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  1. ALA5287414

    Name:
    1-{N-[8-(9-imino-7-oxo-2,3,4,5,6,7,8,9,10,11-decah
    Show More

    Mol. Formula:
    C24H40N8O3

    M.W.:
    488.64

    Type:
    ---

    AlogP:
    2.69

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.16

    DETAILS
  2. ALA5286555

    Name:
    1-(2-hydroxyethyl)-1-{N-[8-(11-imino-9-oxo-2,3,4,5
    Show More

    Mol. Formula:
    C27H46N8O4

    M.W.:
    546.72

    Type:
    ---

    AlogP:
    2.83

    Polar Surface Area:
    174.69

    HBA:
    6

    HBD:
    8

    #RO5 Violations:
    2

    #Rotatable Bonds:
    11

    Passes Ro3:
    N

    QED Weighted:
    0.12

    DETAILS
  3. ALA5283905

    Name:
    1-[N-(8-{16-imino-22-methyl-14-oxo-2-oxa-13,15,17-
    Show More

    Mol. Formula:
    C31H46N8O3

    M.W.:
    578.76

    Type:
    ---

    AlogP:
    4.35

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
  4. ALA5283183

    Name:
    1-{N-[8-(4-imino-2-oxo-1,3,5-triazacyclotridecan-1
    Show More

    Mol. Formula:
    C21H42N8O2

    M.W.:
    438.62

    Type:
    ---

    AlogP:
    2.67

    Polar Surface Area:
    145.23

    HBA:
    4

    HBD:
    7

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.17

    DETAILS
  5. ALA5280623

    Name:
    1-[N-(8-{21-fluoro-16-imino-14-oxo-2-oxa-13,15,17-
    Show More

    Mol. Formula:
    C30H43FN8O3

    M.W.:
    582.73

    Type:
    ---

    AlogP:
    4.18

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
  6. ALA5280316

    Name:
    1-[N-(8-{16-imino-6-methyl-14-oxo-2-oxa-13,15,17-t
    Show More

    Mol. Formula:
    C31H46N8O3

    M.W.:
    578.76

    Type:
    ---

    AlogP:
    4.35

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
  7. ALA5279325

    Name:
    1-[N-(8-{16-imino-14-oxo-2-oxa-13,15,17-triazatric
    Show More

    Mol. Formula:
    C30H44N8O3

    M.W.:
    564.74

    Type:
    ---

    AlogP:
    4.04

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.14

    DETAILS
  8. ALA5279201

    Name:
    1-{N-[8-(11-imino-9-oxo-2,3,4,5,6,7,8,9,10,11,12,1
    Show More

    Mol. Formula:
    C26H44N8O2S

    M.W.:
    532.76

    Type:
    ---

    AlogP:
    3.63

    Polar Surface Area:
    137.39

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.11

    DETAILS
  9. ALA5290508

    Name:
    1-[N-(8-{22-fluoro-16-imino-14-oxo-2-oxa-13,15,17-
    Show More

    Mol. Formula:
    C30H43FN8O3

    M.W.:
    582.73

    Type:
    ---

    AlogP:
    4.18

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
  10. ALA5289877

    Name:
    1-[N-(8-{16-imino-21-methoxy-14-oxo-2-oxa-13,15,17
    Show More

    Mol. Formula:
    C31H46N8O4

    M.W.:
    594.76

    Type:
    ---

    AlogP:
    4.05

    Polar Surface Area:
    163.69

    HBA:
    6

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.12

    DETAILS
  11. ALA5288210

    Name:
    1-[N-(8-{7-fluoro-16-imino-14-oxo-2-oxa-13,15,17-t
    Show More

    Mol. Formula:
    C30H43FN8O3

    M.W.:
    582.73

    Type:
    ---

    AlogP:
    4.18

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
  12. ALA5276418

    Name:
    N-[8-(11-imino-9-oxo-2,3,4,5,6,7,8,9,10,11,12,13-d
    Show More

    Mol. Formula:
    C24H41N7O2

    M.W.:
    459.64

    Type:
    ---

    AlogP:
    3.50

    Polar Surface Area:
    139.35

    HBA:
    4

    HBD:
    6

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.19

    DETAILS
  13. ALA5272989

    Name:
    1-{N-[8-(11-imino-9-oxo-2,3,4,5,6,7,8,9,10,11,12,1
    Show More

    Mol. Formula:
    C27H46N8O3

    M.W.:
    530.72

    Type:
    ---

    AlogP:
    3.81

    Polar Surface Area:
    145.67

    HBA:
    5

    HBD:
    6

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.16

    DETAILS
  14. ALA5272737

    Name:
    1-{N-[8-(10-imino-8-oxo-3,4,5,6,7,8,9,10,11,12-dec
    Show More

    Mol. Formula:
    C25H42N8O3

    M.W.:
    502.66

    Type:
    ---

    AlogP:
    3.08

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.16

    DETAILS
  15. ALA5270387

    Name:
    1-{N-[6-(11-imino-9-oxo-2,3,4,5,6,7,8,9,10,11,12,1
    Show More

    Mol. Formula:
    C24H40N8O3

    M.W.:
    488.64

    Type:
    ---

    AlogP:
    2.69

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.18

    DETAILS
  16. ALA5270383

    Name:
    1-{N-[4-(11-imino-9-oxo-2,3,4,5,6,7,8,9,10,11,12,1
    Show More

    Mol. Formula:
    C22H36N8O3

    M.W.:
    460.58

    Type:
    ---

    AlogP:
    1.91

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.20

    DETAILS
  17. ALA5269695

    Name:
    1-(N-{8-[16-imino-14-oxo-6-(trifluoromethoxy)-2-ox
    Show More

    Mol. Formula:
    C31H43F3N8O4

    M.W.:
    648.73

    Type:
    ---

    AlogP:
    4.94

    Polar Surface Area:
    163.69

    HBA:
    6

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.11

    DETAILS
  18. ALA5268683

    Name:
    1-[N-(8-{7-chloro-16-imino-14-oxo-2-oxa-13,15,17-t
    Show More

    Mol. Formula:
    C30H43ClN8O3

    M.W.:
    599.18

    Type:
    ---

    AlogP:
    4.70

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
  19. ALA5268303

    Name:
    1-[N-(8-{22-chloro-16-imino-14-oxo-2-oxa-13,15,17-
    Show More

    Mol. Formula:
    C30H43ClN8O3

    M.W.:
    599.18

    Type:
    ---

    AlogP:
    4.70

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
  20. ALA5267257

    Name:
    1-[N-(8-{16-imino-21-methyl-14-oxo-2-oxa-13,15,17-
    Show More

    Mol. Formula:
    C31H46N8O3

    M.W.:
    578.76

    Type:
    ---

    AlogP:
    4.35

    Polar Surface Area:
    154.46

    HBA:
    5

    HBD:
    7

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.13

    DETAILS
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