58

Polar Surface Area:
120.05

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA5202444

Name:
2-amino-1-(6-chloro-3-hydroxy-2-methylphenyl)pyrrolo[3,2-b]quinoxaline-3-caShow More⌵

Mol. Formula:
C18H14ClN5O2

M.W.:
367.80

3 activity values

Type:
---

AlogP:
2.92

Polar Surface Area:
120.05

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5199806

Name:
2-amino-5-cyano-1-(3-hydroxy-2,6-dimethylphenyl)-1H-pyrrolo[2,3-b]quinoxaliShow More⌵

Mol. Formula:
C20H16N6O2

M.W.:
372.39

Type:
---

AlogP:
2.45

Polar Surface Area:
143.84

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA5199564

Name:
2-amino-1-(1H-indazol-4-yl)pyrrolo[3,2-b]quinoxaline-3-carboxamide

Mol. Formula:
C18H13N7O

M.W.:
343.35

Type:
---

AlogP:
2.13

Polar Surface Area:
128.50

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5208905

Name:
2-Amino-1-(4-hydroxy-2-methylphenyhpyrrolo(3,2-b)-quinozaline-3-carboxamide

Mol. Formula:
C18H15N5O2

M.W.:
333.35

Type:
---

AlogP:
2.27

Polar Surface Area:
120.05

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5208886

Name:
2-amino-1-(1H-indol-4-yl)pyrrolo[3,2-b]quinoxaline-3-carboxamide

Mol. Formula:
C19H14N6O

M.W.:
342.36

Type:
---

AlogP:
2.74

Polar Surface Area:
115.61

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA5208771

Name:
2-amino-1-(3-methoxy-2,6-dimethylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxaShow More⌵

Mol. Formula:
C20H19N5O2

M.W.:
361.41

Type:
---

AlogP:
2.88

Polar Surface Area:
109.05

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5195417

Name:
2-amino-7-bromo-1-(3-hydroxy-2,6-dimethylphenyl)-1H-pyrrolo[2,3-b]quinoxaliShow More⌵

Mol. Formula:
C19H16BrN5O2

M.W.:
426.27

Type:
---

AlogP:
3.34

Polar Surface Area:
120.05

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5193896

Name:
2-Amino-1-(3-hydroxy-2-methylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide

Mol. Formula:
C18H15N5O2

M.W.:
333.35

3 activity values

Type:
---

AlogP:
2.27

Polar Surface Area:
120.05

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA5191665

Name:
2-amino-1-(2-chloro-3-hydroxy-6-methylphenyl)pyrrolo[3,2-b]quinoxaline-3-caShow More⌵

Mol. Formula:
C18H14ClN5O2

M.W.:
367.80

4 activity values

3 unique targets

Type:
---

AlogP:
2.92

Polar Surface Area:
120.05

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA5190822

Name:
2-amino-8-(cyclopenten-1-yl)-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[3,2-b]Show More⌵

Mol. Formula:
C24H23N5O2

M.W.:
413.48

Type:
---

AlogP:
4.14

Polar Surface Area:
120.05

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA5189665

Name:
2-amino-1-(3-chloro-2,6-dimethylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamShow More⌵

Mol. Formula:
C19H16ClN5O

M.W.:
365.82

Type:
---

AlogP:
3.53

Polar Surface Area:
99.82

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5187022

Name:
2-amino-6-cyano-1-(3-hydroxy-2,6-dimethylphenyl)-1H-pyrrolo[2,3-b]quinoxaliShow More⌵

Mol. Formula:
C20H16N6O2

M.W.:
372.39

Type:
---

AlogP:
2.45

Polar Surface Area:
143.84

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA5186220

Name:
2-amino-8-bromo-1-(3-hydroxy-2,6-dimethylphenyl)-pyrrolo[3,2-b]quinoxaline-Show More⌵

Mol. Formula:
C19H16BrN5O2

M.W.:
426.27

Type:
---

AlogP:
3.34

Polar Surface Area:
120.05

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA5185146

Name:
2-amino-6-bromo-1-(3-hydroxy-2,6-dimethylphenyl)-pyrrolo[3,2-b]quinoxaline-Show More⌵

Mol. Formula:
C19H16BrN5O2

M.W.:
426.27