Compounds

Type:
Unknown

AlogP:
3.74

Polar Surface Area:
84.31

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.52

DETAILS

ALA4781616

Name:
N-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1-(1,1,1-triflu
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Mol. Formula:
C18H14F3N5

M.W.:
357.34

2 unique targets

Type:
Unknown

AlogP:
4.92

Polar Surface Area:
66.49

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.55

DETAILS

ALA4551081

Name:
3-isopropyl-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)benz
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Mol. Formula:
C16H15N5O

M.W.:
293.33

Type:
Unknown

AlogP:
3.97

Polar Surface Area:
79.63

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA4756046

Name:
1-ethyl-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquino
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Mol. Formula:
C17H15N5

M.W.:
289.34

2 unique targets

Type:
Unknown

AlogP:
3.81

Polar Surface Area:
66.49

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA4755785

Name:
6-(1H-pyrazolo[4,3-b]pyridin-3-ylamino)-2-(cyclobu
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Mol. Formula:
C20H19N5O

M.W.:
345.41

Type:
Unknown

AlogP:
3.82

Polar Surface Area:
75.60

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4764520

Name:
6-(1H-pyrazolo[4,3-b]pyridin-3-ylamino)-2-methylis
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Mol. Formula:
C16H13N5O

M.W.:
291.31

Type:
Unknown

AlogP:
2.55

Polar Surface Area:
75.60

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4754632

Name:
N1,N1-diethyl-N6-(1H-pyrazolo[4,3-b]pyridin-3-yl)i
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Mol. Formula:
C19H20N6

M.W.:
332.41

Type:
Unknown

AlogP:
4.10

Polar Surface Area:
69.73

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4754007

Name:
1-(3,3-difluoropyrrolidin-1-yl)-N-(1H-pyrazolo[4,3
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Mol. Formula:
C19H16F2N6

M.W.:
366.38

Type:
Unknown

AlogP:
4.10

Polar Surface Area:
69.73

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA4753444

Name:
N-(1H-pyrazolo[4,3-b]pyridin-3-yl)quinazolin-6-ami
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Mol. Formula:
C14H10N6

M.W.:
262.28

1 activity values

Type:
Unknown

AlogP:
2.64

Polar Surface Area:
79.38

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4753304

Name:
1-cyclopropyl-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)is
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Mol. Formula:
C18H15N5

M.W.:
301.35

2 unique targets

Type:
Unknown

AlogP:
4.13

Polar Surface Area:
66.49

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA4751992

Name:
N-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1-(pyrrolidin-1
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Mol. Formula:
C19H18N6

M.W.:
330.40

Type:
Unknown

AlogP:
3.85

Polar Surface Area:
69.73

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.60

DETAILS

ALA4751941

Name:
1-(4-methylpiperazin-1-yl)-N-(1H-pyrazolo[4,3-b]py
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Mol. Formula:
C20H21N7

M.W.:
359.44

Type:
Unknown

AlogP:
3.00

Polar Surface Area:
72.97

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4750744

Name:
6-(1H-pyrazolo[4,3-b]pyridin-3-ylamino)-2-cyclopen
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Mol. Formula:
C20H19N5O

M.W.:
345.41

Type:
Unknown

AlogP:
4.13

Polar Surface Area:
75.60

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.59

DETAILS

ALA4795205

Name:
N-(1H-pyrazolo[4,3-b]pyridin-3-yl)quinoxalin-6-ami
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Mol. Formula:
C14H10N6

M.W.:
262.28

1 activity values

Type:
Unknown

AlogP:
2.64

Polar Surface Area:
79.38

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4794816

Name:
1-(piperidin-1-yl)-N-(1H-pyrazolo[4,3-b]pyridin-3-
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Mol. Formula:
C20H20N6

M.W.:
344.42

Type:
Unknown

AlogP:
4.24

Polar Surface Area:
69.73

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4556685

Name:
3-Neopentyl-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isot
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Mol. Formula:
C17H18N6S

M.W.:
338.44

10 activity values

4 unique targets

Type:
Unknown

AlogP:
4.29

Polar Surface Area:
79.38

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
3

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4800673

Name:
N-(1H-pyrazolo[4,3-b]pyridin-3-yl)quinolin-7-amine

Mol. Formula:
C15H11N5

M.W.:
261.29

1 activity values

Type:
Unknown

AlogP:
3.25

Polar Surface Area:
66.49

HBA:
4

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA4797966

Name:
N1-(2-methoxyethyl)-N6-(1H-pyrazolo[4,3-b]pyridin-
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Mol. Formula:
C18H18N6O

M.W.:
334.38