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  1. ALA4548741

    Name:
    4-Hydroxy-3-{1-[2-methyl-6-(trifluoromethyl)pyrimi
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    Mol. Formula:
    C18H18F6N6O2

    M.W.:
    464.37

    Type:
    Unknown

    AlogP:
    3.00

    Polar Surface Area:
    107.03

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.59

    DETAILS
  2. ALA4550163

    Name:
    cis-3-{1-[5-(Difluoromethoxy)pyridin-2-yl]piperidi
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    Mol. Formula:
    C18H18F5N5O3

    M.W.:
    447.36

    Type:
    Unknown

    AlogP:
    2.75

    Polar Surface Area:
    103.37

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.62

    DETAILS
  3. ALA4524823

    Name:
    4-Hydroxy-3-[1-(4-methylpyridin-2-yl)piperidin-4-y
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    Mol. Formula:
    C18H20F3N5O2

    M.W.:
    395.39

    Type:
    Unknown

    AlogP:
    2.59

    Polar Surface Area:
    94.14

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.73

    DETAILS
  4. ALA4556164

    Name:
    (+)-cis-5-Hydroxy-4-(trifluoromethyl)-3-{1-[2-(tri
    Show More

    Mol. Formula:
    C17H16F6N6O2

    M.W.:
    450.34

    Type:
    Unknown

    AlogP:
    2.56

    Polar Surface Area:
    107.03

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.61

    DETAILS
  5. ALA4556066

    Name:
    cis-5-Hydroxy-4-(trifluoromethyl)-3-{1-[6-(trifluo
    Show More

    Mol. Formula:
    C18H17F6N5O2

    M.W.:
    449.36

    Type:
    Unknown

    AlogP:
    3.17

    Polar Surface Area:
    94.14

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.61

    DETAILS
  6. ALA4541184

    Name:
    4-Hydroxy-3-[1-(6-phenylpyridazin-3-yl)piperidin-4
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    Mol. Formula:
    C22H21F3N6O2

    M.W.:
    458.44

    Type:
    Unknown

    AlogP:
    3.34

    Polar Surface Area:
    107.03

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.56

    DETAILS
  7. ALA4560530

    Name:
    Methyl 6-{4-[4-hydroxy-6-oxo-4-(trifluoromethyl)-4
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    Mol. Formula:
    C20H19F6N5O4

    M.W.:
    507.39

    Type:
    Unknown

    AlogP:
    3.09

    Polar Surface Area:
    120.44

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  8. ALA4558558

    Name:
    (cis)-5-hydroxy-4-(trifluoromethyl)-3-{1-[6-(trifl
    Show More

    Mol. Formula:
    C17H16F6N6O2

    M.W.:
    450.34

    Type:
    Unknown

    AlogP:
    2.56

    Polar Surface Area:
    107.03

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.61

    DETAILS
  9. ALA4558170

    Name:
    3-[1-(4-Fluorophenyl)piperidin-4-yl]-4-hydroxy-4-(
    Show More

    Mol. Formula:
    C18H18F4N4O2

    M.W.:
    398.36

    Type:
    Unknown

    AlogP:
    3.02

    Polar Surface Area:
    81.25

    HBA:
    4

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.68

    DETAILS
  10. ALA4557346

    Name:
    4-Hydroxy-4-(trifluoromethyl)-3-{1-[4-(trifluorome
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    Mol. Formula:
    C16H15F6N5O2S

    M.W.:
    455.38

    Type:
    Unknown

    AlogP:
    3.36

    Polar Surface Area:
    94.14

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.60

    DETAILS
  11. ALA4554654

    Name:
    4-Hydroxy-3-[1-(6-methoxypyridazin-3-yl)piperidin-
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    Mol. Formula:
    C17H19F3N6O3

    M.W.:
    412.37

    Type:
    Unknown

    AlogP:
    1.68

    Polar Surface Area:
    116.26

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.70

    DETAILS
  12. ALA4554081

    Name:
    2-Chloro-6-{4-[4-hydroxy-6-oxo-4-(trifluoromethyl)
    Show More

    Mol. Formula:
    C18H16ClF3N6O2

    M.W.:
    440.81

    Type:
    Unknown

    AlogP:
    2.81

    Polar Surface Area:
    117.93

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.62

    DETAILS
  13. ALA4539903

    Name:
    cis-5-Hydroxy-3-{1-[4-(piperidin-1-ylcarbonyl)-5-(
    Show More

    Mol. Formula:
    C24H26F6N6O3

    M.W.:
    560.50

    Type:
    Unknown

    AlogP:
    3.79

    Polar Surface Area:
    114.45

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.49

    DETAILS
  14. ALA4538294

    Name:
    3-[1-(5-Bromopyridin-2-yl)piperidin-4-yl]-4-hydrox
    Show More

    Mol. Formula:
    C17H17BrF3N5O2

    M.W.:
    460.25

    Type:
    Unknown

    AlogP:
    3.04

    Polar Surface Area:
    94.14

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.64

    DETAILS
  15. ALA4537945

    Name:
    (+)-cis-5-Hydroxy-4-(trifluoromethyl)-3-{1-[5-(tri
    Show More

    Mol. Formula:
    C15H14F6N6O2S

    M.W.:
    456.37

    Type:
    Unknown

    AlogP:
    2.62

    Polar Surface Area:
    107.03

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.60

    DETAILS
  16. ALA4536836

    Name:
    (+)-3-Fluoro-5-{4-[cis-5-hydroxy-6-oxo-4-(trifluor
    Show More

    Mol. Formula:
    C18H16F4N6O2

    M.W.:
    424.36

    Type:
    Unknown

    AlogP:
    2.16

    Polar Surface Area:
    117.93

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.64

    DETAILS
  17. ALA4536600

    Name:
    4-Hydroxy-3-{1-[6-(propan-2-yloxy)pyridazin-3-yl]p
    Show More

    Mol. Formula:
    C19H23F3N6O3

    M.W.:
    440.43

    Type:
    Unknown

    AlogP:
    2.46

    Polar Surface Area:
    116.26

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.67

    DETAILS
  18. ALA4536394

    Name:
    4-Hydroxy-4-(trifluoromethyl)-3-{1-[4-(trifluorome
    Show More

    Mol. Formula:
    C17H16F6N6O2

    M.W.:
    450.34

    Type:
    Unknown

    AlogP:
    2.69

    Polar Surface Area:
    107.03

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.61

    DETAILS
  19. ALA4536350

    Name:
    3-[1-(6-Chloropyridazin-3-yl)piperidin-4-yl]-4-hyd
    Show More

    Mol. Formula:
    C16H16ClF3N6O2

    M.W.:
    416.79

    Type:
    Unknown

    AlogP:
    2.33

    Polar Surface Area:
    107.03

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.69

    DETAILS
  20. ALA4536147

    Name:
    3-{1-[6-chloro-3-(trifluoromethyl)pyridin-2-yl]pip
    Show More

    Mol. Formula:
    C18H16ClF6N5O2

    M.W.:
    483.80

    Type:
    Unknown

    AlogP:
    3.95

    Polar Surface Area:
    94.14

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
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