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  1. ALA4475369

    Name:
    4-((2-Acrylamidophenyl)amino)-N-(4,5-dimethoxy-2-m
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    Mol. Formula:
    C34H38N8O4

    M.W.:
    622.73

    Type:
    Unknown

    AlogP:
    5.42

    Polar Surface Area:
    132.98

    HBA:
    10

    HBD:
    4

    #RO5 Violations:
    2

    #Rotatable Bonds:
    11

    Passes Ro3:
    N

    QED Weighted:
    0.16

    DETAILS
  2. ALA4475243

    Name:
    (S)-1-(3-(4-Amino-5-(7-methoxy-5-methylbenzo[b]thi
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    Mol. Formula:
    C23H23N5O2S

    M.W.:
    433.54

    Type:
    Unknown

    AlogP:
    4.17

    Polar Surface Area:
    86.27

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.49

    DETAILS
  3. ALA4475216

    Name:
    (R)-N-(5-cyano-4-((1-methoxypropan-2-yl)amino)pyri
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    Mol. Formula:
    C26H31N7O5

    M.W.:
    521.58

    Type:
    Unknown

    AlogP:
    3.32

    Polar Surface Area:
    149.78

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
  4. ALA4474645

    Name:
    1-(3-(5-(7-Methoxy-5-methylbenzo[b]thiophen-2-yl)-
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    Mol. Formula:
    C24H25N5O2S

    M.W.:
    447.56

    Type:
    Unknown

    AlogP:
    4.63

    Polar Surface Area:
    72.28

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  5. ALA4538678

    Name:
    N-(3-((4-(2-hydroxyethyl)piperazin-1-yl)methyl)-5-
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    Mol. Formula:
    C29H30F3N5O2

    M.W.:
    537.59

    Type:
    Unknown

    AlogP:
    4.92

    Polar Surface Area:
    84.49

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.31

    DETAILS
  6. ALA4525313

    Name:
    N-(3-(2-cyanopropan-2-yl)phenyl)-3-(1H-indazol-6-y
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    Mol. Formula:
    C25H22N4O

    M.W.:
    394.48

    Type:
    Unknown

    AlogP:
    5.59

    Polar Surface Area:
    81.57

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.47

    DETAILS
  7. ALA4521671

    Name:
    N-(3-((4-ethylpiperazin-1-yl)methyl)-5-(trifluorom
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    Mol. Formula:
    C29H30F3N5O

    M.W.:
    521.59

    Type:
    Unknown

    AlogP:
    5.95

    Polar Surface Area:
    64.26

    HBA:
    4

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.33

    DETAILS
  8. ALA4535664

    Name:
    N-(6-(2,6-Dichloro-3,5-dimethoxyphenyl)-1H-pyrazol
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    Mol. Formula:
    C21H16Cl2N4O3

    M.W.:
    443.29

    Type:
    Unknown

    AlogP:
    5.20

    Polar Surface Area:
    89.13

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  9. ALA4533697

    Name:
    (R)-N-(5-cyano-4-((1-methoxypropan-2-yl)oxy)pyridi
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    Mol. Formula:
    C25H28N6O6

    M.W.:
    508.54

    Type:
    Unknown

    AlogP:
    1.92

    Polar Surface Area:
    146.98

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  10. ALA4533292

    Name:
    N-(6-(2,6-Dichloro-3,5-dimethoxyphenyl)-1H-pyrazol
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    Mol. Formula:
    C25H25Cl2N7O3

    M.W.:
    542.43

    Type:
    Unknown

    AlogP:
    4.35

    Polar Surface Area:
    108.50

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  11. ALA4561437

    Name:
    N-(6-(2,6-Dichloro-3,5-dimethoxyphenyl)-1H-pyrazol
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    Mol. Formula:
    C24H24Cl2N6O3S

    M.W.:
    547.47

    Type:
    Unknown

    AlogP:
    5.01

    Polar Surface Area:
    95.61

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.35

    DETAILS
  12. ALA4561015

    Name:
    4-((2-Acrylamidophenyl)amino)-N-(3-chloro-5-methyl
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    Mol. Formula:
    C32H33ClN8O2

    M.W.:
    597.12

    Type:
    Unknown

    AlogP:
    6.05

    Polar Surface Area:
    114.52

    HBA:
    8

    HBD:
    4

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.17

    DETAILS
  13. ALA4559322

    Name:
    4-Methyl-3-(3-(1-(2-morpholinoethyl)-1H-pyrazol-4-
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    Mol. Formula:
    C31H29F3N6O2

    M.W.:
    574.61

    Type:
    Unknown

    AlogP:
    6.01

    Polar Surface Area:
    88.07

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.25

    DETAILS
  14. ALA4559175

    Name:
    N-(2-(4-Amino-5-(7-methoxy-5-methylbenzo[b]thiophe
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    Mol. Formula:
    C21H21N5O2S

    M.W.:
    407.50

    Type:
    Unknown

    AlogP:
    3.51

    Polar Surface Area:
    95.06

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.48

    DETAILS
  15. ALA4559114

    Name:
    N-(6-(2,6-Dichloro-3,5-dimethoxyphenyl)-1H-pyrazol
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    Mol. Formula:
    C26H28Cl2N6O3

    M.W.:
    543.46

    Type:
    Unknown

    AlogP:
    5.20

    Polar Surface Area:
    95.61

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.30

    DETAILS
  16. ALA4557987

    Name:
    1-(3-(4-Amino-5-(7-methoxy-5-methylbenzo[b]thiophe
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    Mol. Formula:
    C26H30N6O2S

    M.W.:
    490.63

    Type:
    Unknown

    AlogP:
    4.10

    Polar Surface Area:
    89.51

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  17. ALA4557949

    Name:
    4-(4-Cyclobutylpiperazin-1-yl)-N-(6-(2,6-dichloro-
    Show More

    Mol. Formula:
    C29H30Cl2N6O3

    M.W.:
    581.50

    Type:
    Unknown

    AlogP:
    5.88

    Polar Surface Area:
    95.61

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.28

    DETAILS
  18. ALA4557543

    Name:
    2-Chloro-N-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-1
    Show More

    Mol. Formula:
    C26H25Cl3N6O3

    M.W.:
    575.88

    Type:
    Unknown

    AlogP:
    5.61

    Polar Surface Area:
    95.61

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.31

    DETAILS
  19. ALA4556198

    Name:
    N-(5-cyano-4-(2-methoxyethoxy)pyridin-2-yl)-7-form
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    Mol. Formula:
    C24H26N6O6

    M.W.:
    494.51

    Type:
    Unknown

    AlogP:
    1.53

    Polar Surface Area:
    146.98

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  20. ALA4554916

    Name:
    1-(3-(4-Amino-5-(7-methoxy-5-methylbenzo[b]thiophe
    Show More

    Mol. Formula:
    C24H25N5O2S

    M.W.:
    447.56

    Type:
    Unknown

    AlogP:
    4.56

    Polar Surface Area:
    86.27

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS
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