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  1. ALA4552597

    Name:
    2-Amino-N-(2-chloro-5-{1-[1-(N,N-dimethylglycyl)pi
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    Mol. Formula:
    C22H26ClN7O3

    M.W.:
    471.95

    Type:
    Unknown

    AlogP:
    2.75

    Polar Surface Area:
    122.52

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS
  2. ALA4551539

    Name:
    2-Amino-N-{2-chloro-5-[6-(hexahydropyrrolo[3,4-c]p
    Show More

    Mol. Formula:
    C22H23ClN6O2

    M.W.:
    438.92

    Type:
    Unknown

    AlogP:
    2.88

    Polar Surface Area:
    109.31

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.56

    DETAILS
  3. ALA4536252

    Name:
    2-Amino-N-(2-chloro-5-{6-[3-(dimethylamino)propoxy
    Show More

    Mol. Formula:
    C20H22ClN5O3

    M.W.:
    415.88

    Type:
    Unknown

    AlogP:
    3.56

    Polar Surface Area:
    106.51

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.54

    DETAILS
  4. ALA4514185

    Name:
    2-Amino-N-{2-chloro-5-[2-(piperidin-4-yloxy)pyrimi
    Show More

    Mol. Formula:
    C19H19ClN6O3

    M.W.:
    414.85

    Type:
    Unknown

    AlogP:
    2.75

    Polar Surface Area:
    128.19

    HBA:
    8

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.58

    DETAILS
  5. ALA4483613

    Name:
    2-Amino-N-(2-chloro-5-{1-[1(N,N-dimethyl-beta-alan
    Show More

    Mol. Formula:
    C23H28ClN7O3

    M.W.:
    485.98

    Type:
    Unknown

    AlogP:
    3.14

    Polar Surface Area:
    122.52

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  6. ALA4482890

    Name:
    2-Amino-N-{2-chloro-5-[2-(piperidin-4-yloxy)-1,3-t
    Show More

    Mol. Formula:
    C18H18ClN5O3S

    M.W.:
    419.89

    Type:
    Unknown

    AlogP:
    3.42

    Polar Surface Area:
    115.30

    HBA:
    8

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.58

    DETAILS
  7. ALA4476811

    Name:
    2-Amino-N-[2-chloro-5-(1-{[1-(N,N-dimethyl-beta-al
    Show More

    Mol. Formula:
    C22H26ClN7O3

    M.W.:
    471.95

    Type:
    Unknown

    AlogP:
    2.44

    Polar Surface Area:
    122.52

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.52

    DETAILS
  8. ALA4474352

    Name:
    2-Amino-N-(2-chloro-5-(6-(3-(methylamino)propoxy)p
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    Mol. Formula:
    C19H20ClN5O3

    M.W.:
    401.85

    Type:
    Unknown

    AlogP:
    3.21

    Polar Surface Area:
    115.30

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
  9. ALA4545699

    Name:
    2-Amino-N-[2-chloro-5-(1-{1-[4-(dimethylamino)buta
    Show More

    Mol. Formula:
    C24H30ClN7O3

    M.W.:
    500.00

    Type:
    Unknown

    AlogP:
    3.53

    Polar Surface Area:
    122.52

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.49

    DETAILS
  10. ALA4543878

    Name:
    2-Amino-N-[4-chloro-4'-(piperazin-1-yl)biphenyl-3-
    Show More

    Mol. Formula:
    C20H20ClN5O2

    M.W.:
    397.87

    Type:
    Unknown

    AlogP:
    3.24

    Polar Surface Area:
    96.42

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.63

    DETAILS
  11. ALA4519614

    Name:
    2-Amino-N-[2-chloro-5-(4-{[4-(dimethylamino)piperi
    Show More

    Mol. Formula:
    C21H25ClN6O2S

    M.W.:
    460.99

    Type:
    Unknown

    AlogP:
    3.81

    Polar Surface Area:
    100.52

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.58

    DETAILS
  12. ALA4516567

    Name:
    2-Amino-N-{2-chloro-5-[6-(piperidin-4-yloxy)pyridi
    Show More

    Mol. Formula:
    C20H20ClN5O3

    M.W.:
    413.87

    Type:
    Unknown

    AlogP:
    3.36

    Polar Surface Area:
    115.30

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.59

    DETAILS
  13. ALA4516565

    Name:
    2-Amino-N-(2-chloro-5-{2-[3-(dimethylamino)propoxy
    Show More

    Mol. Formula:
    C18H20ClN5O3S

    M.W.:
    421.91

    Type:
    Unknown

    AlogP:
    3.62

    Polar Surface Area:
    106.51

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  14. ALA4516092

    Name:
    2-Amino-N-{2-chloro-5-[6-(piperazin-1-ylmethyl)pyr
    Show More

    Mol. Formula:
    C20H21ClN6O2

    M.W.:
    412.88

    Type:
    Unknown

    AlogP:
    2.63

    Polar Surface Area:
    109.31

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.59

    DETAILS
  15. ALA4586958

    Name:
    2-amino-N-{2-chloro-5-[2-({4-[(methylamino)methyl]
    Show More

    Mol. Formula:
    C21H25ClN6O2S

    M.W.:
    460.99

    Type:
    Unknown

    AlogP:
    3.72

    Polar Surface Area:
    109.31

    HBA:
    8

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.49

    DETAILS
  16. ALA4585820

    Name:
    2-Amino-N-(2-chloro-5-{1-[2-(piperazin-1-yl)ethyl]
    Show More

    Mol. Formula:
    C19H22ClN7O2

    M.W.:
    415.89

    Type:
    Unknown

    AlogP:
    1.93

    Polar Surface Area:
    114.24

    HBA:
    8

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.56

    DETAILS
  17. ALA4581822

    Name:
    2-Amino-N-[2-chloro-5-(2-{[3-(methylamino)piperidi
    Show More

    Mol. Formula:
    C20H23ClN6O2S

    M.W.:
    446.96

    Type:
    Unknown

    AlogP:
    3.47

    Polar Surface Area:
    109.31

    HBA:
    8

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  18. ALA4575613

    Name:
    2-Amino-N-[2-chloro-5-(6-{[(1-methylpiperidin-4-yl
    Show More

    Mol. Formula:
    C22H25ClN6O2

    M.W.:
    440.94

    Type:
    Unknown

    AlogP:
    3.41

    Polar Surface Area:
    109.31

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.54

    DETAILS
  19. ALA4569580

    Name:
    2-Amino-N-(2-chloro-5-{1-[2-(3-methylpiperazin-1-y
    Show More

    Mol. Formula:
    C20H22ClN7O3

    M.W.:
    443.90

    Type:
    Unknown

    AlogP:
    1.85

    Polar Surface Area:
    131.31

    HBA:
    8

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.55

    DETAILS
  20. ALA4566697

    Name:
    2-Amino-N-(2-chloro-5-{1-[1-(2-hydroxyethyl)piperi
    Show More

    Mol. Formula:
    C20H23ClN6O3

    M.W.:
    430.90

    Type:
    Unknown

    AlogP:
    2.66

    Polar Surface Area:
    122.44

    HBA:
    8

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.55

    DETAILS
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