Compounds

ALA5272183

Name:
3-(2,3-Dichlorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H15Cl2N3

M.W.:
332.23

Type:
---

AlogP:
4.86

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5271856

Name:
3-(3,5-Dichlorophenyl)-7-(4-methylpiperazin-1-yl)quinolin-2-amine

Mol. Formula:
C20H20Cl2N4

M.W.:
387.31

Type:
---

AlogP:
4.54

Polar Surface Area:
45.39

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5271609

Name:
3-Benzo[d]thiazol-2-yl-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C18H16N4S

M.W.:
320.42

Type:
---

AlogP:
4.16

Polar Surface Area:
55.04

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA5270715

Name:
3-[3-(N-methylindolyl)-N7,N7-dimethyl]-2,7-quinolinediamine

Mol. Formula:
C20H20N4

M.W.:
316.41

Type:
---

AlogP:
4.04

Polar Surface Area:
47.08

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.61

DETAILS

ALA5270247

Name:
3-(2,4-Dichlorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H15Cl2N3

M.W.:
332.23

Type:
---

AlogP:
4.86

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5270130

Name:
N7-Methyl-3-(4-(1-methyl-1H-indol-3-yl)phenyl)quinoline-2,7-diamine

Mol. Formula:
C19H18N4

M.W.:
302.38

Type:
---

AlogP:
4.02

Polar Surface Area:
55.87

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA5270105

Name:
N7,N7-Dimethyl-3-(1-methyl-1H-imidazol-2-yl)-quinoline-2,7-diamine

Mol. Formula:
C15H17N5

M.W.:
267.34

Type:
---

AlogP:
2.28

Polar Surface Area:
59.97

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5269837

Name:
N7,N7-Dimethyl-3-(pyridin-2-yl)quinoline-2,7-diamine

Mol. Formula:
C16H16N4

M.W.:
264.33

Type:
---

AlogP:
2.95

Polar Surface Area:
55.04

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5282456

Name:
3-(1-Methyl-1H-indol-3-yl)-7-(pyrrolidin-1-yl)quinolin-2-amine

Mol. Formula:
C22H22N4

M.W.:
342.45

Type:
---

AlogP:
4.58

Polar Surface Area:
47.08

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5281166

Name:
3-Furan-2-yl-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C15H15N3O

M.W.:
253.31

Type:
---

AlogP:
3.14

Polar Surface Area:
55.29

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.76

DETAILS

ALA5279286

Name:
3-(3,5-Dichlorophenyl)-7-(piperidin-1-yl)quinolin-2-amine

Mol. Formula:
C20H19Cl2N3

M.W.:
372.30

Type:
---

AlogP:
5.78

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.62

DETAILS

ALA5279169

Name:
3-(3,5-Dichlorophenyl)-7-morpholinoquinolin-2-amine

Mol. Formula:
C19H17Cl2N3O

M.W.:
374.27

Type:
---

AlogP:
4.63

Polar Surface Area:
51.38

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5278212

Name:
3-(5-tert-butyl-1,3-benzoxazol-2-yl)-N7,N7-dimethyl-quinoline-2,7-diamine

Mol. Formula:
C22H24N4O

M.W.:
360.46

Type:
---

AlogP:
4.99

Polar Surface Area:
68.18

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA5277993

Name:
3-(3,5-Dichlorophenyl)-N7-methylquinoline-2,7-diamine

Mol. Formula:
C16H13Cl2N3

M.W.:
318.21

Type:
---

AlogP:
4.83

Polar Surface Area:
50.94

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5276610

Name:
3-(4-Chlorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H16ClN3

M.W.:
297.79

Type:
---

AlogP:
4.20

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5274264

Name:
N7,N7-Dimethyl-3-thiophen-3-yl-quinoline-2,7-diamine

Mol. Formula:
C15H15N3S

M.W.:
269.37

Type:
---

AlogP:
3.61

Polar Surface Area:
42.15

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5273799

Name:
3-(2,5-Dichlorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H15Cl2N3

M.W.:
332.23

Type:
---

AlogP:
4.86

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5286937

Name:
3-(3,4-Dichlorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C17H15Cl2N3

M.W.:
332.23

Type:
---

AlogP:
4.86

Polar Surface Area:
42.15

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA5286763

Name:
3-Benzo[b]thiophen-3-yl-N7,N7-dimethylquinoline-2,7-diamine

Mol. Formula:
C19H17N3S

M.W.:
319.43

Type:
---

AlogP:
4.76

Polar Surface Area:
42.15

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5286483

Name:
3-(2-fluorophenyl)-1,5-naphthyridin-2-amine

Mol. Formula:
C14H10FN3

M.W.:
239.25

Type:
---

AlogP:
3.02

Polar Surface Area:
51.80

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.71

DETAILS