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  1. ALA4879170

    Name:
    Ethyl 6-((2,8-diazaspiro[4.5]decan-2-yl)methyl)-4-
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    Mol. Formula:
    C25H29BrFN5O2S

    M.W.:
    562.51

    Type:
    Unknown

    AlogP:
    4.03

    Polar Surface Area:
    78.85

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.52

    DETAILS
  2. ALA4878654

    Name:
    Ethyl 4-(2-bromo-4-fluorophenyl)-6-((8-oxo-2,7-dia
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    Mol. Formula:
    C24H25BrFN5O3S

    M.W.:
    562.46

    Type:
    Unknown

    AlogP:
    3.17

    Polar Surface Area:
    95.92

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  3. ALA4876680

    Name:
    Ethyl 6-((2,7-diazaspiro[3.5]nonan-7-yl)methyl)-4-
    Show More

    Mol. Formula:
    C24H27BrFN5O2S

    M.W.:
    548.48

    Type:
    Unknown

    AlogP:
    3.64

    Polar Surface Area:
    78.85

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.54

    DETAILS
  4. ALA4875299

    Name:
    Ethyl 4-(2-bromo-4-fluorophenyl)-6-((3-oxo-2,8-dia
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    Mol. Formula:
    C25H27BrFN5O3S

    M.W.:
    576.49

    Type:
    Unknown

    AlogP:
    3.56

    Polar Surface Area:
    95.92

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.51

    DETAILS
  5. ALA4872969

    Name:
    Ethyl 4-(2-bromo-4-fluorophenyl)-6-((7-oxo-2,6-dia
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    Mol. Formula:
    C23H23BrFN5O3S

    M.W.:
    548.44

    Type:
    Unknown

    AlogP:
    2.77

    Polar Surface Area:
    95.92

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.54

    DETAILS
  6. ALA4872833

    Name:
    Ethyl 6-((7-benzyl-6,8-dioxo-2,7-diazaspiro[4.4]no
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    Mol. Formula:
    C31H29BrFN5O4S

    M.W.:
    666.57

    Type:
    Unknown

    AlogP:
    4.60

    Polar Surface Area:
    104.20

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.28

    DETAILS
  7. ALA4872598

    Name:
    Tert-butyl 2-((6-(2-bromo-4-fluorophenyl)-5-(ethox
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    Mol. Formula:
    C30H37BrFN5O4S

    M.W.:
    662.63

    Type:
    Unknown

    AlogP:
    5.68

    Polar Surface Area:
    96.36

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.40

    DETAILS
  8. ALA4868819

    Name:
    Ethyl 6-((3,9-diazaspiro[5.5]undecan-3-yl)methyl)-
    Show More

    Mol. Formula:
    C26H31BrFN5O2S

    M.W.:
    576.54

    Type:
    Unknown

    AlogP:
    4.42

    Polar Surface Area:
    78.85

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
  9. ALA4867645

    Name:
    Tert-butyl 6-((6-(2-bromo-4-fluorophenyl)-5-(ethox
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    Mol. Formula:
    C28H31BrFN5O5S

    M.W.:
    648.55

    Type:
    Unknown

    AlogP:
    4.42

    Polar Surface Area:
    113.43

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS
  10. ALA4867571

    Name:
    Tert-butyl 9-((6-(2-bromo-4-fluorophenyl)-5-(ethox
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    Mol. Formula:
    C31H39BrFN5O4S

    M.W.:
    676.65

    Type:
    Unknown

    AlogP:
    6.07

    Polar Surface Area:
    96.36

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  11. ALA4866011

    Name:
    Ethyl 6-((2,6-diazaspiro[3.4]octan-6-yl)methyl)-4-
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    Mol. Formula:
    C23H25BrFN5O2S

    M.W.:
    534.45

    Type:
    Unknown

    AlogP:
    3.25

    Polar Surface Area:
    78.85

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.55

    DETAILS
  12. ALA4865922

    Name:
    Tert-butyl 7-((6-(2-bromo-4-fluorophenyl)-5-(ethox
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    Mol. Formula:
    C29H35BrFN5O4S

    M.W.:
    648.60

    Type:
    Unknown

    AlogP:
    5.29

    Polar Surface Area:
    96.36

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  13. ALA4863861

    Name:
    Ethyl 6-((2,6-diazaspiro[3.3]heptan-2-yl)methyl)-4
    Show More

    Mol. Formula:
    C22H23BrFN5O2S

    M.W.:
    520.43

    Type:
    Unknown

    AlogP:
    2.86

    Polar Surface Area:
    78.85

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS
  14. ALA4863182

    Name:
    Ethyl 6-((2,7-diazaspiro[4.4]nonan-2-yl)methyl)-4-
    Show More

    Mol. Formula:
    C24H27BrFN5O2S

    M.W.:
    548.48

    Type:
    Unknown

    AlogP:
    3.64

    Polar Surface Area:
    78.85

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.54

    DETAILS
  15. ALA4859141

    Name:
    Ethyl 6-((2-amino-7-azaspiro[3.5]nonan-7-yl)methyl
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    Mol. Formula:
    C25H29BrFN5O2S

    M.W.:
    562.51

    Type:
    Unknown

    AlogP:
    4.16

    Polar Surface Area:
    92.84

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.51

    DETAILS
  16. ALA4857913

    Name:
    Tert-butyl 6-((6-(2-bromo-4-fluorophenyl)-5-(ethox
    Show More

    Mol. Formula:
    C28H33BrFN5O4S

    M.W.:
    634.57

    Type:
    Unknown

    AlogP:
    4.90

    Polar Surface Area:
    96.36

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  17. ALA4857897

    Name:
    Tert-butyl 7-((6-(2-bromo-4-fluorophenyl)-5-(ethox
    Show More

    Mol. Formula:
    C29H35BrFN5O4S

    M.W.:
    648.60

    Type:
    Unknown

    AlogP:
    5.29

    Polar Surface Area:
    96.36

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  18. ALA4857777

    Name:
    Ethyl 4-(2-bromo-4-fluorophenyl)-6-((1-oxo-2,7-dia
    Show More

    Mol. Formula:
    C24H25BrFN5O3S

    M.W.:
    562.46

    Type:
    Unknown

    AlogP:
    3.17

    Polar Surface Area:
    95.92

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  19. ALA4860746

    Name:
    Ethyl 4-(2-bromo-4-fluorophenyl)-6-((1-oxo-2,7-dia
    Show More

    Mol. Formula:
    C24H25BrFN5O3S

    M.W.:
    562.46

    Type:
    Unknown

    AlogP:
    3.17

    Polar Surface Area:
    95.92

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
  20. ALA4860256

    Name:
    Tert-butyl 6-((6-(2-bromo-4-fluorophenyl)-5-(ethox
    Show More

    Mol. Formula:
    C27H31BrFN5O4S

    M.W.:
    620.54

    Type:
    Unknown

    AlogP:
    4.51

    Polar Surface Area:
    96.36

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.48

    DETAILS
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