Compounds

Type:
Unknown

AlogP:
4.37

Polar Surface Area:
57.53

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4798697

Name:
Rac-methyl 2-(2,4-dichlorophenyl)-2-[4-(methanesulfonamido)indol-1-yl]acetaShow More⌵

Mol. Formula:
C18H16Cl2N2O4S

M.W.:
427.31

3 activity values

Type:
Unknown

AlogP:
4.08

Polar Surface Area:
77.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA4796191

Name:
(2R)-N-tert-butyl-2-(4-chlorophenyl)-2-[4-(methanesulfonamido)indol-1-yl]buShow More⌵

Mol. Formula:
C23H28ClN3O3S

M.W.:
462.02

Type:
Unknown

AlogP:
4.73

Polar Surface Area:
80.20

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4794194

Name:
Rac-methyl 2-(4-chlorophenyl)-2-[4-(methanesulfonamido)indol-1-yl]butanoate

Mol. Formula:
C20H21ClN2O4S

M.W.:
420.92

Type:
Unknown

AlogP:
3.99

Polar Surface Area:
77.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4794041

Name:
Rac-methyl 2-[4-(methanesulfonamido)indol-1-yl]-2-(4-methoxyphenyl)acetate

Mol. Formula:
C19H20N2O5S

M.W.:
388.45

Type:
Unknown

AlogP:
2.78

Polar Surface Area:
86.63

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4792628

Name:
methyl (2R)-2-(4-chlorophenyl)-2-[4-(methanesulfonamido)indol-1-yl]butanoatShow More⌵

Mol. Formula:
C20H21ClN2O4S

M.W.:
420.92

2 activity values

Type:
Unknown

AlogP:
3.99

Polar Surface Area:
77.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA4792176

Name:
N-[1-[(1R)-1-(4-chlorophenyl)-1-(5-phenyl-1,2,4-oxadiazol-3-yl)propyl]indolShow More⌵

Mol. Formula:
C26H23ClN4O3S

M.W.:
507.02

Type:
Unknown

AlogP:
5.92

Polar Surface Area:
90.02

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.30

DETAILS

ALA4790021

Name:
Rac-methyl 2-(4-chlorophenyl)-2-[4-(methanesulfonamido)indol-1-yl]propanoatShow More⌵

Mol. Formula:
C19H19ClN2O4S

M.W.:
406.89

Type:
Unknown

AlogP:
3.60

Polar Surface Area:
77.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4780739

Name:
Rac-methyl 2-(4-fluorophenyl)-2-[4-(methanesulfonamido)indol-1-yl]acetate

Mol. Formula:
C18H17FN2O4S

M.W.:
376.41

Type:
Unknown

AlogP:
2.91

Polar Surface Area:
77.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA4777887

Name:
Rac-methyl 2-(2-chloro-4-fluorophenyl)-2-indol-1-yl-acetate

Mol. Formula:
C17H13ClFNO2

M.W.:
317.75

Type:
Unknown

AlogP:
4.20

Polar Surface Area:
31.23

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4777170

Name:
Rac-methyl 2-(4-chlorophenyl)-3-cyano-2-[4-(methanesulfonamido)indol-1-yl]pShow More⌵

Mol. Formula:
C20H18ClN3O4S

M.W.:
431.90

Type:
Unknown

AlogP:
3.50

Polar Surface Area:
101.19

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA4776613

Name:
(2R)-2-(4-chlorophenyl)-2-[4-(methanesulfonamido)indol-1-yl]-N-(2,2,2-triflShow More⌵

Mol. Formula:
C21H21ClF3N3O3S

M.W.:
487.93

2 activity values

Type:
Unknown

AlogP:
4.50

Polar Surface Area:
80.20

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA4764165

Name:
N-[1-[(1R)-1-(4-chlorophenyl)-1-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)propyl]Show More⌵

Mol. Formula:
C23H23ClN4O3S

M.W.:
470.98

Type:
Unknown

AlogP:
5.13

Polar Surface Area:
90.02

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4763926

Name:
Rac-methyl 2-(2-chloro-4-fluorophenyl)-2-[4-[(2,2,2-trifluoroacetyl)amino]iShow More⌵

Mol. Formula:
C19H13ClF4N2O3

M.W.:
428.77

Type:
Unknown

AlogP:
4.70

Polar Surface Area:
60.33

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4760159

Name:
Rac-methyl 2-(4-chlorophenyl)-2-[4-(methanesulfonamido)indol-1-yl]-3-methoxShow More⌵

Mol. Formula:
C20H21ClN2O5S

M.W.:
436.92

Type:
Unknown

AlogP:
3.23

Polar Surface Area:
86.63

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA4759836

Name:
Rac-methyl 2-(4-chlorophenyl)-3-cyclopropyl-2-[4-(methanesulfonamido)indol-Show More⌵

Mol. Formula:
C22H23ClN2O4S

M.W.:
446.96

Type:
Unknown

AlogP:
4.38

Polar Surface Area:
77.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA4759690

Name:
Rac-methyl 2-(2-chloro-4-fluorophenyl)-2-[4-(trifluoromethylsulfonylamino)iShow More⌵

Mol. Formula:
C18H13ClF4N2O4S

M.W.:
464.82

Type:
Unknown

AlogP:
4.46

Polar Surface Area:
77.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4756852

Name:
Rac-methyl 2-(2-chloro-4-fluorophenyl)-2-(4-fluoroindol-1-yl)acetate

Mol. Formula:
C17H12ClF2NO2

M.W.:
335.74

Type:
Unknown

AlogP:
4.34

Polar Surface Area:
31.23

HBA:
3

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA4755269

Name:
Rac-methyl 2-(4-chlorophenyl)-2-[4-(methanesulfonamido)indol-1-yl]-3-phenylShow More⌵

Mol. Formula:
C25H23ClN2O4S

M.W.:
482.99

Type:
Unknown

AlogP:
4.83

Polar Surface Area:
77.40

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA4754975

Name:
Rac-methyl 2-(2-chloro-4-fluorophenyl)-2-(4-chloroindol-1-yl)acetate

Mol. Formula:
C17H12Cl2FNO2

M.W.:
352.19

3 activity values