Compounds

Type:
Unknown

AlogP:
5.08

Polar Surface Area:
95.32

HBA:
4

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4568035

Name:
(4-(4-(3-amino-1H-indazol-4-yl)benzoyl)piperazin-1
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Mol. Formula:
C26H25N5O2

M.W.:
439.52

Type:
Unknown

AlogP:
3.72

Polar Surface Area:
95.32

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.51

DETAILS

ALA4517204

Name:
4-(3-Amino-1H-indazol-6-yl)-N-(2-(4-fluorobenzamid
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Mol. Formula:
C23H20FN5O2

M.W.:
417.44

Type:
Unknown

AlogP:
3.11

Polar Surface Area:
112.90

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4549969

Name:
4-(3-Amino-1H-indazol-6-yl)-N-(2-(4-methylbenzamid
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Mol. Formula:
C24H23N5O2

M.W.:
413.48

Type:
Unknown

AlogP:
3.28

Polar Surface Area:
112.90

HBA:
4

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.36

DETAILS

ALA4547441

Name:
4-(3-Amino-1H-indazol-6-yl)-N-(2-(4-(dimethylamino
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Mol. Formula:
C25H26N6O2

M.W.:
442.52

Type:
Unknown

AlogP:
3.04

Polar Surface Area:
116.14

HBA:
5

HBD:
4

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.33

DETAILS

ALA4744950

Name:
4-fluoro-N-(3-(4-(imidazo[1,2-b]pyridazin-3-yl)-1H
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Mol. Formula:
C23H17FN6O

M.W.:
412.43

Type:
Unknown

AlogP:
4.28

Polar Surface Area:
77.11

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4743300

Name:
3-fluoro-N-(3-(4-(imidazo[1,2-b]pyridazin-3-yl)-1H
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Mol. Formula:
C23H17FN6O

M.W.:
412.43

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.28

Polar Surface Area:
77.11

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.48

DETAILS

ALA4743038

Name:
N-(4-methyl-3-(4-(pyrazolo[1,5-a]pyrimidin-6-yl)-1
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Mol. Formula:
C24H17F3N6O

M.W.:
462.44

Type:
Unknown

AlogP:
5.16

Polar Surface Area:
77.11

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4741331

Name:
4-methoxy-N-(4-methyl-3-(4-(pyrazolo[1,5-a]pyrimid
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Mol. Formula:
C24H20N6O2

M.W.:
424.46

Type:
Unknown

AlogP:
4.15

Polar Surface Area:
86.34

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4776133

Name:
N-[3-(3-Amino-1H-indazol-4-ylethynyl)-phenyl]-3-fl
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Mol. Formula:
C23H14F4N4O

M.W.:
438.38

Type:
Unknown

AlogP:
4.96

Polar Surface Area:
83.80

HBA:
3

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.31

DETAILS

ALA4762806

Name:
N-(3-(4-(imidazo[1,2-b]pyridazin-3-yl)-1H-pyrazol-
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Mol. Formula:
C24H17F3N6O

M.W.:
462.44

5 activity values

Type:
Unknown

AlogP:
5.16

Polar Surface Area:
77.11

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.40

DETAILS

ALA4760801

Name:
3-chloro-N-(3-(4-(imidazo[1,2-b]pyridazin-3-yl)-1H
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Mol. Formula:
C23H17ClN6O

M.W.:
428.88

Type:
Unknown

AlogP:
4.80

Polar Surface Area:
77.11

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.45

DETAILS

ALA4759869

Name:
N-(3-(4-(imidazo[1,2-b]pyridazin-3-yl)-1H-pyrazol-
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Mol. Formula:
C24H20N6O2

M.W.:
424.46

1 activity values

1 unique targets

Type:
Unknown

AlogP:
4.15

Polar Surface Area:
86.34

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.46

DETAILS

ALA4780910

Name:
N-[3-(3-Amino-1H-indazol-4-ylethynyl)-phenyl]-3-mo
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Mol. Formula:
C27H22F3N5O2

M.W.:
505.50

Type:
Unknown

AlogP:
4.65

Polar Surface Area:
96.27

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.35

DETAILS

ALA4780376

Name:
N-(3-(4-(imidazo[1,2-b]pyridazin-3-yl)-1H-pyrazol-
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Mol. Formula:
C28H27N7O2

M.W.:
493.57

Type:
Unknown

AlogP:
3.97

Polar Surface Area:
89.58

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4780226

Name:
3-(3-Amino-1H-indazol-4-ylethynyl)-N-[3-(4-methyl-
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Mol. Formula:
C29H27F3N6O

M.W.:
532.57

Type:
Unknown

AlogP:
4.56

Polar Surface Area:
90.28

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA4779313

Name:
N-(4-methyl-3-(4-(pyrazolo[1,5-a]pyrimidin-6-yl)-1
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Mol. Formula:
C28H27N7O2

M.W.:
493.57

1 activity values

1 unique targets

Type:
Unknown

AlogP:
3.97

Polar Surface Area:
89.58

HBA:
8

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4776468

Name:
3-(3-Amino-1H-indazol-4-ylethynyl)-N-(4-morpholin-
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Mol. Formula:
C28H24F3N5O2

M.W.:
519.53

Type:
Unknown

AlogP:
4.65

Polar Surface Area:
96.27

HBA:
5

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.34

DETAILS

ALA4591513

Name:
(4-(4-(3-amino-1H-indazol-6-yl)benzoyl)piperazin-1
Show More⌵

Mol. Formula:
C26H21ClF3N5O2

M.W.:
527.93

Type:
Unknown

AlogP:
5.08

Polar Surface Area:
95.32

HBA:
4

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.39

DETAILS

ALA4584148

Name:
4-(3-Amino-1H-indazol-4-yl)-N-(2-(4-fluorobenzamid
Show More⌵

Mol. Formula:
C23H20FN5O2

M.W.:
417.44