Type:
Small molecule

AlogP:
6.20

Polar Surface Area:
103.70

HBA:
3

HBD:
3

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.27

Type:
Small molecule

AlogP:
3.18

Polar Surface Area:
134.63

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.41

Type:
Small molecule

AlogP:
3.18

Polar Surface Area:
134.63

HBA:
7

HBD:
3

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.41

Type:
Small molecule

AlogP:
6.01

Polar Surface Area:
111.33

HBA:
7

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.37

Type:
Small molecule

AlogP:
4.78

Polar Surface Area:
96.38

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.50

Type:
Small molecule

AlogP:
4.78

Polar Surface Area:
96.38

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.50

Type:
Small molecule

AlogP:
4.78

Polar Surface Area:
96.38

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.50

Type:
Small molecule

AlogP:
4.78

Polar Surface Area:
87.15

HBA:
4

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.56

Type:
Small molecule

AlogP:
5.46

Polar Surface Area:
49.85

HBA:
3

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.55

Type:
Small molecule

AlogP:
5.42

Polar Surface Area:
77.92

HBA:
3

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.54

Type:
Small molecule

AlogP:
5.81

Polar Surface Area:
77.92

HBA:
3

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.48

Type:
Small molecule

AlogP:
5.86

Polar Surface Area:
86.71

HBA:
3

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.35

Type:
Small molecule

AlogP:
4.55

Polar Surface Area:
76.07

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.68

Type:
Small molecule

AlogP:
4.54

Polar Surface Area:
66.84

HBA:
3

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.75

Type:
Small molecule

AlogP:
5.29

Polar Surface Area:
57.61

HBA:
2

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.65

Type:
Small molecule

AlogP:
4.53

Polar Surface Area:
57.61

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.82

Type:
Small molecule

AlogP:
5.38

Polar Surface Area:
57.61

HBA:
2

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.56

Type:
Small molecule

AlogP:
4.30

Polar Surface Area:
77.84

HBA:
3

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.73

Type:
Small molecule

AlogP:
5.10

Polar Surface Area:
57.61

HBA:
2

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.69

Type:
Small molecule

AlogP:
4.53

Polar Surface Area:
57.61

HBA:
2

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.82