Compounds

ALA5267323

Name:
1-(4-(1H-pyrrolo[2,3-b]pyridin-6-yl)piperazin-1-yl)-2-(3,4-dichlorophenyl)eShow More⌵

Mol. Formula:
C19H18Cl2N4O

M.W.:
389.29

Type:
---

AlogP:
3.76

Polar Surface Area:
52.23

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5266891

Name:
1-(4-(1,5-naphthyridin-2-yl)piperazin-1-yl)-2-(3,4-dichlorophenyl)ethanone

Mol. Formula:
C20H18Cl2N4O

M.W.:
401.30

Type:
---

AlogP:
3.83

Polar Surface Area:
49.33

HBA:
4

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5266693

Name:
N-(3,4-dichlorophenyl)-4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)pipShow More⌵

Mol. Formula:
C17H17Cl2N7O

M.W.:
406.28

Type:
---

AlogP:
3.09

Polar Surface Area:
78.66

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5266604

Name:
(2R)-N-[(3R)-7-chloro-1-methyl-8-(oxetan-3-yloxy)-2-oxo-5-phenyl-2,3-dihydrShow More⌵

Mol. Formula:
C31H34ClF3N4O5

M.W.:
635.08

Type:
---

AlogP:
4.74

Polar Surface Area:
100.54

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5266541

Name:
2-(3,4-dichlorophenyl)-1-(4-(7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-Show More⌵

Mol. Formula:
C17H18Cl2N6O

M.W.:
393.28

Type:
---

AlogP:
2.08

Polar Surface Area:
66.62

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5266173

Name:
2-(3,4-dichlorophenyl)-1-(4-(7-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)Show More⌵

Mol. Formula:
C18H18Cl2N6O

M.W.:
405.29

Type:
---

AlogP:
2.63

Polar Surface Area:
66.63

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5282565

Name:
2-(3,4-dichlorophenyl)-1-(4-(pyrazolo[1,5-a]pyrimidin-5-yl)piperazin-1-yl)eShow More⌵

Mol. Formula:
C18H17Cl2N5O

M.W.:
390.27

Type:
---

AlogP:
2.93

Polar Surface Area:
53.74

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5282149

Name:
1-(4-(2-benzyl-2H-pyrazolo[4,3-b]pyridin-5-yl)piperazin-1-yl)-2-(3,4-dichloShow More⌵

Mol. Formula:
C25H23Cl2N5O

M.W.:
480.40

Type:
---

AlogP:
4.68

Polar Surface Area:
54.26

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA5281839

Name:
2-(3,4-dichlorophenyl)-1-(4-(2-(morpholine-4-carbonyl)imidazo[1,2-b]pyridazShow More⌵

Mol. Formula:
C23H24Cl2N6O3

M.W.:
503.39

Type:
---

AlogP:
2.40

Polar Surface Area:
83.28

HBA:
7

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA5281640

Name:
2-(3,4-dichlorophenyl)-1-(4-(6-methoxypyridazin-3-yl)piperazin-1-yl)ethanonShow More⌵

Mol. Formula:
C17H18Cl2N4O2

M.W.:
381.26

Type:
---

AlogP:
2.68

Polar Surface Area:
58.56

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5281558

Name:
N-(5-(4-(2-(3,4-dichlorophenyl)acetyl)piperazin-1-yl)thiazolo[4,5-b]pyridinShow More⌵

Mol. Formula:
C24H20Cl2N6O2S

M.W.:
527.44

Type:
---

AlogP:
4.54

Polar Surface Area:
91.32

HBA:
7

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.41

DETAILS

ALA5281234

Name:
(2R)-N-[(3R)-1-methyl-8-(oxetan-3-yloxy)-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-Show More⌵

Mol. Formula:
C29H33F3N4O5

M.W.:
574.60

Type:
---

AlogP:
3.60

Polar Surface Area:
109.33

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.43

DETAILS

ALA5280809

Name:
2,2-dimethyl-N'-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazeShow More⌵

Mol. Formula:
C25H30N4O3

M.W.:
434.54

Type:
---

AlogP:
2.89

Polar Surface Area:
90.87

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5280169

Name:
N-(3,4-dichlorophenyl)-4-(imidazo[1,2-a]pyrazin-6-yl)piperazine-1-carboxamiShow More⌵

Mol. Formula:
C17H16Cl2N6O

M.W.:
391.26

Type:
---

AlogP:
3.39

Polar Surface Area:
65.77

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5280057

Name:
(2R)-5,5,5-trifluoro-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benShow More⌵

Mol. Formula:
C27H29F3N4O4

M.W.:
530.55

Type:
---

AlogP:
3.15

Polar Surface Area:
91.31

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5279751

Name:
2-(3,4-dichlorophenyl)-1-(4-(3-(2-(trifluoromethyl)pyridin-4-yl)-[1,2,4]triShow More⌵

Mol. Formula:
C23H18Cl2F3N7O

M.W.:
536.35

Type:
---

AlogP:
4.40

Polar Surface Area:
79.52

HBA:
7

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA5279729

Name:
2-(3,4-dichlorophenyl)-1-(4-(1-methyl-1H-pyrazolo[4,3-b]pyridin-5-yl)piperaShow More⌵

Mol. Formula:
C19H19Cl2N5O

M.W.:
404.30

Type:
---

AlogP:
3.17

Polar Surface Area:
54.26

HBA:
5

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5279221

Name:
1-(4-(1H-benzo[d]imidazol-6-yl)piperazin-1-yl)-2-(3,4-dichlorophenyl)ethanoShow More⌵

Mol. Formula:
C19H18Cl2N4O

M.W.:
389.29

Type:
---

AlogP:
3.76

Polar Surface Area:
52.23

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5278573

Name:
1-(4-(1H-pyrazolo[4,3-b]pyridin-5-yl)piperazin-1-yl)-2-(3,4-dichlorophenyl)Show More⌵

Mol. Formula:
C18H17Cl2N5O

M.W.:
390.27

Type:
---

AlogP:
3.16

Polar Surface Area:
65.12

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA5278308

Name:
2-(3,4-dichlorophenyl)-1-(4-(3-morpholino-[1,2,4]triazolo[4,3-b]pyridazin-6Show More⌵

Mol. Formula:
C21H23Cl2N7O2

M.W.:
476.37

Type:
---

AlogP:
2.16

Polar Surface Area:
79.10

HBA:
8

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.57

DETAILS