Type:
Small molecule

AlogP:
3.63

Polar Surface Area:
200.01

HBA:
11

HBD:
5

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.18

Type:
Small molecule

AlogP:
2.95

Polar Surface Area:
140.23

HBA:
7

HBD:
5

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.32

Type:
Small molecule

AlogP:
2.60

Polar Surface Area:
220.24

HBA:
12

HBD:
6

#RO5 Violations:
3

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.15

Type:
Small molecule

AlogP:
2.49

Polar Surface Area:
209.24

HBA:
12

HBD:
5

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.25

Type:
Small molecule

AlogP:
3.52

Polar Surface Area:
189.01

HBA:
11

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.30

Type:
Small molecule

AlogP:
3.37

Polar Surface Area:
189.01

HBA:
11

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.29

Type:
Small molecule

AlogP:
2.49

Polar Surface Area:
209.24

HBA:
12

HBD:
5

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.24

Type:
Small molecule

AlogP:
5.43

Polar Surface Area:
129.66

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.18

Type:
Small molecule

AlogP:
4.97

Polar Surface Area:
110.13

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.26

Type:
Small molecule

AlogP:
5.20

Polar Surface Area:
145.81

HBA:
5

HBD:
4

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.07

Type:
Small molecule

AlogP:
6.62

Polar Surface Area:
76.74

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.32

Type:
Small molecule

AlogP:
5.65

Polar Surface Area:
89.90

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.25

Type:
Small molecule

AlogP:
5.91

Polar Surface Area:
112.59

HBA:
5

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.23

Type:
Small molecule

AlogP:
5.91

Polar Surface Area:
112.59

HBA:
5

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
13

Passes Ro3:
N

QED Weighted:
0.23

Type:
Small molecule

AlogP:
6.23

Polar Surface Area:
29.46

HBA:
2

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.53

Type:
Small molecule

AlogP:
6.23

Polar Surface Area:
29.46

HBA:
2

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.53

Type:
Small molecule

AlogP:
7.00

Polar Surface Area:
29.46

HBA:
2

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.39

Type:
Small molecule

AlogP:
6.23

Polar Surface Area:
29.46

HBA:
2

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.53

Type:
Small molecule

AlogP:
6.23

Polar Surface Area:
29.46

HBA:
2

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.53

Type:
Small molecule

AlogP:
6.23

Polar Surface Area:
29.46

HBA:
2

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.49