Compounds

ALA5267300

Name:
3-(2-Fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H16FN3

M.W.:
281.33

Type:
---

AlogP:
3.69

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.78

DETAILS

ALA5267219

Name:
3-(3,5-Dichlorophenyl)-7-(pyrrolidin-1-yl)quinolin-2-amine

Mol. Formula:
C19H17Cl2N3

M.W.:
358.27

Type:
---

AlogP:
5.39

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5266492

Name:
3-(3,5-Dichlorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H15Cl2N3

M.W.:
332.23

Type:
---

AlogP:
4.86

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5266105

Name:
N7,N7-Dimethyl-3-phenylquinoline-2,7-diamine

Mol. Formula:
C17H17N3

M.W.:
263.34

Type:
---

AlogP:
3.55

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5266087

Name:
3-(2-Bromophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H16BrN3

M.W.:
342.24

Type:
---

AlogP:
4.31

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.75

DETAILS

ALA5282456

Name:
3-(1-Methyl-1H-indol-3-yl)-7-(pyrrolidin-1-yl)quinolin-2-amine

Mol. Formula:
C22H22N4

M.W.:
342.45

Type:
---

AlogP:
4.58

Polar Surface Area:
47.08

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5281166

Name:
3-Furan-2-yl-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C15H15N3O

M.W.:
253.31

Type:
---

AlogP:
3.14

Polar Surface Area:
55.29

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5279286

Name:
3-(3,5-Dichlorophenyl)-7-(piperidin-1-yl)quinolin-2-amine

Mol. Formula:
C20H19Cl2N3

M.W.:
372.30

Type:
---

AlogP:
5.78

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA5279169

Name:
3-(3,5-Dichlorophenyl)-7-morpholinoquinolin-2-amine

Mol. Formula:
C19H17Cl2N3O

M.W.:
374.27

Type:
---

AlogP:
4.63

Polar Surface Area:
51.38

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5278212

Name:
3-(5-tert-butyl-1,3-benzoxazol-2-yl)-N7,N7-dimethyl-quinoline-2,7-diamine

Mol. Formula:
C22H24N4O

M.W.:
360.46

Type:
---

AlogP:
4.99

Polar Surface Area:
68.18

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5277993

Name:
3-(3,5-Dichlorophenyl)-N7-methylquinoline-2,7-diamine

Mol. Formula:
C16H13Cl2N3

M.W.:
318.21

Type:
---

AlogP:
4.83

Polar Surface Area:
50.94

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5277642

Name:
3-(1-Methyl-1H-indol-3-yl)-7-(piperidin-1-yl)quinolin-2-amine

Mol. Formula:
C23H24N4

M.W.:
356.47

Type:
---

AlogP:
4.97

Polar Surface Area:
47.08

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5276610

Name:
3-(4-Chlorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H16ClN3

M.W.:
297.79

Type:
---

AlogP:
4.20

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5274264

Name:
N7,N7-Dimethyl-3-thiophen-3-yl-quinoline-2,7-diamine

Mol. Formula:
C15H15N3S

M.W.:
269.37

Type:
---

AlogP:
3.61

Polar Surface Area:
42.15

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5273799

Name:
3-(2,5-Dichlorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H15Cl2N3

M.W.:
332.23

Type:
---

AlogP:
4.86

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5290790

Name:
3-(1-Methyl-1H-indol-3-yl)-7-(4-methylpiperazin-1-yl)quinolin-2-amine

Mol. Formula:
C23H25N5

M.W.:
371.49

Type:
---

AlogP:
3.73

Polar Surface Area:
50.32

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5290663

Name:
N7,N7-Dimethyl-3-phenylthiazol-2-yl-quinoline-2,7-diamine

Mol. Formula:
C20H18N4S

M.W.:
346.46

Type:
---

AlogP:
4.67

Polar Surface Area:
55.04

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5289451

Name:
3-Benzofuran-3-yl-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C19H17N3O

M.W.:
303.37

Type:
---

AlogP:
4.30

Polar Surface Area:
55.29

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5289115

Name:
3-(1-Methyl-1H-indol-3-yl)-7-morpholinoquinolin-2-amine

Mol. Formula:
C22H22N4O

M.W.:
358.45

Type:
---

AlogP:
3.81

Polar Surface Area:
56.31

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5288777

Name:
3-(3-Chlorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H16ClN3

M.W.:
297.79

Type:
---

AlogP:
4.20

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.77

DETAILS