Type:
Small molecule

AlogP:
1.43

Polar Surface Area:
79.18

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.37

Type:
Small molecule

AlogP:
1.90

Polar Surface Area:
98.49

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.49

Type:
Small molecule

AlogP:
3.46

Polar Surface Area:
258.30

HBA:
10

HBD:
9

#RO5 Violations:
2

#Rotatable Bonds:
29

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
3.46

Polar Surface Area:
258.30

HBA:
10

HBD:
9

#RO5 Violations:
2

#Rotatable Bonds:
29

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
2.68

Polar Surface Area:
258.30

HBA:
10

HBD:
9

#RO5 Violations:
2

#Rotatable Bonds:
27

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
3.46

Polar Surface Area:
258.30

HBA:
10

HBD:
9

#RO5 Violations:
2

#Rotatable Bonds:
29

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
4.31

Polar Surface Area:
186.11

HBA:
8

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
23

Passes Ro3:
N

QED Weighted:
0.04

Type:
Small molecule

AlogP:
2.68

Polar Surface Area:
258.30

HBA:
10

HBD:
9

#RO5 Violations:
2

#Rotatable Bonds:
27

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
4.31

Polar Surface Area:
186.11

HBA:
8

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
23

Passes Ro3:
N

QED Weighted:
0.04

Type:
Small molecule

AlogP:
5.10

Polar Surface Area:
186.11

HBA:
8

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
25

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
5.10

Polar Surface Area:
186.11

HBA:
8

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
25

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
2.68

Polar Surface Area:
258.30

HBA:
10

HBD:
9

#RO5 Violations:
2

#Rotatable Bonds:
27

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
2.68

Polar Surface Area:
258.30

HBA:
10

HBD:
9

#RO5 Violations:
2

#Rotatable Bonds:
27

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
0.53

Polar Surface Area:
165.21

HBA:
10

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.40

Type:
Small molecule

AlogP:
0.15

Polar Surface Area:
165.21

HBA:
10

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.40

Type:
Small molecule

AlogP:
-0.24

Polar Surface Area:
165.21

HBA:
10

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.41

Type:
Small molecule

AlogP:
-0.50

Polar Surface Area:
179.20

HBA:
10

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.43

Type:
Small molecule

AlogP:
5.92

Polar Surface Area:
38.77

HBA:
3

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.46

Type:
Small molecule

AlogP:
5.85

Polar Surface Area:
48.00

HBA:
4

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.40

Type:
Small molecule

AlogP:
5.74

Polar Surface Area:
48.00

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.45