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  1. ALA4877719

    Name:
    2-((1-(2,4-difluorobenzyl)-4-fluoropiperidin-4-yl)
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    Mol. Formula:
    C24H26F3NO3

    M.W.:
    433.47

    Type:
    Unknown

    AlogP:
    4.73

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.66

    DETAILS
  2. ALA4877366

    Name:
    5-fluoro-2-((4-fluoro-1-(3-fluorobenzyl)piperidin-
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    Mol. Formula:
    C23H24F3NO2

    M.W.:
    403.44

    Type:
    Unknown

    AlogP:
    4.72

    Polar Surface Area:
    29.54

    HBA:
    3

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.72

    DETAILS
  3. ALA4877089

    Name:
    2-((1-(3,5-difluorobenzyl)-4-fluoropiperidin-4-yl)
    Show More

    Mol. Formula:
    C24H26F3NO3

    M.W.:
    433.47

    Type:
    Unknown

    AlogP:
    4.73

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.66

    DETAILS
  4. ALA4876130

    Name:
    5,6-dibutoxy-2-((4-fluoro-1-(2-fluorobenzyl)piperi
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    Mol. Formula:
    C30H39F2NO3

    M.W.:
    499.64

    Type:
    Unknown

    AlogP:
    6.93

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    12

    Passes Ro3:
    N

    QED Weighted:
    0.30

    DETAILS
  5. ALA4873794

    Name:
    5-fluoro-2-((4-fluoro-1-(2-fluorobenzyl)piperidin-
    Show More

    Mol. Formula:
    C23H24F3NO2

    M.W.:
    403.44

    Type:
    Unknown

    AlogP:
    4.72

    Polar Surface Area:
    29.54

    HBA:
    3

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.72

    DETAILS
  6. ALA4871843

    Name:
    2-((4-fluoro-1-(3-(trifluoromethyl)benzyl)piperidi
    Show More

    Mol. Formula:
    C25H27F4NO3

    M.W.:
    465.49

    Type:
    Unknown

    AlogP:
    5.47

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  7. ALA4871360

    Name:
    5-fluoro-2-((4-fluoro-1-(4-fluorobenzyl)piperidin-
    Show More

    Mol. Formula:
    C23H24F3NO2

    M.W.:
    403.44

    Type:
    Unknown

    AlogP:
    4.72

    Polar Surface Area:
    29.54

    HBA:
    3

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.72

    DETAILS
  8. ALA4869273

    Name:
    2-((4-fluoro-1-(3-fluorobenzyl)piperidin-4-yl)meth
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    Mol. Formula:
    C28H35F2NO3

    M.W.:
    471.59

    Type:
    Unknown

    AlogP:
    6.15

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
  9. ALA4869023

    Name:
    2-((4-fluoro-1-(2-(trifluoromethyl)benzyl)piperidi
    Show More

    Mol. Formula:
    C25H27F4NO3

    M.W.:
    465.49

    Type:
    Unknown

    AlogP:
    5.47

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  10. ALA4868720

    Name:
    3-((4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2
    Show More

    Mol. Formula:
    C25H27FN2O3

    M.W.:
    422.50

    Type:
    Unknown

    AlogP:
    4.32

    Polar Surface Area:
    62.56

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.69

    DETAILS
  11. ALA4867751

    Name:
    6-fluoro-2-((4-fluoro-1-(4-fluorobenzyl)piperidin-
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    Mol. Formula:
    C23H24F3NO2

    M.W.:
    403.44

    Type:
    Unknown

    AlogP:
    4.72

    Polar Surface Area:
    29.54

    HBA:
    3

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.72

    DETAILS
  12. ALA4867651

    Name:
    2-((4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2
    Show More

    Mol. Formula:
    C25H27FN2O3

    M.W.:
    422.50

    Type:
    Unknown

    AlogP:
    4.32

    Polar Surface Area:
    62.56

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.69

    DETAILS
  13. ALA4867225

    Name:
    6-(cyclopropylmethoxy)-2-((1-(2,4-difluorobenzyl)-
    Show More

    Mol. Formula:
    C27H30F3NO3

    M.W.:
    473.54

    Type:
    Unknown

    AlogP:
    5.51

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.51

    DETAILS
  14. ALA4866280

    Name:
    2-((4-fluoro-1-(2-fluorophenethyl)piperidin-4-yl)m
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    Mol. Formula:
    C25H29F2NO3

    M.W.:
    429.51

    Type:
    Unknown

    AlogP:
    4.63

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.64

    DETAILS
  15. ALA4865844

    Name:
    2-((4-fluoro-1-(4-(trifluoromethoxy)benzyl)piperid
    Show More

    Mol. Formula:
    C25H27F4NO4

    M.W.:
    481.49

    Type:
    Unknown

    AlogP:
    5.35

    Polar Surface Area:
    48.00

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
  16. ALA4864886

    Name:
    2-((4-fluoro-1-(3-fluorobenzyl)piperidin-4-yl)meth
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    Mol. Formula:
    C23H25F2NO2

    M.W.:
    385.45

    Type:
    Unknown

    AlogP:
    4.58

    Polar Surface Area:
    29.54

    HBA:
    3

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.75

    DETAILS
  17. ALA4864695

    Name:
    6-(cyclopropylmethoxy)-2-((4-fluoro-1-(3-fluoroben
    Show More

    Mol. Formula:
    C27H31F2NO3

    M.W.:
    455.55

    Type:
    Unknown

    AlogP:
    5.37

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.54

    DETAILS
  18. ALA4864526

    Name:
    6-(cyclopropylmethoxy)-2-((4-fluoro-1-(2-fluoroben
    Show More

    Mol. Formula:
    C27H31F2NO3

    M.W.:
    455.55

    Type:
    Unknown

    AlogP:
    5.37

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.54

    DETAILS
  19. ALA4863729

    Name:
    2-((4-fluoro-1-(4-fluorobenzyl)piperidin-4-yl)meth
    Show More

    Mol. Formula:
    C23H25F2NO2

    M.W.:
    385.45

    Type:
    Unknown

    AlogP:
    4.58

    Polar Surface Area:
    29.54

    HBA:
    3

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.75

    DETAILS
  20. ALA4863392

    Name:
    2-((4-fluoro-1-(3-methylbenzyl)piperidin-4-yl)meth
    Show More

    Mol. Formula:
    C25H30FNO3

    M.W.:
    411.52

    Type:
    Unknown

    AlogP:
    4.76

    Polar Surface Area:
    38.77

    HBA:
    4

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.69

    DETAILS
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