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  1. ALA4539731

    Name:
    1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-((1R,5S)-8-
    Show More

    Mol. Formula:
    C22H24F9N3O3

    M.W.:
    549.43

    Type:
    Unknown

    AlogP:
    4.82

    Polar Surface Area:
    45.25

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
  2. Type:
    Unknown

    AlogP:
    4.46

    Polar Surface Area:
    45.25

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.55

    DETAILS
  3. ALA5090898

    Name:
    1-(4'-fluorobiphenyl-4-yl)-4-(4-(furan-2-carbonyl)
    Show More

    Mol. Formula:
    C25H24FN3O3

    M.W.:
    433.48

    Type:
    Unknown

    AlogP:
    3.65

    Polar Surface Area:
    57.00

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.63

    DETAILS
  4. ALA5090045

    Name:
    (R)-1-(3-(2-fluoro-4-methylpyridin-3-yl)phenyl)-4-
    Show More

    Mol. Formula:
    C24H24FN5O2S

    M.W.:
    465.55

    Type:
    Unknown

    AlogP:
    3.22

    Polar Surface Area:
    69.64

    HBA:
    6

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.55

    DETAILS
  5. ALA5089959

    Name:
    1-(4-((R)-3-fluoropyrrolidin-1-yl)phenyl)-4-(4-(fu
    Show More

    Mol. Formula:
    C23H27FN4O3

    M.W.:
    426.49

    Type:
    Unknown

    AlogP:
    2.39

    Polar Surface Area:
    60.24

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.75

    DETAILS
  6. ALA5089326

    Name:
    (R)-1-(4'-fluorobiphenyl-4-yl)-4-(4-(furan-2-carbo
    Show More

    Mol. Formula:
    C25H24FN3O3

    M.W.:
    433.48

    Type:
    Unknown

    AlogP:
    3.65

    Polar Surface Area:
    57.00

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.63

    DETAILS
  7. ALA5087100

    Name:
    1-(3-(2-fluoropyridin-3-yl)phenyl)-4-(4-(pyrimidin
    Show More

    Mol. Formula:
    C23H23FN6O

    M.W.:
    418.48

    Type:
    Unknown

    AlogP:
    2.61

    Polar Surface Area:
    65.46

    HBA:
    6

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.61

    DETAILS
  8. ALA5086006

    Name:
    1-(3'-methoxybiphenyl-3-yl)-4-(4-(pyrimidin-2-yl)p
    Show More

    Mol. Formula:
    C25H27N5O2

    M.W.:
    429.52

    Type:
    Unknown

    AlogP:
    3.08

    Polar Surface Area:
    61.80

    HBA:
    6

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.62

    DETAILS
  9. ALA5084732

    Name:
    1-(3-((S)-3-fluoropyrrolidin-1-yl)phenyl)-4-(4-(py
    Show More

    Mol. Formula:
    C22H27FN6O

    M.W.:
    410.50

    Type:
    Unknown

    AlogP:
    1.95

    Polar Surface Area:
    55.81

    HBA:
    6

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.77

    DETAILS
  10. ALA5084467

    Name:
    1-(3'-methoxybiphenyl-4-yl)-4-(4-(pyrimidin-2-yl)p
    Show More

    Mol. Formula:
    C25H27N5O2

    M.W.:
    429.52

    Type:
    Unknown

    AlogP:
    3.08

    Polar Surface Area:
    61.80

    HBA:
    6

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.62

    DETAILS
  11. ALA5084120

    Name:
    4-(4-(furan-2-carbonyl)piperazin-1-yl)-1-(3'-metho
    Show More

    Mol. Formula:
    C26H27N3O4

    M.W.:
    445.52

    Type:
    Unknown

    AlogP:
    3.52

    Polar Surface Area:
    66.23

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.60

    DETAILS
  12. ALA5083362

    Name:
    1-(3-(6-fluoropyridin-3-yl)phenyl)-4-(4-(pyrimidin
    Show More

    Mol. Formula:
    C23H23FN6O

    M.W.:
    418.48

    Type:
    Unknown

    AlogP:
    2.61

    Polar Surface Area:
    65.46

    HBA:
    6

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.61

    DETAILS
  13. ALA5083252

    Name:
    1-(3-((R)-3-fluoropyrrolidin-1-yl)phenyl)-4-(4-(fu
    Show More

    Mol. Formula:
    C23H27FN4O3

    M.W.:
    426.49

    Type:
    Unknown

    AlogP:
    2.39

    Polar Surface Area:
    60.24

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.75

    DETAILS
  14. ALA5082445

    Name:
    1-(2'-methoxybiphenyl-3-yl)-4-(4-(pyrimidin-2-yl)p
    Show More

    Mol. Formula:
    C25H27N5O2

    M.W.:
    429.52

    Type:
    Unknown

    AlogP:
    3.08

    Polar Surface Area:
    61.80

    HBA:
    6

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.62

    DETAILS
  15. ALA5082157

    Name:
    1-(4-(6-fluoropyridin-3-yl)phenyl)-4-(4-(furan-2-c
    Show More

    Mol. Formula:
    C24H23FN4O3

    M.W.:
    434.47

    Type:
    Unknown

    AlogP:
    3.04

    Polar Surface Area:
    69.89

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.59

    DETAILS
  16. ALA5082041

    Name:
    4-(4-(furan-2-carbonyl)piperazin-1-yl)-1-(3'-metho
    Show More

    Mol. Formula:
    C26H27N3O4

    M.W.:
    445.52

    Type:
    Unknown

    AlogP:
    3.52

    Polar Surface Area:
    66.23

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.60

    DETAILS
  17. ALA5080859

    Name:
    1-(3-((R)-3-fluoropyrrolidin-1-yl)phenyl)-4-(4-(py
    Show More

    Mol. Formula:
    C22H27FN6O

    M.W.:
    410.50

    Type:
    Unknown

    AlogP:
    1.95

    Polar Surface Area:
    55.81

    HBA:
    6

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.77

    DETAILS
  18. ALA5078235

    Name:
    4-(4-(furan-2-carbonyl)piperazin-1-yl)-1-(2'-metho
    Show More

    Mol. Formula:
    C26H27N3O4

    M.W.:
    445.52

    Type:
    Unknown

    AlogP:
    3.52

    Polar Surface Area:
    66.23

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.60

    DETAILS
  19. ALA5078113

    Name:
    (S)-1-(4'-fluorobiphenyl-4-yl)-4-(4-(furan-2-carbo
    Show More

    Mol. Formula:
    C25H24FN3O3

    M.W.:
    433.48

    Type:
    Unknown

    AlogP:
    3.65

    Polar Surface Area:
    57.00

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.63

    DETAILS
  20. ALA5076234

    Name:
    1-(3'-fluorobiphenyl-3-yl)-4-(4-(furan-2-carbonyl)
    Show More

    Mol. Formula:
    C25H24FN3O3

    M.W.:
    433.48

    Type:
    Unknown

    AlogP:
    3.65

    Polar Surface Area:
    57.00

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.63

    DETAILS
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