Compounds

Type:
Unknown

AlogP:
5.24

Polar Surface Area:
100.99

HBA:
5

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4476596

Name:
1-(5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'-bipy
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Mol. Formula:
C24H22ClN5O2

M.W.:
447.93

7 activity values

7 unique targets

Type:
Unknown

AlogP:
5.03

Polar Surface Area:
95.00

HBA:
5

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4475779

Name:
2-(1-(4-(5-((5-isopropyl-1,3,4-oxadiazol-2-yl)amin
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Mol. Formula:
C23H27N5O3

M.W.:
421.50

5 activity values

Type:
Unknown

AlogP:
4.69

Polar Surface Area:
104.38

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA4540189

Name:
2-((1r,4r)-4-(4-(5-(5-ethyl-1,3,4-oxadiazol-2-ylam
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Mol. Formula:
C23H26N4O3

M.W.:
406.49

Type:
Unknown

AlogP:
5.19

Polar Surface Area:
101.14

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.56

DETAILS

ALA4524803

Name:
trans-2-(4-(1-(5-(5-methoxy-1H-imidazo[4,5-b]pyrid
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Mol. Formula:
C25H31N5O4

M.W.:
465.55

Type:
Unknown

AlogP:
4.05

Polar Surface Area:
113.46

HBA:
7

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA4534257

Name:
1-((5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'-bip
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Mol. Formula:
C22H18ClN5O2

M.W.:
419.87

Type:
Unknown

AlogP:
4.62

Polar Surface Area:
103.79

HBA:
5

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4531443

Name:
2-((1r,4r)-4-(4'-(5-chloro-1H-benzo[d]imidazol-2-y
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Mol. Formula:
C27H25ClN2O2

M.W.:
444.96

4 activity values

4 unique targets

Type:
Unknown

AlogP:
7.30

Polar Surface Area:
65.98

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA4531344

Name:
trans-2-(4-(1-(5-(6-(trifluoromethyl)-3H-imidazo[4
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Mol. Formula:
C25H28F3N5O3

M.W.:
503.53

Type:
Unknown

AlogP:
5.06

Polar Surface Area:
104.23

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4561313

Name:
cis-2-(4-(5-(5-cyano-1H-benzo[d]imidazol-2-yl)-2,3
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Mol. Formula:
C26H23N5O3

M.W.:
453.50

Type:
Unknown

AlogP:
4.97

Polar Surface Area:
124.78

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

DETAILS

ALA4557603

Name:
2-((1r,4r)-4-(4'-(5-(trifluoromethyl)-1H-benzo[d]i
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Mol. Formula:
C28H25F3N2O2

M.W.:
478.51

4 activity values

4 unique targets

Type:
Unknown

AlogP:
7.66

Polar Surface Area:
65.98

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA4555623

Name:
2-(4-(4-(5-(2-ethyl-4-methyloxazole-5-carboxamido)
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Mol. Formula:
C27H29N3O5

M.W.:
475.55

Type:
Unknown

AlogP:
4.92

Polar Surface Area:
114.55

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4554202

Name:
rac-2-(5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'-
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Mol. Formula:
C24H22ClN5O2

M.W.:
447.93

Type:
Unknown

AlogP:
5.40

Polar Surface Area:
103.79

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.38

DETAILS

ALA4554065

Name:
2-((1r,4r)-4-(4-(5-(5-cyclobutyl-1,3,4-thiadiazol-
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Mol. Formula:
C25H28N4O2S

M.W.:
448.59

Type:
Unknown

AlogP:
6.36

Polar Surface Area:
88.00

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA4530290

Name:
cis-2-(4-(5-(6-(trifluoromethyl)-3H-imidazo[4,5-b]
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Mol. Formula:
C25H22F3N5O3

M.W.:
497.48

7 activity values

Type:
Unknown

AlogP:
5.51

Polar Surface Area:
113.88

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4527336

Name:
2-((1r,4r)-4-(4-(5-(5-tert-butyl-1,3,4-oxadiazol-2
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Mol. Formula:
C25H30N4O3

M.W.:
434.54

2 activity values

2 unique targets

Type:
Unknown

AlogP:
5.92

Polar Surface Area:
101.14

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.50

DETAILS

ALA4527253

Name:
rac-2-((5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'
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Mol. Formula:
C22H17ClN4O3

M.W.:
420.86

Type:
Unknown

AlogP:
4.44

Polar Surface Area:
100.99

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4527223

Name:
3-((5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'-bip
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Mol. Formula:
C22H17ClN4O4

M.W.:
436.86

Type:
Unknown

AlogP:
3.82

Polar Surface Area:
110.22

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.47

DETAILS

ALA4525823

Name:
2-(4-(pyridin-3-yl)phenyl)-5-(trifluoromethyl)-1H-
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Mol. Formula:
C19H12F3N3

M.W.:
339.32

Type:
Unknown

AlogP:
5.31

Polar Surface Area:
41.57

HBA:
2

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.54

DETAILS

ALA4516271

Name:
rac-1-(5-(5-chloro-1H-benzo[d]imidazol-2-yl)-2,3'-
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Mol. Formula:
C24H22ClN5O2

M.W.:
447.93

Type:
Unknown

AlogP:
5.03

Polar Surface Area:
95.00

HBA:
5

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4575608

Name:
4'-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)b
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Mol. Formula:
C20H13F3N2O

M.W.:
354.33