Compounds

ALA5269934

Name:
(R)-5-methyl-6-(2-methyl-1H-benzo[d]imidazol-5-yl)-4,5-dihydropyridazin-3(2Show More⌵

Mol. Formula:
C13H14N4O

M.W.:
242.28

Type:
---

AlogP:
1.73

Polar Surface Area:
70.14

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA5269656

Name:
4,4-Dimethyl-3-(4-morpholinophenyl)-1H-pyrazol-5(4H)-one

Mol. Formula:
C15H19N3O2

M.W.:
273.34

Type:
---

AlogP:
1.38

Polar Surface Area:
53.93

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA5268675

Name:
(R)-6-(4-(diethylamino)phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Mol. Formula:
C15H21N3O

M.W.:
259.35

Type:
---

AlogP:
2.39

Polar Surface Area:
44.70

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA5268188

Name:
3-(4-Aminophenyl)-4,4-dimethyl-1H-pyrazol-5(4H)-one

Mol. Formula:
C11H13N3O

M.W.:
203.25

Type:
---

AlogP:
1.13

Polar Surface Area:
67.48

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5268144

Name:
3-(4-Chlorophenyl)-4,4-dimethyl-1H-pyrazol-5(4H)-one

Mol. Formula:
C11H11ClN2O

M.W.:
222.68

Type:
---

AlogP:
2.20

Polar Surface Area:
41.46

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
Y

QED Weighted:
0.78

DETAILS

ALA5281139

Name:
(S)-6-(3,4-Difluorophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Mol. Formula:
C11H10F2N2O

M.W.:
224.21

Type:
---

AlogP:
1.82

Polar Surface Area:
41.46

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
Y

QED Weighted:
0.78

DETAILS

ALA5280872

Name:
(R)-6-(4-fluorophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Mol. Formula:
C11H11FN2O

M.W.:
206.22

Type:
---

AlogP:
1.69

Polar Surface Area:
41.46

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
Y

QED Weighted:
0.75

DETAILS

ALA5280390

Name:
(R)-6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Mol. Formula:
C11H13N3O

M.W.:
203.25

Type:
---

AlogP:
1.13

Polar Surface Area:
67.48

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.67

DETAILS

ALA5280347

Name:
(R)-6-(3-chloro-4-morpholinophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Mol. Formula:
C15H18ClN3O2

M.W.:
307.78

Type:
---

AlogP:
2.04

Polar Surface Area:
53.93

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.91

DETAILS

ALA5279968

Name:
(R)-6-(4-cyclohexenylphenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Mol. Formula:
C17H20N2O

M.W.:
268.36

Type:
---

AlogP:
3.50

Polar Surface Area:
41.46

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.88

DETAILS

ALA5279938

Name:
N-(2-(diethylamino)-5-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenShow More⌵

Mol. Formula:
C17H24N4O2

M.W.:
316.41

Type:
---

AlogP:
2.35

Polar Surface Area:
73.80

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.88

DETAILS

ALA5279566

Name:
(R)-N-(2-ethynyl-4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)Show More⌵

Mol. Formula:
C15H15N3O2

M.W.:
269.30

Type:
---

AlogP:
1.49

Polar Surface Area:
70.56

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA5278925

Name:
(+/-)-6-(4-(diethylamino)phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Mol. Formula:
C15H21N3O

M.W.:
259.35

Type:
---

AlogP:
2.39

Polar Surface Area:
44.70

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA5278913

Name:
(+/-)-6-(3,4-Difluorophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Mol. Formula:
C11H10F2N2O

M.W.:
224.21

Type:
---

AlogP:
1.82

Polar Surface Area:
41.46

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
Y

QED Weighted:
0.78

DETAILS

ALA5275174

Name:
(R)-6-(4-iodophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Mol. Formula:
C11H11IN2O

M.W.:
314.13

Type:
---

AlogP:
2.15

Polar Surface Area:
41.46

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
1

Passes Ro3:
N

QED Weighted:
0.79

DETAILS

ALA5273764

Name:
(R)-6-(4-(4H-1,2,4-triazol-4-yl)phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)Show More⌵

Mol. Formula:
C13H13N5O

M.W.:
255.28

Type:
---

AlogP:
1.13

Polar Surface Area:
72.17

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.87

DETAILS

ALA5273714

Name:
(+/-)-6-(3-Fluoro-4-morpholinophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-oShow More⌵

Mol. Formula:
C15H18FN3O2

M.W.:
291.33

Type:
---

AlogP:
1.52

Polar Surface Area:
53.93

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA5273160

Name:
(R)-N-(2-amino-4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)acShow More⌵

Mol. Formula:
C13H16N4O2

M.W.:
260.30

Type:
---

AlogP:
1.09

Polar Surface Area:
96.58

HBA:
4

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.69

DETAILS

ALA5284388

Name:
3-(4-(Diethylamino)phenyl)-4,4-dimethyl-1H-pyrazol-5(4H)-one

Mol. Formula:
C15H21N3O

M.W.:
259.35

Type:
---

AlogP:
2.39

Polar Surface Area:
44.70

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.90

DETAILS

ALA5284290

Name:
(R)-6-(4-(ethylamino)-3-nitrophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-onShow More⌵

Mol. Formula:
C13H16N4O3

M.W.:
276.30

Type:
---

AlogP:
1.89

Polar Surface Area:
96.63

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.65

DETAILS