Type:
Small molecule

AlogP:
5.69

Polar Surface Area:
109.90

HBA:
5

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.24

Type:
Small molecule

AlogP:
2.96

Polar Surface Area:
126.69

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.37

Type:
Small molecule

AlogP:
6.45

Polar Surface Area:
75.63

HBA:
5

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.52

Type:
Small molecule

AlogP:
5.21

Polar Surface Area:
75.63

HBA:
5

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.72

Type:
Small molecule

AlogP:
4.82

Polar Surface Area:
75.63

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.77

Type:
Small molecule

AlogP:
6.37

Polar Surface Area:
100.13

HBA:
5

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.27

Type:
Small molecule

AlogP:
6.52

Polar Surface Area:
96.97

HBA:
5

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.27

Type:
Small molecule

AlogP:
5.30

Polar Surface Area:
79.90

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.65

Type:
Small molecule

AlogP:
4.17

Polar Surface Area:
79.90

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.76

Type:
Small molecule

AlogP:
4.70

Polar Surface Area:
75.99

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.81

Type:
Small molecule

AlogP:
5.37

Polar Surface Area:
79.90

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.67

Type:
Small molecule

AlogP:
6.28

Polar Surface Area:
79.90

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.47

Type:
Small molecule

AlogP:
6.58

Polar Surface Area:
68.90

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.44

Type:
Small molecule

AlogP:
4.75

Polar Surface Area:
79.90

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.73

Type:
Small molecule

AlogP:
5.50

Polar Surface Area:
80.42

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.43

Type:
Small molecule

AlogP:
7.22

Polar Surface Area:
62.32

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.31

Type:
Small molecule

AlogP:
4.39

Polar Surface Area:
80.42

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.53

Type:
Small molecule

AlogP:
4.08

Polar Surface Area:
80.42

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.55

Type:
Small molecule

AlogP:
5.55

Polar Surface Area:
80.42

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.42

Type:
Small molecule

AlogP:
7.14

Polar Surface Area:
62.32

HBA:
2

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.39