Compounds

Type:
Unknown

AlogP:
5.51

Polar Surface Area:
46.92

HBA:
3

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4475127

Name:
3-(1H-indazol-6-yl)-4-methyl-N-(3-(4-methylpiperaz
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Mol. Formula:
C27H29N5O

M.W.:
439.56

Type:
Unknown

AlogP:
4.22

Polar Surface Area:
64.26

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4475050

Name:
N-(4-fluoro-3-(1H-indazol-6-yl)phenyl)-3-(trifluor
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Mol. Formula:
C21H13F4N3O

M.W.:
399.35

Type:
Unknown

AlogP:
5.64

Polar Surface Area:
57.78

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4474846

Name:
N-(3-(1H-indazol-6-yl)-2-methylphenyl)-3-(trifluor
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Mol. Formula:
C22H16F3N3O

M.W.:
395.38

Type:
Unknown

AlogP:
5.81

Polar Surface Area:
57.78

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4540198

Name:
N-(3-(1H-indazol-5-yl)phenyl)-3-(trifluoromethyl)b
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Mol. Formula:
C21H14F3N3O

M.W.:
381.36

Type:
Unknown

AlogP:
5.50

Polar Surface Area:
57.78

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4539769

Name:
3-(1H-indazol-6-yl)-4-methyl-N-(4-(4-methylpiperaz
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Mol. Formula:
C26H27N5O

M.W.:
425.54

Type:
Unknown

AlogP:
4.54

Polar Surface Area:
64.26

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4558274

Name:
3-(1H-indazol-6-yl)-4-methyl-N-(3-(4-methylpiperaz
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Mol. Formula:
C26H27N5O

M.W.:
425.54

Type:
Unknown

AlogP:
4.54

Polar Surface Area:
64.26

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4554690

Name:
N-(3-(3-amino-1H-indazol-6-yl)phenyl)-3-(trifluoro
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Mol. Formula:
C21H15F3N4O

M.W.:
396.37

Type:
Unknown

AlogP:
5.08

Polar Surface Area:
83.80

HBA:
3

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4551450

Name:
N-(3-(1H-indazol-6-yl)-4-methylphenyl)-3-(trifluor
Show More⌵

Mol. Formula:
C22H16F3N3O

M.W.:
395.38

Type:
Unknown

AlogP:
5.81

Polar Surface Area:
57.78

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4515189

Name:
N-(3-(3-amino-1H-indazol-5-yl)phenyl)-3-(trifluoro
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Mol. Formula:
C21H15F3N4O

M.W.:
396.37

Type:
Unknown

AlogP:
5.08

Polar Surface Area:
83.80

HBA:
3

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4574911

Name:
N-(3-(1H-indazol-6-yl)phenyl)-3-(trifluoromethyl)b
Show More⌵

Mol. Formula:
C21H14F3N3O

M.W.:
381.36

Type:
Unknown

AlogP:
5.50

Polar Surface Area:
57.78

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4588351

Name:
N-(5-(1H-indazol-6-yl)-2-methylphenyl)-3-(trifluor
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Mol. Formula:
C22H16F3N3O

M.W.:
395.38

Type:
Unknown

AlogP:
5.81

Polar Surface Area:
57.78

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4468582

Name:
3-(1H-indazol-6-yl)-4-methyl-N-(4-((4-methylpipera
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Mol. Formula:
C27H29N5O

M.W.:
439.56

Type:
Unknown

AlogP:
4.54

Polar Surface Area:
64.26

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4468220

Name:
3-(1H-indazol-6-yl)-N-(3-(trifluoromethyl)phenyl)b
Show More⌵

Mol. Formula:
C21H14F3N3O

M.W.:
381.36

Type:
Unknown

AlogP:
5.50

Polar Surface Area:
57.78

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.49

DETAILS

ALA4095191

Name:
N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoro
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Mol. Formula:
C27H29F3N6O

M.W.:
510.56

5 activity values

5 unique targets

Type:
Small molecule

AlogP:
4.06

Polar Surface Area:
64.60

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4470310

Name:
N-(3-(1H-indazol-6-yl)-5-methylphenyl)-3-(trifluor
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Mol. Formula:
C22H16F3N3O

M.W.:
395.38

Type:
Unknown

AlogP:
5.81

Polar Surface Area:
57.78

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4473922

Name:
3-(1H-indazol-6-yl)-4-methyl-N-(3-((4-methylpipera
Show More⌵

Mol. Formula:
C27H29N5O

M.W.:
439.56

Type:
Unknown

AlogP:
4.54

Polar Surface Area:
64.26

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4473495

Name:
N-(3-(1H-indazol-6-yl)-4-methoxyphenyl)-3-(trifluo
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Mol. Formula:
C22H16F3N3O2

M.W.:
411.38