Compounds

Type:
Unknown

AlogP:
4.41

Polar Surface Area:
68.76

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA4743396

Name:
3-phenethyl-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)
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Mol. Formula:
C21H25N5

M.W.:
347.47

Type:
Unknown

AlogP:
3.24

Polar Surface Area:
68.76

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA4742776

Name:
5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-3-(pyridazi
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Mol. Formula:
C18H21N7O

M.W.:
351.41

Type:
Unknown

AlogP:
1.82

Polar Surface Area:
103.77

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA4741426

Name:
3-((1-methyl-1H-imidazol-5-yl)methoxy)-5-(1-(piper
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Mol. Formula:
C18H23N7O

M.W.:
353.43

Type:
Unknown

AlogP:
1.76

Polar Surface Area:
95.81

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.73

DETAILS

ALA4741147

Name:
(R)-4-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-6-(1
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Mol. Formula:
C20H21Cl2FN6O

M.W.:
451.33

Type:
Unknown

AlogP:
4.43

Polar Surface Area:
90.88

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4741011

Name:
rac-2-(2-amino-5-(1-(piperidin-4-yl)-1H-pyrazol-4-
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Mol. Formula:
C21H22Cl2FN5O2

M.W.:
466.34

Type:
Unknown

AlogP:
4.01

Polar Surface Area:
98.22

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4762312

Name:
2-(2,6-dichloro-3-fluorophenyl)-4-(1-(piperidin-4-
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Mol. Formula:
C21H18Cl2FN5O

M.W.:
446.31

Type:
Unknown

AlogP:
5.31

Polar Surface Area:
81.90

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4760886

Name:
3-(4-chlorobenzyloxy)-5-(1-(piperidin-4-yl)-1H-pyr
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Mol. Formula:
C20H22ClN5O

M.W.:
383.88

Type:
Unknown

AlogP:
3.68

Polar Surface Area:
77.99

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4757394

Name:
3-(cyclohexylmethoxy)-5-(1-(piperidin-4-yl)-1H-pyr
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Mol. Formula:
C20H29N5O

M.W.:
355.49

Type:
Unknown

AlogP:
3.41

Polar Surface Area:
77.99

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.86

DETAILS

ALA4757177

Name:
(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1
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Mol. Formula:
C20H21Cl2FN6O

M.W.:
451.33

Type:
Unknown

AlogP:
4.43

Polar Surface Area:
90.88

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4757014

Name:
3-(2-methoxybenzyloxy)-5-(1-(piperidin-4-yl)-1H-py
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Mol. Formula:
C21H25N5O2

M.W.:
379.46

Type:
Unknown

AlogP:
3.04

Polar Surface Area:
87.22

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA4780336

Name:
3-(benzyloxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-y
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Mol. Formula:
C20H23N5O

M.W.:
349.44

Type:
Unknown

AlogP:
3.03

Polar Surface Area:
77.99

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA4779709

Name:
7-benzyl-4-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-5,
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Mol. Formula:
C23H28N6

M.W.:
388.52

Type:
Unknown

AlogP:
3.01

Polar Surface Area:
72.00

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.72

DETAILS

ALA4778070

Name:
3-(2-chlorobenzyloxy)-5-(1-(piperidin-4-yl)-1H-pyr
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Mol. Formula:
C20H22ClN5O

M.W.:
383.88

Type:
Unknown

AlogP:
3.68

Polar Surface Area:
77.99

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA4782953

Name:
3-(phenoxymethyl)-5-(1-(piperidin-4-yl)-1H-pyrazol
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Mol. Formula:
C20H23N5O

M.W.:
349.44

Type:
Unknown

AlogP:
3.03

Polar Surface Area:
77.99

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA4782872

Name:
2-amino-N-phenyl-5-(1-(piperidin-4-yl)-1H-pyrazol-
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Mol. Formula:
C20H22N6O

M.W.:
362.44

Type:
Unknown

AlogP:
2.70

Polar Surface Area:
97.86

HBA:
6

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.66

DETAILS

ALA4753188

Name:
2-(3-fluorophenyl)-5-(1-(piperidin-4-yl)-1H-pyrazo
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Mol. Formula:
C22H21FN6

M.W.:
388.45

Type:
Unknown

AlogP:
3.81

Polar Surface Area:
81.65

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4751159

Name:
5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-3-(2-(trifl
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Mol. Formula:
C21H22F3N5O

M.W.:
417.44

Type:
Unknown

AlogP:
4.05

Polar Surface Area:
77.99

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA4794231

Name:
rac-methyl 2-(2-amino-5-(1-(piperidin-4-yl)-1H-pyr
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Mol. Formula:
C22H22Cl2FN5O3

M.W.:
494.35

Type:
Unknown

AlogP:
4.19

Polar Surface Area:
104.29

HBA:
8

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4793638

Name:
5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-3-(3-(trifl
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Mol. Formula:
C21H22F3N5O

M.W.:
417.44